先進医療NAVIGATOR　今日の再生医療

出版社： 日本医学出版
著者：
発行日： 2016-06-30
分野： 臨床医学：一般  >  臨床医学一般
ISBN： 9784865770186
電子書籍版： 2016-06-30 （初版第1刷）
書籍・雑誌
≪全国送料無料でお届け≫
取寄せ目安：8～14営業日

4,400 円(税込)

購入する
電子書籍
章別単位での購入はできません
ブラウザ、アプリ閲覧

4,400 円(税込)

購入する

商品紹介

iPS細胞研究、ティッシュ・エンジニアリングの最前線をはじめ、Muse細胞と再生治療、脳梗塞に他家の細胞を用いた臨床研究など、再生医療研究の現在の状況を専門家が紹介。先進医療を実施している医療機関一覧も収録。

目次

  • 先進医療NAVIGATOR　今日の再生医療

    ―目次―

    第1章　再生医療の研究最前線
    　1．再生医療の研究最前線　
    　2．2iPS細胞研究最前線
    　3．3ティッシュ・エンジニアリング研究最前線

    第2章　診療科各科と再生医療の最前線
    　1．軟骨細胞とiPS細胞
    　2．幹細胞と再生医療
    　3．Muse細胞と再生治療
    　4．神経と再生療法
    　5．細胞シート製品による食道再生治療
    　6．消化器疾患と再生医療
    　7．呼吸器疾患と再生医療
    　8．糖尿病と再生医療
    　9．耳鼻科と再生医療
    　10．ヒトiPS細胞を用いた脊髄損傷に対する再生医療
    　11．眼科と再生医療
    　12．皮膚の再生医療
    　13．腎臓内科・泌尿器科と再生医療
    　14．歯周領域における再生医療
    　15．網膜再生医療研究開発プロジェクトのTOPICS

    先進医療の各技術の概要
    　1．先進医療の概要
    　2．先進医療の各技術の概要
    　3．先進医療を実施している医療機関一覧

おすすめ商品

この書籍の参考文献

参考文献のリンクは、リンク先の都合等により正しく表示されない場合がありますので、あらかじめご了承下さい。

本参考文献は電子書籍掲載内容を元にしております。

第1章 再生医療の研究最前線

P.3 掲載の参考文献
1) Pan G, Thomson JA. Nanog and transcriptional networks in embryonic stem cell pluripotency. Cell Res. 2007 : 17 : 42-49
PubMed
2) Yamanaka S. Induction of pluripotent stem cells from mouse fibroblasts by four transcription factors. Cell Prolif. 2008 : 41 : 51-56
PubMed
3) Miyagawa S, Fukushima S, Imanishi Y, Kawamura T, Mochizuki-Oda N, Masuda S, et al : Building a new treatment for heart failure-Transplantation of Induced Pluripotent Stem Cell-derived Cells into the Heart. Cur Gene Ther. 2016 Jan 18
 
4) Sawa Y, Yoshikawa Y, Toda K, Fukushima S, Yamazaki K, Ono M, et al : Safety and efficacy of autologous skeletal myoblast sheets (TCD-51073) for the treatment of severe chronic heart failure due to ischemic heart disease. Circ J. 2015 : 79 : 991-999
PubMed
5) Fukushima S, Sawa Y, Suzuki K. Choice of cell-delivery route for successful cell transplantation therapy for the heart. Future Cardiol. 2013 : 9 : 215-227
PubMed
6) Shudo Y, Miyagawa S, Fukushima S, Saito A, Shimizu T, Okano T, et al : Novel regenerative therapy using cell-sheet covered with omentum fiap delivers a huge number of cells in a porcine myocardial infarction model. J Thorac Cardiovasc Surg. 2011 : 42 : 1188-1196
 
7) Fukushima S, Miyagawa S, Sakai Y, Sawa Y. A sustained-release drug-delivery system of synthetic prostacyclin agonist, ONO-1301SR : a new reagent to enhance cardiac tissue salvage and/or regeneration in the damaged heart. Heart Fail Rev. 2015 ; 20 : 401-413
PubMed
P.7 掲載の参考文献
1) Takahashi K, Tanabe K, Ohnuki M, et al : Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007 ; 131 : 861-872
PubMed
2) Okita K, Nakagawa M, Hyenjong H, et al : Generation of mouse induced pluripotent stem cells without viral vectors. Science 2008 ; 322 : 949-953
PubMed
3) Warren L, Manos PD, Ahfeldt T, et al : Highly efficient reprogrammingtopluripotency anddirected differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 2010 ; 7 : 618-630
PubMed
4) Kim D, Kim CH, Moon JI, et al : Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 2009 ; 4 : 472-476
PubMed
5) Hou P, Li Y, Zhang X, et al : Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. Science 2013 ; 341 : 651-654
 
6) Nakagawa M, Taniguchi Y, Senda S, et al : A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells. Sci Rep 2014 ; 4 : 3594
PubMed
7) Hallett PJ, Cooper O, Sadi D, et al : Long-term health of dopaminergic neuron transplants in Parkinson's disease patients. Cell Rep 2014 ; 7 : 1755-1761
PubMed
8) Doi D, Morizane A, Kikuchi T, et al : maturation culture favors a reduction in the tumorigenicity and the dopaminergic function of human ESC-derived neural cells in a primate model of Parkinson's disease. Stem Cells 2012 ; 30 : 935-945
 
