腫瘍病理鑑別診断アトラス  食道癌 第2版

出版社: 文光堂
著者:
発行日: 2021-08-30
分野: 臨床医学:基礎  >  臨床病理学
ISBN: 9784830622595
シリーズ: 腫瘍病理鑑別診断アトラス
電子書籍版: 2021-08-30 (第2版第1刷)
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腫瘍病理鑑別診断アトラスシリーズ「食道癌」,待望の第2版.2012年の初版発行から約10年,2019年にはWHO分類第5版が発行されるなど,食道癌の臨床・病理を取り巻く環境は日々変化している.そうした状況を踏まえて,今回,食道病理のエキスパートが精選した病理写真とともに,定義や概念,診断上の要点を解説.食道癌病理診断の標準化を図りつつ鑑別ポイントをも網羅し,さらに,臨床との連携では欠かせない内視鏡診断や治療法のトピックもアップデータした.食道癌病理診断において即戦力となる,「痒い所に手が届く」座右の書.

目次

  • 第1部 検鏡前の確認事項
     I.取扱い規約組織学的分類とWHO組織分類
      1.取扱い規約分類,WHO分類を理解する上で知っておきたい基礎知識
      2.食道癌取扱い規約の変遷
      3.WHO組織分類の変遷
      4.上皮内腫瘍に関する取扱い規約分類とWHO分類の比較
     II.病理標本の取扱い方―標本整理・固定から切り出しまで
      1.手術切除標本の取扱い
      2.内視鏡的切除標本の取扱い
      3.食道癌の肉眼型(病型分類)と肉眼観察
     III.食道の解剖学・組織学
      1.解剖
      2.組織

    第2部 組織型と診断の実際
     I.主に扁平上皮領域に発生する病変
      1.良性上皮性腫瘍・腫瘍様病変
      2.扁平上皮内腫瘍
      3.上皮性悪性腫瘍
      (1)扁平上皮癌
      (2)類基底細胞扁平上皮癌
      (3)癌肉腫
      (4)腺扁平上皮癌,粘表皮癌
      (5)腺様囊胞癌およびその他の唾液腺型腫瘍
      (6)神経内分泌腫瘍
      (7)未分化癌
      4.非上皮性腫瘍・腫瘍様病変
      (1)顆粒細胞腫を含む神経性腫瘍,平滑筋腫,GIST,血管性腫瘍
      (2)食道悪性黒色腫と食道メラノサイトーシス
      (3)その他の食道非上皮性腫瘍・腫瘍様病変
      5.他臓器腫瘍の食道への浸潤・転移
     II.主に食道胃接合部に発生する病変
      1.Barrett食道,腺系異型上皮
      2.腺癌
      3.逆流性食道炎および関連非腫瘍性病変

    第3部 鑑別ポイント
     I.生検診断の鑑別ポイント
      1.炎症等に伴う異型と腫瘍性病変の鑑別
      2.治療後の生検標本の診断と鑑別
     II.切除標本診断の鑑別ポイント
      1.壁深達度の判定
      2.脈管侵襲の判定
      3.浸潤形式の判定

    第4部 臨床との連携
     I.食道内視鏡診断の進歩および病理との対応
      1.食道内視鏡診断学の解説(拡大内視鏡を除く)
      2.拡大内視鏡および超拡大内視鏡
     II.食道癌治療
      1.食道癌診療ガイドラインの解説
      2.食道癌内視鏡治療および外科治療(治療適応を含めて)
      3.食道癌薬物療法・放射線療法の解説
     III.病理診断報告書の記載
      1.生検検体の病理所見の記載
      2.内視鏡的切除検体の病理所見の記載
      3.手術検体の病理所見の記載
      4.治療効果の組織学的効果判定

この書籍の参考文献

参考文献のリンクは、リンク先の都合等により正しく表示されない場合がありますので、あらかじめご了承下さい。

本参考文献は電子書籍掲載内容を元にしております。

第1部 検鏡前の確認事項

P.7 掲載の参考文献
1) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版, 金原出版, 2015
2) WHO Classification of Tumours Editorial Board (ed) : WHO Classification of Tumours of the Digestive System, 5th ed, World Health Organization, 2019
3) Tachimori Y, Ozawa S, Numasaki H et al : Comprehensive registry of esophageal cancer in Japan, 2012. Esophagus 2019, 16 : 221-245
4) 日本胃癌学会 (編) : 胃癌取扱い規約, 第15版, 金原出版, 2017
5) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第2版, 金原出版, 1972
6) 食道疾患研究会 (編) : 臨床・病理 食道癌取扱い規約, 第8版, 金原出版, 1992
7) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第10版, 金原出版, 2007
8) Hamilton SR, Aaltonen LA, (ed) : World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Digestive System. 3rd ed, Lyon : IARC Press, 2000
9) Oota K, Sobin LH, ed : Histological typing of gastric and oesophageal tumours. Geneva, World Health Organization, 1977
10) Watanabe H, Jass JR, Sobin LH, (ed) : Histological typing of oesophageal and gastric tumours, 2nd ed, Berlin, Springer-Verlag, 1990
11) Bosman FT, Carneiro F, Hruban RH et al (ed) : WHO Classification of Tumours of the Digestive System, 4th ed, Lyon, International Agency for Research on Cancer, 2010
12) Bang YJ, Van Cutsem E, Feyereislova A et al : Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA) : a phase 3, open-label, randomised controlled trial. Lancet 2010, 376 : 687-697
13) Schlemper RJ, Dawsey SM, Itabashi M et al : Differences in diagnostic criteria for esophageal squamous cell carcinoma between Japanese and Western pathologists. Cancer 2000, 88 : 996-1006
14) Dixon MF : Gastrointestinal epithelial neoplasia : Vienna revisited. Gut 2002, 51 : 130-131
P.13 掲載の参考文献
1) 河内洋, 小池盛雄 : 食道癌切除標本整理のKnack & Pitfalls. 幕内雅敏 (監), 幕内博康 (編) : 食道外科の要点と盲点, 文光堂, 2003, 360-363
2) 秋山洋, 阿曽弘一, 牛山孝樹 ほか : 食道癌剔出標本の取扱いと収縮率. 日外会誌 1968, 69 : 1633-1637
3) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版, 金原出版, 2015
4) 二村聡 : 消化管切除標本の取り扱いとマクロ写真撮影について-基本的な作法を中心に-. 胃と腸 2010, 45 : 151-162
5) 二村聡 : 切除標本の取り扱いとマクロ写真撮影-消化管画像診断に必要な病理標本の取り扱いの基本手順-. 胃と腸 2016, 51 : 1176-1184
P.19 掲載の参考文献
1) 日本食道学会 (編) : 食道癌診療ガイドライン, 2017年版, 金原出版, 2017
2) 根本哲生, 門馬久美子, 伊東干城ほか : 食道癌内視鏡切除検体の取り扱い-特に多分割検体について-. 病理と臨床 2007, 25 : 664-671
3) Oyama T, Monma K : A new classification of magnified endoscopy for superficial esophageal squamous cell carcinoma. Esophagus 2011, 8 : 247-251
4) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版, 金原出版, 2015
5) 藤田昌宏, 佐藤利宏, 藤田裕美ほか : 食道ESD切除症例の病理学的検索成績. 胃と腸 2009, 44 : 345-358
6) Takubo K, Sasajima K, Yamashita K et al : Double muscularis mucosae in Barrett's esophagus. Huma Pathol 1991, 22 : 1158-1161
7) Aida J, Vieth M, Ell C et al : Palisade vessels as a new histologic marker of esophageal origin in ER specimens from columnar-lined esophagus. Am J Surg Pathol 2011, 35 : 1140-1145
