急性腎不全・AKIを理解する

出版社： 東京医学社
著者：
発行日： 2010-06-30
分野： 臨床医学：内科  >  腎臓
ISBN： 9784885631962
電子書籍版： 2010-06-30 （第1版）
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急性腎不全はどのような疾患概念として変化してきたか、急性腎不全の予後を改善するためにどのような研究が行われてきたか、現在問題は何か。急性腎不全の臨床と基礎的研究の歴史を振り返り、それらの最前線についてまとめる。

目次

  • 急性腎不全・AKIを理解する

    ―目次―

    第1章?　急性腎不全とはなにか？?─急性腎不全とAKI─?
    1　急性腎不全の概念の変遷（急性腎不全からAKIへ）? ?
    2　急性腎不全の診断? ?
    3　Acute kidney injury（AKI）の診断? ??
    4　急性腎不全かAKIか？?
    将来展望?

    第2章?　急性腎不全はどのような状況で発生するか？
    　　　　　─急性腎不全の原因と疫学─?
    1　急性腎不全の原因の変遷? ?
    2　急性腎不全の原因?
    3　急性腎不全の発症頻度?
    将来展望?

    第3章　?急性腎不全の腎組織変化? ?
    1　近位尿細管の壊死? ?
    2　近位尿細管のみの障害か?
    3　糸球体の変化
    4　尿細管周囲毛細血管と間質の変化?
    5　壊死かアポトーシスか
    6　尿細管細胞の極性の喪失と脱落?
    将来展望?

    第4章　?急性腎不全でなぜ高窒素血症が生じるか？
    　　　　　─急性腎不全の発症機序─?
    1　狭義の急性腎不全で腎機能が低下するメカニズム? ?
    2　尿細管細胞の極性の喪失と腎機能低下?
    将来展望?

    第5章?　急性腎不全の発症に介在する因子?
    1　血管作動性物質?
    2　活性酸素?
    3　一酸化窒素（nitoxic oxide：NO）?
    4　炎　症? ?
    将来展望?

    第6章?　急性腎不全の腎臓で防御的に働く因子? ?
    1　熱ショック蛋白（HSP）
    2　成長因子? ?
    3　低酸素誘導因子（HIF?1α）?
    4　細胞周期調節因子?
    5　臨床応用へ?
    将来展望?

    第7章?　急性腎不全からの回復?
    1　再生細胞の起源?
    2　尿細管の再生を促す（関与する）因子?
    将来展望? ?

    第8章?　多臓器不全としての急性腎不全・AKI? ?
    1　多臓器不全と感染症の合併が予後を悪くする?
    2　SIRS，感染症による急性腎不全・多臓器不全の発症機序?
    3　臓器相関 ─1臓器の不全が他の臓器不全の発症に関与─? ?
    4　多臓器不全に伴う急性腎不全の予後改善の試み?
    5　急性腎不全発症の早期診断・診断マーカー?
    将来展望?

    第9章?　急性腎不全の予後? ?
    1　生命予後?
    2　生命予後の予測因子? ?
    3　急性腎不全の発症は各種疾患の生命予後に影響する?
    4　腎機能の回復?
    将来展望? ?

    附　章?　動物の急性腎不全モデル?
    1　虚血性急性腎不全モデル?
    2　腎毒性急性腎不全モデル? ?
    3　グリセロール誘発急性腎不全モデル?
    4　敗血症関連急性腎不全モデル?
    5　特殊な急性腎不全モデル?

この書籍の参考文献

参考文献のリンクは、リンク先の都合等により正しく表示されない場合がありますので、あらかじめご了承下さい。

本参考文献は電子書籍掲載内容を元にしております。

第1章 急性腎不全とはなにか ? - 急性腎不全とAKI -

P.11 掲載の参考文献
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第2章 急性腎不全はどのような状況で発生するか ? - 急性腎不全の原因と疫学 -

P.24 掲載の参考文献
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第3章 急性腎不全の腎組織変化

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第4章 急性腎不全でなぜ高窒素血症が生じるか ? - 急性腎不全の発症機序 -

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第5章 急性腎不全の発症に介在する因子

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第6章 急性腎不全の腎臓で防御的に働く因子

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第7章 急性腎不全からの回復

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第8章 多臓器不全としての急性腎不全・AKI

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第9章 急性腎不全の予後

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附章 動物の急性腎不全モデル

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