9) Doi D, Samata B, Katsukawa M, et al : Isolation of Human Induced Pluripotent Stem Cell-derived Dopaminergic Progenitors by Cell Sorting for Successful Transplantation. Stem Cell Reports 2014 ; 2 : 337-350
PubMed
P.10 掲載の参考文献
1) Kleinman H K, Martin G R : Matrigel : Basement membrane matrix with biological activity. Semin Cancer Biol 2005 ; 15 : 378-386
PubMed
2) Miyazaki T, Futaki S, Suemori H, et al : Laminin E8 fragments support efficient adhesion and expansion of dissociated human pluripotent stem cells. Nat Commun 2012 ; 3 : 1236
PubMed
3) 京都大学iPS細胞研究所 : 再生医療用iPS細胞について. http://ips.kuhp.kyoto-u.ac.jp/kuh/ips.html
 
4) VIACYTE Regenerating Health : ViaCyte Acquires Rights to BetaLogics Assets, Expanding and Extending Industry-Leading Prortfolio for Stem Cell-Derived Approaches to Type l Diabetes. http://viacyte.com/press-releases/viacyte-acquires-betalogics/
 
5) Szot GL, Yadav M, Lang J, et al : Tolerance induction and reversal of diabetes in mice transplanted with human embryonic stem cell-derived pancreatic endoderm. Cell Stem Cell 2015 ; 16 (2) : 148-157. doi : 10. 1016/j. stem2014. 12001.
 
6) Ohgawara H : Strategies for immunoisolation in islet transplantation : challenges for the twenty-first century. J Hepatobiliary Pancreat Surg 2000 ; 7 (4) : 374-379
 
7) Luan NM, Iwata H : Long-term allogeneic islet graft survival in prevascularized subcutaneous sites without immunosuppresslve treatment. Am J Transplant 2014 ; 14 (7) : 1533-1542
PubMed
8) Langer R, Vacanti Jp : Tissue engineering. Science 1993 ; 260 (5110) : 920-926
PubMed
9) Badylak SF, Weiss DJ, Caplan A, Macchiarini P : Engineered whole organs and complex tissues. Lancet 2012 ; 379 (9819) : 943-952. doi : 10. 1016/SO140-6736 (12) 60073-7.
 
10) Mahara A, Somekawa S, Kobayashi N, et al : Tissue-engineered acellular small diameter long-bypass grafts with neointima-inducing activity. Biomaterial 2015 ; 58 : 54-62
 
11) Takebe T, Enomura M, Yoshizawa E, et al : Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation. Cell Stem Cell 2015 ; 16 (5) : 556-565
PubMed

第2章 診療科各科と再生医療の最前線

P.16 掲載の参考文献
1) 再生医学. 日本医事新報, 4689 : 24-29, 2014
Medical*Online
2) Schwartz SD, et al : Human embryonic stem cell-derived retinal pigment epitheliurn in patients with age-related macular degeneration and Stargardt's macular dystrophy : follow-up of two open-label phase 1/2 studies. Lancet. 385 : 509-516. 2014
PubMed
3) 早川堯夫, 梅澤明弘山中伸弥, 小澤敬也, 大和雅之, 澤芳樹, 山口照英, 松山晃文, 佐藤陽治, 中内啓光. ヒトES細胞加工医薬品等の品質及び安全性の確保に関する指針案 (中間報告). 再生医療 9 (1) : 166-180. 2010
 
4) 独立行政法人医薬品医療機器総合機構 『iPS細胞等をもとに製造される細胞組織加工製品の造腫瘍性に関する議論のまとめ』http://www.pmda.go.jp/guide/kagakuiinkai/kagakuiinkai/h250820gijishidai/file/torimatomel.pdf
 
5) Takebe T, et al : Vascularized and functional human liver from an iPSC-derived organ bud transplant, Nature. 499 : 481-4. 2013
PubMed
6) Takebe T, et al : Generation of a vascularized and functional human liver from an iPSC-derived organ bud transplant. Nat Protoc. 9 : 396-409. 2014
PubMed
P.20 掲載の参考文献
1) Dezawa M, Takahashi I, Esaki M, et al : Sciatic nerve regeneration in rats induced by transplantation of in vitro differentiated bone-marrow stromal cells. The European journal of neuroscience 2001, 14 (11) : 1771-1776
PubMed
2) Kuroda Y, Kitada M, Wakao S, et al : Unique multipotent cells in adult human mesenchymal cell populations. Proc Natl Acad Sci USA 2010, 107 (19) : 8639-8643
 
3) Katagiri H, Kushida Y, Nojima M, et al : A Distinct Subpopulation of Bone Marrow Mesenchymal Stern Cells, Muse Cells, Directly Commit to the Replacement of Liver Components. Am J Transplant 2015
 