8) Biddlestone LR, Barham CP, Wilkinson SP et al : The histopathology of treated Barrett's esophagus : squamous reepithelialization after acid suppression and laser and photodynamic therapy. Am J Surg Pathol 1998, 22 : 239-245
P.25 掲載の参考文献
1) 河内洋 : 消化器癌外科切除材料の取り扱いと肉眼診断, 食道 (2) 肉眼診断. 臨牀消化器内科 2008, 23 : 265-272
2) Watanabe M, Tachimori Y, Oyama T et al : Comprehensive registry of esophageal cancer in Japan, 2013. Esophagus 2021, 18 : 1-24
3) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版. 金原出版, 2015
4) 日本食道疾患研究会 (編) : 臨床・病理 食道癌取扱い規約, 第9版. 金原出版, 1999
5) 門馬久美子, 吉田操, 山田義也 他 : 粘膜下腫瘍様の形態を示した食道表在癌-臨床および画像的特徴, 鑑別診断. 胃と腸 2003, 38 : 1505-1518
6) 渡辺英伸, 多田哲也, 岩渕三哉他 : 病理からみた早期食道癌の定義と肉眼診断. 胃と腸 1990, 25 : 1075-1086
7) 吉田操, 室井正彦, 門馬久美子 他 : 食道m, sm癌の質的診断ならびに鑑別診断-内視鏡の立場から. 胃と腸 1990, 25 : 1059-1066
8) 井手博子, 村田洋子, 奥島憲彦 他 : 表在性食道癌肉眼分類の新しい提案-病理の立場から. 胃と腸 1987, 22 : 1369-1376
9) 幕内博康, 三富利夫, 田島知郎 他 : 内視鏡による食道m癌・sm癌の質的診断と鑑別診断. 胃と腸 1990, 25 : 1051-1058
10) 海上雅光, 八巻悟郎, 鶴丸昌彦 : 肉眼像からみた食道表在癌の深達度の読み方. 胃と腸 1992, 27 : 139-155
11) Participants in the Paris Workshop. The Paris endoscopic classification of superficial neoplastic lesions : esophagus, stomach, and colon : November 30 to December 1, 2002. Gastrointest Endosc 2003, 58 (6 Suppl) : S3-S43
P.31 掲載の参考文献
1) 日本胃癌学会 (編) : 胃癌取扱い規約, 第15版, 金原出版, 2017
2) 日本食道学会 (編) : 食道癌取扱い規約, 第11版, 金原出版, 2015
3) Siewert JR, Holscher AH, Becker K et al : [Cardia cancer : attempt at a therapeutically relevant classification]. Chirurg 1987, 58 : 25-32
4) Nakanishi Y, Saka M, Eguchi T et al : Distribution and significance of the oesophageal and gastric cardiac mucosae : a study of 131 operation specimens. Histopathology 2007, 51 : 515-519
5) 下田忠和 : 食道胃接合部癌の臨床病理. 病理と臨床 2011, 29 : 939-951
6) Mizutani H, Ono S, Ushiku T et al : Transparency-enhancing technology allows three-dimensional assessment of gastrointestinal mucosa : A porcine model. Pathol Int 2018, 68 : 102-108
7) Meyer GW, Austin RM, Brady CE 3rd et al : Muscle anatomy of the human esophagus. J Clin Gastroenterol 1986, 8 : 131-134

第2部 組織型と診断の実際

P.37 掲載の参考文献
1) Thurberg BL, Duray PH, Odze RD : Polypoid dysplasia in Barrett's esophagus : a clinicopathologic, immunohistochemical, and molecular study of five cases. Hum Pathol 1999, 30 : 745-752
2) Kushima R, Vieth M, Mukaisho K et al : Pyloric gland adenoma arising in Barrett's esophagus with mucin immunohistochemical and molecular cytogenetic evaluation. Virchows Arch 2005, 446 : 537-541
3) 河合めぐみ, 浅野道雄, 小澤亭史ほか : 食道粘膜下導管腺腫 (submucosal gland duct adenoma) の1例. 胃と腸 2008, 43 : 310-316
4) Takubo K, Esaki Y, Watanabe A et al : Adenoma accompanied by superficial squamous cell carcinoma of the esophagus. Cancer 1993, 71 : 2435-2438
5) Odze R, Antonioli D, Shocket D et al : Esophageal squamous papillomas. A clinicopathologic study of 38 lesions and analysis for human papillomavirus by the polymerase chain reaction. Am J Surg Pathol 1993, 17 : 803-812
6) Hizawa K, Iida M, Matsumoto T et al : Gastrointestinal manifestations of Cowden's disease. Report of four cases. J Clin Gastroenterol 1994, 18 : 13-18
7) Liaw D, Marsh DJ, Li J et al : Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat Genet 1997, 16 : 64-67
P.44 掲載の参考文献
1) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版, 金原出版, 2015
2) Takubo K, Fujii S : Oesophageal squamous dysplasia. WHO Classification of Tumours Digestive System Tumours 5th ed, IARC press, Lyon, 2019, 36-37
3) Bosman FT, Carneiro F, Hruban RH, et al (eds) : WHO Classification of Tumours of the Digestive System, 4th ed., IARC Press, Lyon, 2010
4) 河内洋 : 消化器腫瘍 I 新WHO分類のポイント 消化管編 食道. 病理と臨床 2020, 38 : 974-979
5) 食道疾患研究会 (編) : 臨床・病理 食道癌取扱い規約, 第9版, 金原出版, 1999
6) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第10版, 金原出版, 2007
7) 河内洋, 新井冨生 : 消化管 I-上部消化管-食道癌取扱い規約第11版の変更点. 病理と臨床 2016, 34 : 902-908
8) 藤井誠志 : 消化管粘膜内腫瘍の見方, 考え方, そのエビデンス 食道. 病理と臨床 2019, 37 : 692-702
9) 石原立, 有馬美和子, 飯塚敏郎, 他 : 食道癌に対するESD/EMRガイドライン. 日本消化器内視鏡学会雑誌 2020, 62 : 221-271
10) 島田英雄, 西隆之, 佐藤慎吉他. 多発食道癌, "まだら (多発ヨード不染域を有する) 食道" について. 腫瘍病理鑑別診断アトラス 食道癌, 文光堂, 2012, pp67-74
11) Kobayashi M, Kawachi H, Takizawa T, et al : p53 Mutation analysis of low-grade dysplasia and high-grade dysplasia/carcinoma in situ of the esophagus using laser capture microdissection. Oncology 2006, 71 : 237-245
12) Takemura K, Kawachi H, Eishi Y, et al : γ-Glutamylcyclotransferase as a novel immunohistochemical biomarker for the malignancy of esophageal squamous tumors. Hum Pathol 2014, 45 : 331-341
