先端医療シリーズ22　整形外科の最新医療

出版社： 先端医療技術研究所
著者：
発行日： 2003-07-17
分野： 臨床医学：外科  >  整形外科学
ISBN： 4925089285
電子書籍版： 2003-07-17 （初版第1刷）
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2000年10月30日に先端医療ｼﾘｰｽﾞ8「整形外科-診断と治療の最先端」が刊行され、そこでは20世紀末の進歩の最先端が総括されていた。約3年を経て、本佳が出版されることになったが、まさに21世紀初頭における新しい遺伝子レベルの医療、分子レベルの解析などが一段と進み、整形外科学の最前線の重要課題が網羅されている。

目次

  • 先端医療シリーズ22　整形外科の最新

    ―目次―

    序　章
    　1. 「運動器の１０年」の臨床の課題と展望
    　2. 「運動器の１０年」の研究課題と展望
    第１章　遺伝子診断
    　1. 課題と展望
    　2. 骨系統疾患と遺伝子異常
    　3. 遺伝子診断によるステロイド性大腿骨頭壊死症の発生予測
    　4. 関節リウマチの遺伝子診断
    第２章　骨代謝と新しい治療
    　1. 課題と展望
    　2. 骨形成と骨吸収の分子ﾒｶﾆｽﾞﾑ/TGF-β/BMPｼｸﾞﾅﾙを中心に
    　3. 骨延長の分子メカニズム
    　4. 骨組織再生の促進
    　5. 生体電気刺激と超音波による骨折治癒
    第３章　骨粗鬆症
    　1. 課題と展望
    　2. 骨粗鬆症の分子病態
    　3. 骨粗鬆症の遺伝的背景
    　4．骨粗鬆症に対する薬物治療
    第４章　軟骨の変性と変形性関節症
    　1. 課題と展望
    　2. 変形性関節症における軟骨破壊とNO
    　3. Aggrecanaseによる軟骨変性
    　4. ヒアルロン酸の効果
    　5. 軟骨細胞に対する遺伝子治療
    第５章　軟骨損傷・再生と新しい治療
    　1. 課題と展望
    　2. 組織工学的手法を用いた軟骨修復
    　3. 培養骨髄間葉系細胞の応用への展望
    　4. 細胞培養の足場（Scaffold）と細胞増殖因子のDDS技術による
    　　　 組織再生誘導
    第６章　関節リウマチ
    　1. 転写とリウマチ
    　2. 病態と治療
    　3. 生物製剤による治療
    　4. RAのMRIによる診断
    第７章　脊髄損傷再生
    　1. 脊髄再生研究の現状と可能性
    　2. 脊髄損傷後のアポトーシスとその抑制
    　3. 樹状細胞を用いた脊髄再生
    　4. 内在性神経前駆細胞と損傷脊髄の再生誘導
    　5. 脊髄損傷にたいする神経幹細胞移植
    　6. グリア性再生阻害因子と脊髄再生
    　7. MEK遺伝子導入による脊髄機能回復
    第８章　末梢神経再生
    　1. 課題と展望
    　2. 末梢神経切断端の再生軸索誘導能
    　3. 末梢神経同種移植
    　4. 新規生体吸収材料チューブを用いた人工神経の開発
    　5. Tissue Engineering手法を用いたﾊｲﾌﾞﾘｯﾄﾞ型人工神経
    　6. 培養シュワン細胞を組み込んだﾊｲﾌﾞﾘｯﾄﾞ型人工神経
    第９章　新しい脊髄機能解析法
    　1. Neuroimagingによる脳・脊髄上行路の機能解析
    　2. 光計測法を用いた脊髄内神経興奮伝播障害の解析
    　3. 脊髄誘発磁界による脊髄内神経活動局在の解析
    　4. PETによる新しい脊髄画像診断、機能解析
    第１０章 膝靭帯損傷に対する治療医学の進歩
    　1. 課題と展望
    　2. 膝靭帯損傷のバイオメカニクスの進歩
    　3. 十字靭帯再建術式の進歩
    　4. 靭帯再建術と生体組織工学
    　5. 靭帯再建術と遺伝子治療
    第１１章　新しい膝関節形成術の進歩
    　1. 課題と展望
    　2. 下肢ｱﾗｲﾒﾝﾄ３次元評価ｼｽﾃﾑと人工関節手術への臨床応用
    　3. 人工膝関節全置換術における新機構（Mobile Knee）
    　4. 人工膝関節全置換術における新素材（セラミック）
    　5. 人工膝関節全置換術における新関節形状（Bisurface Knee）
    第１２章　骨・軟部腫瘍の診断と治療
    　1. 悪性骨・軟部腫瘍の診断と治療における課題と展望
    　2. MDCTとMRIによる診断の進歩
    　3. 免疫組織化学染色と遺伝子診断
    　4. 骨肉腫におけるゲノム解析
    　　　-Comparative Genomic-Hybridizationによる解析-
    　5. 遺伝子治療
    　6. 分子標的治療
    第１３章　ロボット手術
    　1. コンピューター支援手術
    　2. 脊椎外科とコンピュータナビゲーションシステム
    　3. コンピュータナビゲーションシステム（股関節）
    　4. ロボット手術（股関節）
    　5. ロボット手術（膝関節）
    第１４章　各種製品の臨床評価
    　1. 腰部脊椎管狭窄に対するリマプロストアルファデスク
    　　（プロレナール）の治療効果の検討
    　2. 変形性膝関節症に対するアルツディスポの効果
    　3. 膝間接手術後の肺塞栓予防を目的としたﾌｯﾄﾎﾟﾝﾌﾟの使用と
    　　その有用性