4) Uchida H, Morita T, Niizuma K, et al : Transplantation of Unique Subpopulation of Fibroblasts, Muse Cells, Ameliorates Experimental Stroke Possibly via Robust Neuronal Differentiation. Stem cells 2016, 34 (1) : 160-173
PubMed
5) Gage FH : Mammalian neural stem cells. Science 2000, 287 (5457) : 1433-1438
PubMed
6) Weissman IL, Shizuru JA : The origins of the identification and isolation of hematopoietic stem cells, and their capability to induce donor-specific transplantation tolerance and treat autoimmune diseases. Blood 2008, 112 (9) : 3543-3553
PubMed
7) Shevinsky LH, Knowles BB, Damjanov I, Solter D : Monoclonal antibody to murine embryos defines a stage-specific embryonic antigen expressed on mouse embryos and human teratocarcinoma cells. Cell 1982, 30 (3) : 697-705
PubMed
8) Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al : Embryonic stem cell lines derived from human blastocysts. Science 1998, 282 (5391) : 1145-1147
PubMed
9) Wakao S, Kitada M, Kuroda Y, et al : Multilineage-differentiating stress-enduring (Muse) cells are a primary source of induced pluripotent stem cells in human fibroblasts. Proc Natl Acad Sci U S A 2011, 108 (24) : 9875-9880
PubMed
10) Ogura F, Wakao S, Kuroda Y, et al : Human adipose tissue possesses a unique population of pluripotent stem cells with nontumorigenic and low telomerase activities : potential implications in regenerative medicine. Stem CellS Dev 2014, 23 (7) : 717-728
PubMed
11) Tsuchiyama K, Wakao S, Kuroda Y, et al : Functional melanocytes are readily reprogrammable from multilineage-differentiating stress-enduring (muse) cells, distinct stem cells in human fibroblasts. J Invest Dermatol 2013, 133 (10) : 2425-2435
PubMed
12) Kuroda Y, Wakao S, Kitada M, et al : Isolation, culture and evaluation of multilineage-differentiating stress-enduring (Muse) cells. Nat Protoc 2013, 8 (7) : 1391-1415
PubMed
13) Yamauchi T, Kuroda Y, Morita T, et al : Therapeutic effects of human multilineage-differentiating stress enduring (MUSE) cell transplantation into infarct brain of mice. PLoS One 2015, 10 (3) : e0116009
PubMed
14) Kinoshita K, Kuno S, Ishimine H, et al : Therapeutic Potential of Adipose-Derived SSEA-3-Positive Muse Cells for Treating Diabetic Skin Ulcers. Stem cells translational medicine 2015
 
15) Phinney DG, Prockop DJ : Concise review : mesenchymal stem/multipotent stromal cells : the state of transdifferentiation and modes of tissue repair-current views. Stem cells 2007, 25 (11) : 2896-2902
PubMed
16) Lee JS, Hong JM, Moon GJ, et al : A long-terln follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke. Stem cells 2010, 28 (6) : 1099-1106
PubMed
P.28 掲載の参考文献
1) Lindvall O, Kokaia Z. Stem cell research in stroke : how far from the clinic? Stroke. 42 : 2369-2375, 2011
PubMed
2) George PM, Steinberg GK. Novel Stroke Therapeutics : Unraveling Stroke Pathophysiology and Its Impact on Clinical Treatments. Neuron 87 : 297-309, 2015
PubMed
3) Onteniente B, Polentes J. Regenerative medicine for stroke-are we there yet? Cerebrovasc Dis 31 : 544-551, 2011
PubMed
4) Rosado-de-Castro PH1, Pimentel-Coelho PM, da Fonseca LM, de Freitas GR, Mendez-Otero R. The rise of cell therapy trials for stroke : review of published and registered studies. Stem Cells Dev 22 : 2095-2111, 2013
 
5) De Feo D, Merlini A, Laterza C, Martino G. Neural stem cell transplantation in central nervous system disorders : from cell replacement to neuroprotection. Curr Opin Neurol 25 : 322-333, 2012
PubMed
6) Boltze J, Arnold A, Walczak P, Jolkkonen J, Cui L, Wagner DC. The Dark Side of the Force-Constraints and Complications of Cell Therapies for Stroke. Front Neurol 6 : 155, 2015
PubMed
7) 金村米博. 中枢神経疾患に対する細胞移植療法を用いた再生治療. 脳神経外科 39 : 5-23, 2011
 
8) Okano H, Yamanaka S. iPS cell technologies : significance and applications to CNS regeneration and disease. Mol Brain 7 : 22, 2014
PubMed
9) Jeong H, Yim HW, Cho YS, Kim YI, Jeong SN, Kim HB, Oh IH. Efficacy and safety of stem cell therapies for patients with stroke : a systematic review and single arm meta-analysis. Int J Stem Cells 7 : 63-69, 2014
 
10) Cao W, Li P. Effectiveness and Safety of Autologous Bone Marrow Stromal Cells Transplantation After Ischemic Stroke : A Meta-Analysis. Med Sci Monit 21 : 2190-2195, 2015
PubMed
11) Prasad K, Sharma A, Garg A, Mohanty S, Bhatnagar S, Johri S, Singh KK, Nair V, Sarkar RS, Gorthi SP, Hassan KM, Prabhakar S, Marwaha N, Khandelwal N, Misra UK, Kalita J, Nityanand S ; InveST Study Group. Intravenous autologous bone rnarrow mononuclear stem cell therapy for ischemic stroke : a multicentric, randomized trial. Stroke 45 : 3618-3624, 2014
 