13) Sakamoto K, Aragaki T, Morita K, et al : Down-regulation of keratin 4 and keratin 13 expression in oral squamous cell carcinoma and epithelial dysplasia : a clue for histopathogenesis. Histopathology 2011, 58 : 531-542
14) Takashima M, Kawachi H, Yamaguchi T, et al : Reduced expression of cytokeratin 4 and 13 is a valuable marker for histologic grading of esophageal squamous intraepithelial neoplasia. J Med Dent Sci 2012, 59 : 17-28
15) 大倉康男, 中村恭一, 細井董三 他 : 生検による経過観察からみた食道の早期癌と "dysplasia" -癌組織発生と生検組織診断基準について. 胃と腸 1991, 26 : 141-152
P.59 掲載の参考文献
1) Global Burden of Disease Cancer Collaboration, Fitzmaurice C, Dicker D et al : The Global Burden of Cancer 2013. JAMA Oncol 2015, 1 : 505-527
2) Malhotra GK, Yanala U, Ravipati A et al : Global trends in esophageal cancer. J Surg Oncol 2017, 115 : 564-579
3) Wang SM, Abnet CC, Qiao YL : What have we learned from Linxian esophageal cancer etiological studies? Thorac Cancer 2019, 10 : 1036-1042
4) Shin A, Won YJ, Jung HK et al : Trends in incidence and survival of esophageal cancer in Korea : Analysis of the Korea Central Cancer Registry Database. J Gastroenterol Hepatol 2018, 33 : 1961-1968
5) Wang QL, Xie SH, Wahlin K et al : Global time trends in the incidence of esophageal squamous cell carcinoma. Clin Epidemiol 2018, 10 : 717-728
6) Lam KY, Law S, Tin L et al : The clinicopathological significance of p21 and p53 expression in esophageal squamous cell carcinoma : an analysis of 153 patients. Am J Gastroenterol 1999, 94 : 2060-2068
7) Lam AK : Introduction : Esophageal Adenocarcinoma : Updates of Current Status. Methods Mol Biol 2018, 1756 : 1-6
8) Xie SH, Lagergren J : Risk factors for oesophageal cancer. Best Pract Res Clin Gastroenterol 2018, 36-37 : 3-8
9) Abnet CC, Arnold M, Wei WQ : Epidemiology of Esophageal Squamous Cell Carcinoma. Gastroenterology 2018, 154 : 360-373
10) Muto M, Nakane M, Hitomi Y et al : Association between aldehyde dehydrogenase gene polymorphisms and the phenomenon of field cancerization in patients with head and neck cancer. Carcinogenesis 2002, 23 : 1759-1765
11) Akhtar S : Areca nut chewing and esophageal squamous-cell carcinoma risk in Asians : a meta-analysis of case-control studies. Cancer Causes Control 2013, 24 : 257-265
12) Mwachiro MM, Parker RK, Pritchett NR et al : Investigating tea temperature and content as risk factors for esophageal cancer in an endemic region of Western Kenya : Validation of a questionnaire and analysis of polycyclic aromatic hydrocarbon content. Cancer Epidemiol 2019, 60 : 60-66
13) He D, Zhang DK, Lam KY et al : Prevalence of HPV infection in esophageal squamous cell carcinoma in Chinese patients and its relationship to the p53 gene mutation. Int J Cancer 1997, 72 : 959-964
14) Talagala IA, Nawarathne M, Arambepola C : Novel risk factors for primary prevention of oesophageal carcinoma : a case-control study from Sri Lanka. BMC Cancer 2018, 18 : 1135
15) Donner I, Katainen R, Tanskanen T et al : Candidate susceptibility variants for esophageal squamous cell carcinoma. Genes Chromosomes Cancer 2017, 56 : 453-459
16) Ponds FA, Moonen A, Smout AJPM et al : Screening for dysplasia with Lugol chromoendoscopy in longstanding idiopathic achalasia. Am J Gastroenterol 2018, 113 : 855-862
17) Nasa M, Patil G, Sharma Z et al : Plummer-Vinson Syndrome with Simultaneous Mid-esophageal Growth. J Assoc Physicians India 2017, 65 : 96-97
18) Priante AV, Castilho EC, Kowalski LP : Second primary tumors in patients with head and neck cancer. Curr Oncol Rep 2011, 13 : 132-137
19) Dawsey SM, Lewin KJ, Wang GQ et al : Squamous esophageal histology and subsequent risk of squamous cell carcinoma of the esophagus. A prospective follow-up study from Linxian, China. Cancer 1994, 74 : 1686-1692
20) Wang GQ, Abnet CC, Shen Q et al : Histological precursors of oesophageal squamous cell carcinoma : results from a 13 year prospective follow up study in a high risk population. Gut 2005, 54 : 187-192
21) WHO Classification of Tumours Editorial Board WHO Classification of Tumours 5th Edition, Digestive System Tumours, World Health Organization, 2019
22) Okada N, Fujii S, Fujita T et al : The prognostic significance of the positive circumferential resection margin in pathologic T3 squamous cell carcinoma of the esophagus with or without neoadjuvant chemotherapy. Surgery 2016, 159 : 441-450
23) Stratton MR : Exploring the genomes of cancer cells : progress and promise. Science 2011, 331 : 1553-1558