    技術資料編

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参考文献のリンクは、リンク先の都合等により正しく表示されない場合がありますので、あらかじめご了承下さい。

本参考文献は電子書籍掲載内容を元にしております。

序章

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第1章 遺伝子診断

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第2章 骨代謝と新しい治療

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第3章 骨粗鬆症

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第4章 軟骨の変性と変形性関節症

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第5章 軟骨損傷・再生と新しい治療

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第6章 関節リウマチ

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第7章 脊髄損傷再生

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第8章 末梢神経再生

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第9章 新しい脊髄機能解析法

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第10章 膝靱帯損傷に対する治療医学の進歩

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24) 安田和則, 酒井俊彦:後十字靱帯再建術. 多重束膝屈筋腱-hybrid代用材料を用いた鏡視下再建術. 整形外科 50:962-967, 1999
 
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第11章 新しい膝関節形成術の進歩

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第12章 骨・軟部腫瘍の診断と治療

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第13章 ロボット手術

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5) Koyama T, Sugano N, Sasama T et al:A novel laser guidance system to present the information of navigation direction in the surgical field. Trans Orthop Res Soc 28:1090, 2003
 
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6) Pitto RP, Koessler M and Draenert K:The John Chamley Award. Prophylaxis of fat and bone marrow embolism in cemented total hip arthroplasty. Clin Orthop:23-34, 1998
 
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8) Digioia AM 3rd, Jaramaz B, PlakSeychuk AY et al:Comparison of a mechanical acetabular alignment guide with computer placement of the socket. J Arthroplasty 17:359-364, 2002
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4) Bargar WL, Bauer A and Bomer M:Primary and revision total hip replacement using the Robodoc system. Clin Orthop:82-91, 1998
 
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6) Delp SL, Stulberg SD, Davies B et al:Computer assisted knee replacement. Clin Orthop:49-56, 1998
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7) Ybshino N, Takai S, Ohtsuki Y et al:Computed tomography measurement of the surgical and clinical trartsepicondylar axis of the distal femur in osteoarthritic knees. J Arthroplasty 16:493-497, 2001
 
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11) Griffin FM, Insall JN and Scuderi GR:Accuracy of soft tissue balancing in total knee arthroplasty. J Arthroplasty 15:970-973, 2000
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第14章 各種製品の臨床評価

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