12) Oki K, Tatarishvili J, Wood J, Koch P, Wattananit S, Mine Y, Monni E, Tornero D, Ahlenius H, Ladewig J, Brustle O, Lindvall O, Kokaia Z. Human-induced pluripotent stem cells form functional neurons and improve recovery after grafting in stroke-damaged brain. Stem Cells 30 : 1120-1133, 2012
PubMed
13) Yuan T, Liao W, Feng NH, Lou YL, Niu X, Zhang AJ, Wang Y, Deng ZF. Human induced pluripotent stem cell-derived neural stem cells survive, migrate, differentiate, and improve neurologic function in a rat model of middle cerebral artery occlusion. Stem Cell Res Ther 4 : 73, 2013
 
P.35 掲載の参考文献
1) Takahashi K, Tanabe K, Ohnuki M, et al : Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007 ; 131 : 861-872
PubMed
2) Uccelli A, Moretta L, Pistoia V : Mesenchymal stem cells in health and disease. Nat Rev Immuno12008 ; 8 : 726-736
PubMed
3) Si-Tayeb K, Noto FK, Nagaoka M, et al : Highly ef6cient generation of human hepatocyte-like cel! s from induced pluripotent stem cells. Hepatology 2010 ; 51 : 297-305
 
4) Miyajima A, Tanaka M, Itoh T : Stem/progenitor cells in liver development, homeostasis, regeneration, and reprogramming. Cell Stem Cell 2014 ; 14 : 561-574
PubMed
5) Espejel S, Roll GR, McLaughlin KJ, et al : Induced pluripotent stern cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice. J Clin Invest 2010 ; 120 : 3120-3126
 
6) Yusa K, Rashid ST, Strick-Marchand H, et al : Targeted gene correction of alpha1-antitrypsin deficiency in induced pluripotent stem cells. Nature 2011 ; 478 : 391-394
PubMed
7) van Poll D, Parekkadan B, Cho CH, et al : Mesenchymal stem cell-derived molecules directly modulate hepatocellular death and regeneration in vitro and in vivo. Hepatology 2008 ; 47 : 1634-1643
PubMed
8) Terai S, Tanimoto H, Maeda M, et al : Timeline for development of autologous bone marrow infusion (ABMi) therapy and perspective for future stem cell therapy. J Gastroenterol 2012 ; 47 : 491-497
PubMed
9) Yi HG, Yahng SA, Kim I, et al : Allogeneic clonal mesenchymal stem cell therapy for refractory graft-versus-host disease to standard treatment : a phase I study. Korean J Physiol Pharmacol 2016 ; 20 : 63-67
PubMed
10) Morikawa S, Mabuchi Y, Kubota Y, et al : Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow. J Exp Med 2009 ; 206 : 2483-2496
PubMed
11) Sato T, Clevers H : SnapShot : Growing Organoids from Stem Cells. Cell 2015 ; 161 : 1700-e1.
PubMed
12) Sato T, Vries RG, SnipPert HJ, et al : Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 2009 ; 459 : 262-265
PubMed
13) Huch M, Boj SF, Clevers H : Lgr5 (+) liver stem cells, hepatic organoids and regenerative medicine. Regen Med 2013 ; 8 : 385-387
PubMed
14) Matano M, Date S, Shimokawa M, et al : Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids. Nat Med 2015 ; 21 : 256-262
PubMed
15) Takebe T, Sekine K, Enomura M, et al : Vascularized and functional human liver from an iPSC-derived organ bud transplant. Nature 2013 ; 499 : 481-484
PubMed
16) Takebe T, Enomura M, Yoshizawa E, et al : Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation, Cell Stem Cell 2015 ; 16 : 556-565
PubMed
17) Kobayashi T, Yamaguchi T, Hamanaka S, et al : Generation of rat pancreas in mouse by interspecific blastocyst injection of pluripotent stem cells. Cell 2010 ; 142 : 787-799
PubMed
18) Matsunari H, Nagashima H, Watanabe M, et al : Blastocyst complementation generates exogenic pancreas in vivo in apancreatic cloned pigs. Proc Natl Acad Sci U S A 2013 ; 110 : 4557-4562
PubMed
19) Rashid T, Kobayashi T, Nakauchi H. Revisiting the flight of Icarus : making human organs from PSCs with large animal chimeras. Cell Stem Cell 2014 ; 15 : 406-409
PubMed
20) Vogel G : STEM CELLS. NIH debates human-animal chimeras. Science 2015 ; 350 : 261-262
PubMed
21) Ohki T, Yamato M, Okano T, Yamamoto M : Regenerative medicine : tissue-engirleered cell sheet for the prevention of post-esophageal ESD stricture. Gastrointest Endosc Clin N Am 2014 ; 24 : 273-281
PubMed
22) Ohashi K, Yokoyama T, Yamato M, et al : Engineering functional two-and three-dimensional liver systems in vivo using hepatic tissue sheets. Nat Med 2007 ; 13 : 880-885
PubMed
23) Kawamura M, Miyagawa S, Miki K, et al : Feasibility, safety, and therapeutic efficacy of human induced pluripotent stem cell-derived cardiomyocyte sheets in a porcine ischemic cardiomyopathy model. Circulation 2012 ; 126 : S29-37.
 