24) Zhang L, Zhou Y, Cheng C et al : Genomic analyses reveal mutational signatures and frequently altered genes in esophageal squamous cell carcinoma. Am J Hum Genet 2015, 96 : 597-611
25) Hu N, Wang C, Ng D et al : Genomic characterization of esophageal squamous cell carcinoma from a high-risk population in China. Cancer Res 2009, 69 : 5908-5917
26) Song Y, Li L, Ou Y et al : Identification of genomic alterations in oesophageal squamous cell cancer. Nature 2014, 509 : 91-95
27) Shi ZZ, Liang JW, Zhan T et al : Genomic alterations with impact on survival in esophageal squamous cell carcinoma identified by array comparative genomic hybridization. Genes Chromosomes Cancer 2011, 50 : 518-526
28) Shi ZZ, Shang L, Jiang YY et al : Consistent and differential genetic aberrations between esophageal dysplasia and squamous cell carcinoma detected by array comparative genomic hybridization. Clin Cancer Res 2013, 19 : 5867-5878
29) Togashi Y, Arao T, Kato H et al : Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production. Oncotarget 2014, 5 : 2962-2973
30) Lin DC, Hao JJ, Nagata Y et al : Genomic and molecular characterization of esophageal squamous cell carcinoma. Nat Genet 2014, 46 : 467-473
31) Cheng C, Zhou Y, Li H et al : Whole-Genome Sequencing Reveals Diverse Models of Structural Variations in Esophageal Squamous Cell Carcinoma. Am J Hum Genet 2016, 98 : 256-274
32) Hu N, Kadota M, Liu H et al : Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer. Cancer Res 2016, 76 : 1714-1723
33) Qin HD, Liao XY, Chen YB et al : Genomic Characterization of Esophageal Squamous Cell Carcinoma Reveals Critical Genes Underlying Tumorigenesis and Poor Prognosis. Am J Hum Genet 2016, 98 : 709-727
34) Gao YB, Chen ZL, Li JG et al : Genetic landscape of esophageal squamous cell carcinoma. Nat Genet 2014, 46 : 1097-1102
35) Sawada G, Niida A, Uchi R et al : Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population. Gastroenterology 2016, 150 : 1171-1182
36) Cancer Genome Atlas Research Network, Analysis Working Group : Asan University, BC Cancer Agency, et al : Integrated genomic characterization of oesophageal carcinoma. Nature 2017, 541 : 169-175
37) Lima SC, Hernandez-Vargas H, Simao T et al : Identification of a DNA methylome signature of esophageal squamous cell carcinoma and potential epigenetic biomarkers. Epigenetics 2011, 6 : 1217-1227
38) Wang X, Wang J, Jia Y et al : Methylation decreases the Bin1 tumor suppressor in ESCC and restoration by decitabine inhibits the epithelial mesenchymal transition. Oncotarget 2017, 8 : 19661-19673
39) Chai AW, Cheung AK, Dai W et al : Metastasis-suppressing NID2, an epigenetically-silenced gene, in the pathogenesis of nasopharyngeal carcinoma and esophageal squamous cell carcinoma. Oncotarget 2016, 7 : 78859-78871
40) Deng J, Zhang J, Wang Ch et al : Methylation and expression of PTPN22 in esophageal squamous cell carcinoma. Oncotarget 2016, 7 : 64043-64052
41) Bao Y, Wang Q, Guo Y et al : PRSS8 methylation and its significance in esophageal squamous cell carcinoma. Oncotarget 2016, 7 : 28540-28555
42) Yang Y, Katz JP : KLF4 is downregulated but not mutated during human esophageal squamous cell carcinogenesis and has tumor stage-specific functions. Cancer Biol Ther 2016, 17 : 422-429
43) Li P, Liu X, Dong ZM et al : Epigenetic silencing of HIC1 promotes epithelial-mesenchymal transition and drives progression in esophageal squamous cell carcinoma. Oncotarget 2015, 6 : 38151-38165
44) Guo W, Dong Z, Cui J et al : Aberrant hypermethylation of RASSF2 in tumors and peripheral blood DNA as a biomarker for malignant progression and poor prognosis of esophageal squamous cell carcinoma. Clin Exp Metastasis 2016, 33 : 73-85
45) Kuroki T, Trapasso F, Yendamuri S et al : Promoter hypermethylation of RASSF1A in esophageal squamous cell carcinoma. Clin Cancer Res 2003, 9 : 1441-1445
46) Guo W, Wang C, Guo Y et al : RASSF5A, a candidate tumor suppressor, is epigenetically inactivated in esophageal squamous cell carcinoma. Clin Exp Metastasis 2015, 32 : 83-98
47) Lee S, Jiang P, Wang W et al : The decreased expression of protease-activated receptor 4 in esophageal squamous carcinoma. Neoplasma 2014, 61 : 546-552
48) Guo W, Zhang M, Shen S et al : Aberrant methylation and decreased expression of the TGF-β/Smad target gene FBXO32 in esophageal squamous cell carcinoma. Cancer 2014, 120 : 2412-2423
49) Smith E, Ruszkiewicz AR, Jamieson GG et al : IGFBP7 is associated with poor prognosis in oesophageal adenocarcinoma and is regulated by promoter DNA methylation. Br J Cancer 2014, 110 : 775-782