24) Ott HC, Matthiesen TS, Goh SK, et al : Perfusion-decellularized matrix : using nature's platform to engineer a bioartificial heart. Nat Med 2008 ; 14 : 213-221
 
25) Ott HC, Clippinger B, Conrad C, et al : Regeneration and orthotopic transplantation of a bioartificial lung. Nat Med 2010 ; 16 : 927-933
PubMed
26) Macchiarini P, Jungebluth P, Go T, et al : Clinical transplantation of a tissue-engineered airway. Lancet 2008 ; 372 : 2023-2030
PubMed
27) Gonfiotti A, Jaus MO, Barale D, et al : The first tissue-engineered airway transplantation : 5-year follow-up results. Lancet 2014 ; 383 : 238-244
PubMed
28) Yagi H, Fukumitsu K, Fukuda K, Kitago M : Human-Scale Whole-Organ Bioengineering for Liver Transplantation : a Regenerative Medicine Approach. Cell Transplant 2013 : 22 : 231-242
PubMed
29) Wang Y, Bao J, Wu Q, et al : Method for perfusion decellularization of porcine whole liver and kidney for use as a scaffold for clinical-scale bioengineering engrafts. Xenotransplantation 2015 ; 22 : 48-61
PubMed
30) KolK, Peng L, Peloso A, et al : Bioengineered transplantable porcine livers with re-endothelialized vasculature. Biomaterials 2015 ; 40 : 72-79
 
P.40 掲載の参考文献
1) Eisner MD, Anthonisen N, Coultas D, et al : An official American Thoracic Society public policy statement : Novel risk factors and the global burden of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2010 ; 182 (5) : 693-718
PubMed
2) Massaro GD, Massaro D. Retinoic acid treatrnent abrogates elastase-induced pulmonary emphysema in rats. Nat Med 1997 ; 3 (6) : 675-677
 
3) Shigemura N, Sawa Y, Mizuno S, et al : Amelioration of pulmonary emphysema by in vivo gene transfection with hepatocyte growth factor in rats. Circulation 2005 ; 111 (11) : 1407-1414
PubMed
4) Sakamaki Y, Matsumoto K, Mizuno S, et al : Hepatocyte growth factor stimulates proliferation of respiratory epithelial cells during Postpneumonectomy compensatory lung growth in mice. Am J Respir Cell Mol Biol 2002 ; 26 (5) : 525-533
PubMed
5) Shigemura N, Sawa Y, Mizuno S, et al : Induction of compensatory lung growth in pulmonary emphysema improves surgical outcomes in rats. Am J Respir Crit Care Med 2005 ; 171 (11) : 1237-1245
PubMed
6) Yamada M, Kubo H, Kobayashi S, et al : Bone marrow-derived progenitor cells are important for lung repair after lipopolysaccharide-induced lung injury. J Immunol 2004 ; 172 (2) : 1266-1272
PubMed
7) Liu AR, Liu L, Chen S, et al : Activation of canonical wnt pathway promotes differentiation of mouse bone marrow-derived MSCs into type II alveolar epithelial cells, confers resistance to oxidative stress, and promotes their migration to injured lung tissue in vitro. J Cell Physiol 2013 ; 228 (6) : 1270-1283
PubMed
8) Shigemura N, Okumura M, Mizuno S, et al : Autologous transplantation of adipose tissue-derived stromal cells ameliorates pulmonary emphysema. Am J Transplant 2006 ; 6 (11) : 2592-2600
PubMed
9) Shigemura N, Okumura M, Mizuno S, et al : Lung tissue engineering technique with adipose stromal cells improves surgical outcome for pulmonary emphysema. Arn J Respir Crit Care Med 2006 ; 174 (11) : 1199-1205
 
10) Hogan BL, Barkauskas CE, Chapman HA, et al : Repair and regeneration of the respiratory system : complexity, plasticity, and mechanisms of lung stem cell function. Cell Stem Cell 2014 ; 15 (2) : 123-138
PubMed
11) Weiss DJ, Casaburi R, Flannery R, et al : A placebo-controlled, randomized trial of mesenchymal stem cells in COPD. Chest 2013 ; 143 (6) : 1590-1598
PubMed
12) Gotoh S, Ito I, Nagasaki T, et al : Generation of alveolar epithelial spheroids via isolated progenitor cells from human pluripotent stem cells. Stem Cell Reports 2014 ; 3 (3) : 394-403
PubMed
13) Ghaedi M, Calle EA, Mendez JJ, et al : Human iPS cell-derived alveolar epithelium repopulates lung extracellular matrix. J Clin Invest 2013 ; 123 (11) : 4950-4962
PubMed
14) Ott HC, Clippinger B, Conrad C, et al : Regeneration and orthotopic transplantation of a bioartificial lung. Nat Med 2010 ; 16 (8) : 927-933
PubMed
P.43 掲載の参考文献
1) Shapiro AM, Lakey JR, Ryan EA, et al : Islet transplantation in seven patients with type l diabetes mellitus using aglucocorticoid-free immunosuppressive regimen. N Engl J Med 2000 ; 343 (4) : 230-238
 
2) Shapiro A, Ricordi C, Hering B, et al : International trial of the Edmonton protocol for islet transplantation. N Engl J Med 2006 ; 355 (13) : 1318-1330
PubMed
3) Saito T, Gotoh M, Satomi S, et al : Islet transplantation using donors after cardiac death : report of the Japan Islet Transplantation Registry. Transplantation 2010 ; 90 (7) : 740-747
PubMed
4) Anazawa T, Saito T, Goto M, et al : Long-term outcomes of clinical transplantation of pancreatic islets with uncontrolled donors after cardiac death : a multicenter experience in Japan. Transplant Proc 2014 ; 46 (6) : 1980-1984
PubMed
5) Hering B, Kandaswamy R, Ansite J, et al : Single-donor, marginal-dose islet transplantation in patients with type 1 diabetes. JAMA 2005 ; 293 (7) : 830-835
PubMed
6) D'Amour KA, Bang AG, Eliazer S, et al : Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol 2006 ; 24 (11) : 1392-1401
 
7) Alipio Z, Liao W, Roemer EJ, et al : Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stem (iPS) -derived pancreatic beta-like cells. Proc Natl Acad Sci USA 2010 ; 107 (30) : 13426-13431
PubMed
8) Zhou Q, Brown J, Kanarek A, et al : In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 2008 ; 455 (7213) : 627-632
PubMed
9) Pagliuca FW, Millman JR, Gurtler M, et al : Generation of functional human pancreaticβcells in vitro. Cell 2014 ; 159 (2) : 428-439
 
10) Rezania A, Bruin JE, Arora P, et al : Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells. Nat Biotechnol 2014 ; 32 (11) : 1121-1133
PubMed
11) Luan NM, Iwata H : Long-term allogeneic islet graft survival in prevascularized subcutaneous sites without immunosuppressive treatment. Am J Transplant 2014 ; 14 (7) : 1533-1542
PubMed
P.46 掲載の参考文献
1) Kojima K Bonassar LJ, Roy AK, et al : Autologous tissue-engineered trachea with sheep nasal chondrocytes. J Thorac Cardiovasc Surg 2002 ; 123 : 1177-1184
PubMed
2) Teramachi M, Kiyotani T, Takimoto Y, et al : A new porous tracheal prosthesis sealed with collagen sponge. ASAIO J 1995 ; 41 : 306-310
 
3) Nakamura T, Teramachi M, Sekine T, et al : Artificial trachea and long term following in carinal reconstruction in dogs. Int J Artificial Organs 2000 ; 23 : 718-724
 
4) Omori K, Tada Y, Suzuki T, et al : Clinical application of in situ tissue engineering using a scaffolding technique for reconstruction of the larynx and trachea. Ann Otol Rhinol Laryngol 2008 ; 117 : 673-678
PubMed
5) Macchiarini P, Jungebluth P, Go T, et al : Clinical transplantation of a tissue-engineered airway. Lancet 2008 ; 372 : 2023-2030
PubMed
6) Kanemaru S, Nakamura T, Omori K, et al : Regeneration of mastoid air cells in clinical applications by in situ tissue engineering. The Laryngoscope 2005 ; 115 : 253-258
PubMed
7) Yaguchi Y, Wada K, Kojima H, et al : Middle Ear Mucosa Regeneration by Grafting of Artificial Mucosa. Acta Otolaryngol 2007 ; 127 : 1038-1044
PubMed
8) Yaguchi Y, Yamamoto K, Kojima H, et al : Middle ear mucosal regeneration with three-dimensionally tissue-engineered autologous middle ear cell sheets in rabbit model. J Tissue Eng Regen Med 2013, doi 10. 1002/term. 1790.
 
9) Yamamoto K, Yamato M, Kojima H, et al : The effect of transplantation of nasal mucosal epithelial cell sheets after middle ear surgery in a rabbit model. Biomaterials 2015 ; 42 : 87-93
 
10) Hama T, Yamamoto K, Kojima H, et al : Autologous human nasal epithelial cell sheet using temperature-responsive culture insert for transplantation after middle ear surgery. J Tissue Eng Regen Med 2015, doi 10. 1002/term.
 
11) Matsumoto M, Nakagawa T, Higashi T, et al : Innervation of stem cell-derived neurons into auditory epithelia of mice. Neuroreport 2005 ; 16 : 787-790
PubMed
12) Nakagawa T, Sakamoto T, Hiraumi H, et al : Topical insulin-like growth factor l treatment using gelatin hydrogels for glucocorticoid-resistant sudden sensorineural hearing loss : a prospective clinical trial. BMC Med 2010 ; 8 : 76
 
13) Sekiya T, Holley MC, Hashido K, et al : Cells transplanted onto the surface of the glial scar reveal hidden potential for functional neural regeneration. PNAS 2015 ; 112 : E3431-3440
 
14) Oshima K, Shin K, Diensthuber M, et al : Mechanosensitive Hair Cell-like Cells from Embyonic and Induced Pluripotent Stem Cells. Cell 2010 ; 141 : 704-716
 