50) Yue D, Fan Q, Chen X et al : Epigenetic inactivation of SPINT2 is associated with tumor suppressive function in esophageal squamous cell carcinoma. Exp Cell Res 2014, 322 : 149-158
51) Choi GC, Li J, Wang Y et al : The metalloprotease ADAMTS8 displays antitumor properties through antagonizing EGFR-MEK-ERK signaling and is silenced in carcinomas by CpG methylation. Mol Cancer Res 2014, 12 : 228-238
52) Zhu YH, Fu L, Chen L et al : Downregulation of the novel tumor suppressor DIRAS1 predicts poor prognosis in esophageal squamous cell carcinoma. Cancer Res 2013, 73 : 2298-2309
53) Tong M, Chan KW, Bao JY et al : Rab25 is a tumor suppressor gene with antiangiogenic and anti-invasive activities in esophageal squamous cell carcinoma. Cancer Res 2012, 72 : 6024-6035
54) Ma S, Bao JYJ, Kwan PS et al : Identification of PTK6, via RNA sequencing analysis, as a suppressor of esophageal squamous cell carcinoma. Gastroenterology 2012, 143 : 675-686. e12
55) Ling ZQ, Li P, Ge MH et al : Hypermethylation-modulated down-regulation of CDH1 expression contributes to the progression of esophageal cancer. Int J Mol Med 2011, 27 : 625-635
56) Kong KL, Kwong DL, Fu L et al : Characterization of a candidate tumor suppressor gene uroplakin 1A in esophageal squamous cell carcinoma. Cancer Res 2010, 70 : 8832-8841
57) Guo M, Ren J, Brock MV et al : Promoter methylation of HIN-1 in the progression to esophageal squamous cancer. Epigenetics 2008, 3 : 336-341
58) Park HL, Kim MS, Yamashita K et al : DCC promoter hypermethylation in esophageal squamous cell carcinoma. Int J Cancer 2008, 122 : 2498-2502
59) Fu L, Qin YR, Xie D et al : Characterization of a novel tumor-suppressor gene PLC delta 1 at 3p22 in esophageal squamous cell carcinoma. Cancer Res 2007, 67 : 10720-10726
60) Tanaka K, Imoto I, Inoue J et al : Frequent methylation-associated silencing of a candidate tumor-suppressor, CRABP1, in esophageal squamous-cell carcinoma. Oncogene 2007, 26 : 6456-6468
61) Sonoda I, Imoto I, Inoue J et al : Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma. Cancer Res 2004, 64 : 3741-3747
62) Wang Y, Fang MZ, Liao J et al : Hypermethylation-associated inactivation of retinoic acid receptor beta in human esophageal squamous cell carcinoma. Clin Cancer Res 2003, 9 : 5257-5263
63) Ito T, Shimada Y, Hashimoto Y et al : Involvement of TSLC1 in progression of esophageal squamous cell carcinoma. Cancer Res 2003, 63 : 6320-6326
64) Kuroki T, Trapasso F, Yendamuri S et al : Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma. Cancer Res 2003, 63 : 3724-3728
65) Maesawa C, Tamura G, Nishizuka S et al : Inactivation of the CDKN2 gene by homozygous deletion and de novo methylation is associated with advanced stage esophageal squamous cell carcinoma. Cancer Res 1996, 56 : 3875-3878
66) Tokugawa T, Sugihara H, Tani T et al : Modes of silencing of p16 in development of esophageal squamous cell carcinoma. Cancer Res 2002, 62 : 4938-4944
67) Daigo Y, Nishiwaki T, Kawasoe T et al : Molecular cloning of a candidate tumor suppressor gene, DLC1, from chromosome 3p21.3. Cancer Res 1999, 59 : 1966-1972
68) Tanaka H, Shimada Y, Harada H et al : Methylation of the 5' CpG island of the FHIT gene is closely associated with transcriptional inactivation in esophageal squamous cell carcinomas. Cancer Res 1998, 58 : 3429-3434
69) Lawrence MS, Stojanov P, Mermel CH et al : Discovery and saturation analysis of cancer genes across 21 tumour types. Nature 2014, 505 : 495-501
70) Cancer Genome Atlas Research Network : Comprehensive genomic characterization of squamous cell lung cancers. Nature 2012, 489 : 519-525
71) Kawano H, Saeki H, Kitao H et al : Chromosomal instability associated with global DNA hypomethylation is associated with the initiation and progression of esophageal squamous cell carcinoma. Ann Surg Oncol 2014, 21 (Suppl 4) : S696-702
72) Baba Y, Watanabe M, Murata A et al : LINE-1 hypomethylation, DNA copy number alterations, and CDK6 amplification in esophageal squamous cell carcinoma. Clin Cancer Res 2014, 20 : 1114-1124
73) Liu F, Gu L, Cao Y et al : Aberrant overexpression of EZH2 and H3K27me3 serves as poor prognostic biomarker for esophageal squamous cell carcinoma patients. Biomarkers 2016, 21 : 80-90
74) Zhong X, Chen X, Guan X et al : Overexpression of G9a and MCM7 in oesophageal squamous cell carcinoma is associated with poor prognosis. Histopathology 2015, 66 : 192-200
75) He LR, Liu MZ, Li BK et al : Prognostic impact of H3K-27me3 expression on locoregional progression after chemoradiotherapy in esophageal squamous cell carcinoma. BMC Cancer 2009, 9 : 461
76) Tzao C, Tung HJ, Jin JS et al : Prognostic significance of global histone modifications in resected squamous cell carcinoma of the esophagus. Mod Pathol 2009, 22 : 252-260
77) Zhang K, Li L, Zhu M et al : Comparative analysis of histone H3 and H4 post-translational modifications of esophageal squamous cell carcinoma with different invasive capabilities. J Proteomics 2015, 112 : 180-189
78) Valente L, Nishikura K : ADAR gene family and A-to-I RNA editing : diverse roles in posttranscriptional gene regulation. Prog Nucleic Acid Res Mol Biol 2005, 79 : 299-338
79) Qin YR, Qiao JJ, Chan TH et al : Adenosine-to-inosine RNA editing mediated by ADARs in esophageal squamous cell carcinoma. Cancer Res 2014, 74 : 840-851
80) Yokoyama A, Kakiuchi N, Yoshizato T et al : Age-related remodelling of oesophageal epithelia by mutated cancer drivers. Nature 2019, 565 : 312-317
81) Rice TW, Ishwaran H, Hofstetter WL et al : Recommendations for pathologic staging (pTNM) of cancer of the esophagus and esophagogastric junction for the 8th edition AJCC/UICC staging manuals. Dis Esophagus 2016, 29 : 897-905
82) Shimada H, Nabeya Y, Okazumi S et al : Prediction of survival with squamous cell carcinoma antigen in patients with resectable esophageal squamous cell carcinoma. Surgery 2003, 133 : 486-494
83) Thompson SK, Ruszkiewicz AR, Jamieson GG et al : Improving the accuracy of TNM staging in esophageal cancer : a pathological review of resected specimens. Ann Surg Oncol 2008, 15 : 3447-3458
84) Chen SB, Weng HR, Wang G et al : Prognostic factors and outcome for patients with esophageal squamous cell carcinoma underwent surgical resection alone : evaluation of the seventh edition of the American Joint Committee on Cancer staging system for esophageal squamous cell carcinoma. J Thorac Oncol 2013, 8 : 495-501
85) Huang Q, Luo K, Chen C et al : Identification and Validation of Lymphovascular Invasion as a Prognostic and Staging Factor in Node-Negative Esophageal Squamous Cell Carcinoma. J Thorac Oncol 2016, 11 : 583-592
86) Wang S, Chen X, Fan J et al : Prognostic Significance of Lymphovascular Invasion for Thoracic Esophageal Squamous Cell Carcinoma. Ann Surg Oncol 2016, 23 : 4101-4109
87) Brucher BL, Stein HJ, Werner M et al : Lymphatic vessel invasion is an independent prognostic factor in patients with a primary resected tumor with esophageal squamous cell carcinoma. Cancer 2001, 92 : 2228-2233
88) Takubo K, Sasajima K, Yamashita K et al : Prognostic significance of intramural metastasis in patients with esophageal carcinoma. Cancer 1990, 65 : 1816-1819
89) Moon DH, Jeon JH, Yang HC et al : Intramural Metastasis as a Risk Factor for Recurrence in Esophageal Squamous Cell Carcinoma. Ann Thorac Surg 2018, 106 : 249-256
90) Chao YK, Yeh CJ, Chang HK et al : Impact of circumferential resection margin distance on locoregional recurrence and survival after chemoradiotherapy in esophageal squamous cell carcinoma. Ann Surg Oncol 2011, 18 : 529-534
91) Sung CO, Park CK, Kim SH : Classification of epithelial-mesenchymal transition phenotypes in esophageal squamous cell carcinoma is strongly associated with patient prognosis. Mod Pathol 2011, 24 : 1060-1068
92) Jesinghaus M, Boxberg M, Konukiewitz B et al : A Novel Grading System Based on Tumor Budding and Cell Nest Size Is a Strong Predictor of Patient Outcome in Esophageal Squamous Cell Carcinoma. Am J Surg Pathol 2017, 41 : 1112-1120
93) Enzinger PC, Mayer RJ : Esophageal cancer. N Engl J Med 2003, 349 : 2241-2252
94) Pennathur A, Gibson MK, Jobe BA et al : Oesophageal carcinoma. Lancet 2013, 381 : 400-412
95) di Pietro M, Canto MI, Fitzgerald RC : Endoscopic Management of Early Adenocarcinoma and Squamous Cell Carcinoma of the Esophagus : Screening, Diagnosis, and Therapy. Gastroenterology. 2018, 154 : 421-436
96) 大星章一, 下里幸雄, 板倉克明ほか : 癌放射線療法の病理 (1) 癌組織の治癒過程の組織学的追跡 (その1, その2). 医学のあゆみ 61 : 618-625, 665-671, 1967
97) Hatogai K, Fujii S, Kojima T et al : Prognostic significance of tumor regression grade for patients with esophageal squamous cell carcinoma after neoadjuvant chemotherapy followed by surgery. J Surg Oncol 2016, 113 : 390-396
98) Kadota T, Hatogai K, Yano T et al : Pathological tumor regression grade of metastatic tumors in lymph node predicts prognosis in esophageal cancer patients. Cancer Sci 2018, 109 : 2046-2055