15) Chen W, Jongkamonwiwat N, Abbas L, et al : Restoration of auditory evoked responses by human ES-cell-derived otic progenitors. Nature 2012 ; 490 : 278-282
PubMed
16) Koehler KR, Mikosz AM, Molosh AI, et al : Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture. Nature 2013 ; 500 : 217-21
PubMed
P.50 掲載の参考文献
1) Reynolds BA, Weiss S : Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 1992 ; 255 : 1707-1710
PubMed
2) Ogawa Y, Sawamoto K, Miyata T, et al : Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats. J Neurosci Res 2002 ; 69 : 925-933
PubMed
3) Iwanami A, Kaneko S, Nakamura M, et al : Transplantation of human neural stem cells for spinal cord injury in primates. J Neurosci Res 2005 ; 80 : 182-190
PubMed
4) McDonald JW, Liu XZ, Qu Y, Liu S, et al : Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord. Nat Med 1999 ; 5 : 1410-1412
PubMed
5) Okada Y, Matsumoto A, Shimazaki T, et al : Spatiotemporal recapitulation of central nervous system development by murine embryonic stem cell-derived neural stem/progenitor cells. Stem Cells 2008 ; 26 : 3086-3098
PubMed
6) Kumagai G, Okada Y, Yamane J, et al : Roles of ES cell-derived gliogenic neural stem/progenitor cells in functional recovery after spinal cord injury. PLoS One 2009 ; 4 : e7706
PubMed
7) Takahashi K, Yamanaka S : Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006 ; 126 : 663-676
PubMed
8) Takahashi K, Tanabe K, Ohnuki M, et al l Induction of pluripotent stem cells from adult human fibroblasts by defined factors, Cell 2007 ; 131 (5) : 861-872
 
9) Tsuji O, Miura K, Okada Y, et al : Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury. Proc Natl Acad Sci U S A 2010 ; 107 : 12704-12709
PubMed
10) Nori S, Okada Y, Yasuda A, et al : Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice. Proc Natl Acad Sci USA 2011 ; 108 : 16825-16830
PubMed
11) Kobayashi Y, Okada Y, Itakura G, et al : Pre-evaluated safe human iPSC-derived neural stem cells promote functional recovery after spinal cord injury in common marmoset without tumorigenicity. PLoS One 2012 ; 7 : e52787
PubMed
12) Nori S, Okada Y, Nishimura S, et al : Long-term safety issues of iPSC-based cell therapy in a spinal cord injury model : oncogenic transformation with epithelial-mesenchymal transition. Stem Cell Reports 2015 ; 4 : 360-373
 
13) Okano H : Stem cell biology of the central nervous system. J Neurosci Res 2002 ; 69 : 698-707
PubMed
14) Nishiyama Y, Iwanami A, Kohyama J, et al : Safe and efficient method for cryopreservation of human induced pluripotent stem cell-derived neural stem and progenitor cells by a programmed freezer with a magnetic field. Neurosci Res 2016 [Epub ahead of print]
 
15) Sugai K, Nishimura S, Kato-Negishi M, et al : Neural stem/progenitor cell-laden microfibers promote transplant survival in a mouse transected spinal cord injury model. J Neurosci Res 2015 ; 93 : 1826-1838
 
P.54 掲載の参考文献
1) Cotsarelis G, Cheng SZ, Dong G, et al : Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate : implications on epithelial stem cells. Cell 1989 ; 57 : 201-209
PubMed
2) Nishida K. Tissue engineering of the cornea. Cornea 2003 ; 22 : S28-S34
PubMed
3) Ilari L, Daya SM : Long-term outcomes of keratolimbal allograft for the treatment of severe ocular surface disorders. Ophthalmology 2002 ; 109 : 1278-1284
PubMed
4) Pellegrini G, Traverso CE, Franzi AT, et al : Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium. Lancet 1997 ; 349 : 990-993
PubMed
5) Tsai RJ, Li LM, Chen JK : Reconstruction of damaged corneas by transplantation of autologous limbal epithelial cells. N Engl J Med. 2000 ; 343 : 86-93
PubMed
6) Rama P, Bonini S, Lambiase A, et al : Autologous fibrin-cultured limbal stem cells permanently restore the corneal surface of patients with total limbal stem cell deficiency. 2001 ; 72 : 1478-1485
PubMed
7) Rama P, Matuska S, Paganoni G, et al : Limbal stem-cell therapy and long-term corneal regeneration. N Engl J Med 2010 ; 363 : 147-155
PubMed
8) Nishida K, Yamato M, Hayashida Y, et al : Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium. N Engl J Med 2004 ; 351 : 1187-1196
PubMed
P.57 掲載の参考文献
1) Rheinwald JG, Green, H : Serial cultivation of strains of human epidermal keratinocytes : The formation of keratinizing colonies from single cells. Cell 1975 ; 6 : 331-343
PubMed
2) Gallico GG 3rd, O'Connor NE, Compton CC, et al : Permanent coverage of large burn wounds with autologous cultured human epithelium. N Engl J Med 1984 ; 311 (7) : 448-451
 
3) Cuono C, Langdon R, McGuire J : Use of epidermal autografts and dermal allografts as skin replacement after burn injury. Lancet 1986 ; 1 (8490) : 1123-1124
PubMed
4) Hefton JM, Madden MR, Finkelstein JL, et al : Grafting of burn patients with allografts of cultured epidermal cells., Lancet 1983 ; 2 (8347) : 428-430
PubMed
5) 矢永博子, 有働幸弘, 田井良明 : 凍結同種培養表皮移植による小児熱傷および採皮創の治療. 形成外科 2002 ; 45 : 619-627
 