99) Kadota T, Yano T, Fujita T et al : Submucosal Invasive Depth Predicts Lymph Node Metastasis and Poor Prognosis in Submucosal Invasive Esophageal Squamous Cell Carcinoma. Am J Clin Pathol 2017, 148 : 416-426
100) Okada N, Daiko H, Kanamori J et al : Impact of pathologically assessing extranodal extension in the thoracic field on the prognosis of esophageal squamous cell carcinoma. Surgery 2019, 165 : 1203-1210
P.67 掲載の参考文献
1) Bosman FT, Carneiro F, Hruban RH et al : WHO Classification of Tumours of the Digestive System, World Health Organization, 2010
2) 田久保海誉 : 食道の病理, 第2版, 総合医学社, 1996
3) 石黒伸吾 : 食道. 向井清, 真鍋俊明, 深山正久 (編) : 外科病理学, 第4版, 文光堂, 2006, 397-426
4) Takubo K, Mafune K, Tanaka Y et al : Basaloid-squamous carcinoma of the esophagus with marked deposition of basement membrane substance. Acta Pathol Jpn 1991, 41 : 59-64
5) Wain SL, KierR, Vollmer RT et al : Basaloid-squamous carcinoma of the tongue, hypopharynx and larynx : report of 10 cases. Hum Pathol 1986, 17 : 1158-1166
6) Epstein JI, Sears DL, Tucker RS et al : Carcinoma of the esophagus with adenoid cystic differentiation. Cancer 1984, 53 : 1131-1136
7) Tsang WY, Chan JK, Lee KC et al : Basaloid-squamous carcinoma of the upper aerodigestive tract and so-called adenoid cystic carcinoma of the oesophagus : the same tumour type? Histopathology 1991, 19 : 35-46
8) Sarbia M, Verreet P, Bittinger F et al : Basaloid squamous cell carcinoma of the esophagus : diagnosis and prognosis. Cancer 1997, 79 : 1871-1878
9) Ohashi K, Horiguchi S, Moriyama S et al : Superficial basaloid squamous carcinoma of the esophagus. A clinicopathological and immunohistochemical study of 12 cases. Pathol Res Pract 2003, 199 : 713-721
10) Abe K, Sasano H, Itakura Y et al : Basaloid-squamous carcinoma of the esophagus. A clinicopathologic, DNA ploidy, and immunohistochemical study of seven cases. Am J Surg Pathol 1996, 20 : 453-461
11) 大橋健一 : 類基底細胞癌と基底膜様物質, 病理形態学キーワード, 病理と臨床 2010, 28 (臨時増刊号) : 104-105
P.72 掲載の参考文献
1) Hamilton S, Aaltonen L : WHO Classification of Tumours : Pathology & Genetics Tumours of the Digestive System, IARC, 2000
2) 板橋正幸 : 癌肉腫. 下里幸雄 (編) : 取り扱い規約に沿った腫瘍鑑別診断アトラス 食道, 文光堂, 1994, 110-115
3) Wada H, Enomoto T, Fujita M et al : Molecular evidence that most but not all carcinosarcomas of the uterus are combination tumors. Cancer Res 1997, 57 : 5379-5385
4) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版, 金原出版, 2015
5) Schizas D, Mastoraki A, Bagias G et al : Carcinosarcomas of the esophagus : systematic review of a rare nosologic entity. J BUON 2018, 23 : 1432-1438
6) 中野徹, 小澤洋平, 直島君成ほか : 食道癌肉腫7症例の臨床病理学的検討. 日臨外会誌 2014, 75 : 1169-1174
7) 西田卓弘, 日高秀樹, 前原直樹ほか : 有茎性腫瘤を2個形成した食道癌肉腫の1例. 臨床外科 2011, 73 : 997-1000
P.77 掲載の参考文献
1) WHO Classification of Tumours Digestive System Tumours, 5th ed, IARC press, Lyon, 2019
2) 食道疾患研究会 (編) : 臨床・病理食道癌取扱い規約 第9版, 金原出版, 1999
3) 日本食道学会 (編) : 臨床・病理食道癌取扱い規約 第10版, 金原出版, 2007
4) 日本食道学会 (編) : 臨床・病理食道癌取扱い規約 第11版, 金原出版, 2015
5) 伊藤栄作, 赤澤直樹 : 腺扁平上皮癌と粘表皮癌. 田久保海誉, 大橋健一 (編) : 腫瘍病理鑑別診断アトラス食道癌, 文光堂, 2012, pp132-135
6) Watanabe M, Tachimori Y, Oyama T, et al : Comprehensive registry of esophageal cancer in Japan, 2013. Esophagus 18 : 1-24, 2021
7) 河内洋 : 食道癌の組織型と鑑別診断. 日本病理学会病理診断講習会委員会 (編) : 2019年度病理診断講習会ハンドアウト, 2019
8) 稲垣宏, 伊地知圭 : 粘表皮癌. 森永正二郎, 高田隆, 長尾俊孝 (編) : 腫瘍病理鑑別診断アトラス頭頸部腫瘍 I 唾液腺, 文光堂, 2015, pp23-31
9) Nie L, Li W, Wan L, et al : Submucosal gland neoplasms of the esophagus : an update and review. Esophagus 17 : 376-384, 2020
P.80 掲載の参考文献
1) 河内洋, 佐藤由紀子, 中野薫 : 唾液腺型食道腫瘍の臨床病理学的特徴. 胃と腸 54 : 1419-1426, 2019
2) 日本食道学会 (編) : 臨床・病理食道癌取扱い規約 第11版, 金原出版, 2015
3) WHO Classification of Tumours Digestive System Tumours, 5th ed, IARC press, Lyon, 2019
4) Tsang WY, Chan JK, Lee KC, et al : Basaloid-squamous carcinoma of the upper aerodigestive tract and so-called adenoid cystic carcinoma of the oesophagus : the same tumour type? Histopathology 19 : 35-46, 1991
5) 大橋健一 : 類基底細胞癌と腺様嚢胞癌. 腫瘍病理鑑別診断アトラス食道癌, 文光堂, 2012, pp120-125
6) Watanabe M, Tachimori Y, Oyama T, et al : Comprehensive registry of esophageal cancer in Japan, 2013. Esophagus 18 : 1-24, 2021
7) 駄阿勉 : 腺様嚢胞癌. 腫瘍病理鑑別診断アトラス頭頸部腫瘍 I 唾液腺腫瘍, 文光堂, 2015, pp32-37
8) Stenman G : Fusion oncogenes in salivary gland tumors : Molecular and clinical consequences. Head Neck Pathol 7 : S12-S19, 2013
9) Nie L, Li W, Wan L, et al : Submucosal gland neoplasms of the esophagus : an update and review. Esophagus 17 : 376-384, 2020
10) 河内洋 : 食道癌の組織型と鑑別診断. 日本病理学会病理診断講習会委員会 (編) : 2019年度病理診断講習会ハンドアウト, 2019
P.85 掲載の参考文献