6) Yannas IV, Burke JF : Design of an artificial skin. 1. Basic design principles. J Biomed Mater Res. 14 : 65-81, 1980.
PubMed
7) Matsuda K, Suzuki S, Isshiki N. et al : Re-freeze-dried artificial skin. Biomaterials 1993 ; 14 : 1030-1035
PubMed
8) Koide M, Osaki K, Konishi J, et al : A new type of biomaterial for artificial skin : dehydrothermally crosslinked composites of fibrillar and denatured collagens. J Biomed Mater Res 1993 ; 27 : 79-87
 
9) 照喜納光信, 藤岡宏幸, 牧野健, ほか : 人工真皮を用いた指尖部損傷の治療経験. 中部日本整災会誌 2002 ; 45 : 1011-1012
 
10) Morimoto N, Yoshimura, K, Niimi, M, et al : Novel Collagen/Gelatin Scaffold With Sustained Release of Basic Fibroblast Growth Factor : clinical trial for chronic skin ulcers. Tissue Eng Part A 2013 ; 19 (17-18) : 1931-1940
 
11) Kuroyanagi Y, Yamada N, Yamashita R, Uchinuma E : Tissue-engineered product : allogeneic cultured dermal substitute composed of spongy collagen with fibroblasts. Artif Organs 2001 ; 25 : 180-186
PubMed
12) Bell E Ehrlich HP, Buttle DJ, Nakatsuji T et al : Living tissue formed in vitro and accepted as skin-equivalent tissue of full thickness. Science 1981 ; 211 : 1052-1054
PubMed
P.60 掲載の参考文献
1) Osafune K, Takasato M, Kispert A, et al : Identifical of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay. Development 2006 ; 133 : 151-161
 
2) Bohle A, Muller GA, Wehrmann M, et al : Pathogenesis of chronic renal failure in the primary glomerulopathies, renal vasculopathies, and chronic interstitial nephritides. Kidney Int Suppl 1996 ; 54 : S2-S9
PubMed
3) Mae S, Shono A, Shiota F et al : Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells. Nat Commun 2013 ; 4 : 1367
PubMed
4) Taguchi A, Kaku Y, Ohmori T, et al : Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells. Cell Stem Cell 2014 ; 14 : 53-67
PubMed
5) Sharmin S, Taguchi A, Kaku Y, et al : Human induced pluripotent stem cell-derived podocytes mature into vascularized glomeruli upon experimental transplantation. J Am Soc Nephrol 2015 [Epubahead of print]
 
6) Takebe T, Enomura M, Yoshizawa E, et al : Vascularized and cornplex organ buds from diverse tissues via mesenchymal cell-driven condensation. Cell Stem Cell 2015 ; 16 : 556-565
PubMed
7) Takasato M, Er PX, Chiu HS, et al : Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature 2015 ; 526 : 564-568
PubMed
8) Yokoo T, Ohashi T, Shen JS, et al : Human mesenchymal stem cells in rodent whole embryo cul-ture are reprogrammed to contribute kidney tissues. Proc Natl Acad Sci USA 2005 ; 102 : 3296-3300
 
9) Parazova DA, Oosterhuis NR, Gremmels H, et al : Cell-based therapies for experimental chronic kidney disease : a systematic review and meta-analysis. Dis Models Mech 2015 ; 8 : 281-293
 
10) Ninichuk V, Gross O, Segerer S, et al : Multipotent mesenchymal stem cells reduce interstitial fibrosis but do not delay progression of chronic kidney disease in collagen4A3-deficient mice. Kidney Int 2006 ; 70 : 121-129
 
11) Choi S, Park M, Kim J, et al : The role of mesenchymal stem cells in the functional improvement of chronic renal failure. Stem Cells Dev 2009 ; 18 : 521-530
PubMed
12) Mizuno S, Matsumoto K, Nakamura T : Hepatocyte growth factor suppresses interstitial fibrosis in a mouse model of obstructive nephropathy. Kidney Int 2001 ; 59 : 1304-1314
 
13) Sugiura T, Takahashi S, Sano K, et al : Pharmacokinetic modeling of hepatocyte growth factor in experimental animals and humans. Journal of Pharmaceutical Sciences 2013 ; 102 : 237-249
PubMed
P.64 掲載の参考文献
1) Hegedus Z. The rebuilding of the alveolar processes by bone transplantation. Dental Cosmos 1923 ; 65 : 736-742
 
2) Seo BM, Miura M, Gronthos S, et at : Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet 2004 ; 364 : 149-155
 
3) Iwata T, Yamato M, Ishikawa I, Ando T, Okano T. Tissue engineering in periodontal tissue. Anatomical record 2014 ; 297 : 16-25
 
4) Dominici M, Le Blanc K, Mueller I, et al : Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006 ; 8 : 315-317
PubMed
5) Iwata T, Washio K, Yoshida T, et al : Cell sheet engineering and its apPlication for periodontal regeneration. J Tissue Eng Regen Med 2015 ; 9 : 343-356
PubMed
6) Kitarnura M, Akamatsu M, Kawanami M, et al : Randomized Placebo-Controlled and Controlled Non-Inferiority Phase III Trials Comparing Trafermin, a Recombinant Human Fibroblast Growth Factor 2, and Enamel Matrix Derivative in Periodontal Regeneration in Intrabony Defects. J Bone Miner Res 2015.
 

書評

最近チェックした商品履歴

Loading...