1) Klimstra DS, Kloppel G, La Rosa S et al : Classification of neuroendocrine neoplasms of the digestive system. WHO Classification of Tumours Editorial Board (ed) : WHO Classification of Tumours Digestive System Tumours 5th Ed, World Health Organization, 2019, 16-22
2) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版, 金原出版, 2015
3) Soga J : Carcinoid tumors : A statistical analysis of a Japanese series of 3,126 reported and 1,180 autopsy cases. Acta Med Biol 1994, 42 : 87-102
4) Estrozi B, Bacchi CE : Neuroendocrine tumors involving the gastroenteropancreatic tract : a clinicopathological evaluation of 773 cases. Clinics (Sao Paulo) 2011, 66 : 1671-1675
5) 佐藤俊大, 小林正明, 五十川正人ほか : 内視鏡的に治療した食道カルチノイドの1例. Gastroenterol Endosc 2009, 51 : 3078-3084
6) Lim CS, Park SJ, Park MI et al : Successful endoscopic mucosal resection of a low esophageal carcinoid tumor. Clin Endosc 2013, 46 : 576-578
7) Yagi M, Abe Y, Sasaki Y, et al : Esophageal carcinoid tumor treated by endoscopic resection. Dig Endosc 2015, 27 : 527-530
8) 岩坪太郎, 石原立, 北村昌紀ほか : 食道神経内分泌細胞腫瘍の内視鏡診断. 胃と腸 2019, 54 : 1399-1408
9) Hoang MP, Hobbs CM, Sobin LH et al : Carcinoid tumor of the esophagus : a clinicopathologic study of four cases. Am J Surg Pathol 2002, 26 : 517-522
10) Tachimori Y, Ozawa S, Numasaki H, et al : Comprehensive registry of esophageal cancer in Japan, 2012. Esophagus 2019, 16 : 221-245
11) Egashira A, Morita M, Kumagai R et al : Neuroendocrine carcinoma of the esophagus : Clinicopathological and immunohistochemical features of 14 cases. PLoS One 2017, 12 : e0173501
12) 幕内博康, 鬼島宏 : 食道原発未分化型癌の診断と治療. 病理と臨床 2002, 20 : 479-488
13) 海崎泰治, 小上瑛也, 原季衣ほか : 消化管内分泌細胞腫瘍の病理学的特徴. 胃と腸 2017, 52 : 390-401
14) Sorbye H, Welin S, Langer SW et al : Predictive and prognostic factors for treatment and survival in 305 patients with advanced gastrointestinal neuroendocrine carcinoma (WHO G3) : the NORDIC NEC study. Ann Oncol 2013, 24 : 152-160
15) Tateishi R, Taniguchi H, Wada A et al : Argyrophil cells and melanocytes in esophageal mucosa. Arch Pathol 1974, 98 : 87-89
16) 田久保海誉, 本間尚子, 相田順子ほか : 食道小細胞癌の病態・診断・治療. 臨消内科 21 : 2006, 1377-1383
17) Maru DM, Khurana H, Rashid A et al : Retrospective study of clinicopathologic features and prognosis of high-grade neuroendocrine carcinoma of the esophagus. Am J Surg Pathol 2008, 32 : 1404-1411
18) Fujimasa K, Ohike N, Norose T et al : Frequent and Specific Involvement of Changes of the p16-RB Pathway in Esophageal Neuroendocrine Carcinoma. Anticancer Res 2019, 39 : 1927-1934
19) Ishida H, Kasajima A, Kamei T et al : SOX2 and Rb1 in esophageal small-cell carcinoma : their possible involvement in pathogenesis. Mod Pathol 2017, 30 : 660-671
P.89 掲載の参考文献
1) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版, 金原出版, 2015, 90
2) Kawachi H, Saito T : Undifferentiated carcinoma. WHO Classification of Tumours Editorial Board (ed) : WHO Classification of Tumours of the Digestive System Tumours, 5th ed, World Health Organization, 2019, 54-55.
3) Singhi AD, Seethala RR, Nason K, et al : Undifferentiated carcinoma of the esophagus : a clinicopathological study of 16 cases. Hum Pathol 2015, 46 : 366-375
4) Choi YY, Kim GH, Park DY : An incidental subepithelial mass in the esophagus. Lymphoepithelioma-like carcinoma appearing as a subepithelial tumor in the esophagus. Gastroenterology 2014, 146 : e1-2
5) Terada T : Epstein-Barr virus associated lymphoepithelial carcinoma of the esophagus. Int J Clin Exp Med 2013, 6 : 219-226
6) Agaimy A, Daum O, Markl B et al : SWI/SNF Complex-deficient Undifferentiated/Rhabdoid Carcinomas of the Gastrointestinal Tract : A Series of 13 Cases Highlighting Mutually Exclusive Loss of SMARCA4 and SMARCA2 and Frequent Co-inactivation of SMARCB1 and SMARCA2. Am J Surg Pathol 2016, 40 : 544-553
7) Kilic AI, Mirza K, Mehrotra S et al : A BAFfling liver aspirate : Metastatic high grade SMARCA4 deficient undifferentiated gastroesophageal junction carcinoma masquerading as a hematolymphoid malignancy. Diagn Cytopathol 2019, 47 : 725-732
P.95 掲載の参考文献
1) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版, 金原出版, 2015
2) Miettinen M, Fletcher CDM, Kindblom LG et al : Mesenchymal tumours of the oesophagus. World Health Organization, International Agency for Research on Cancer : WHO Classification of Tumour of the Digestive System, 4th ed, International Agency for Research on Cancer, 2010, 35-36
3) Abrikossoff A : Uber Myome, ausgehend von der quergestneiften willkurlichen Muskulatur. Virchows Arch Pathol Anat 1926, 260 : 215-233
4) Rubesin S, Herlinger H, Sigal H : Granular cell tumors of the esophagus. Gastrointest Radiol 1985, 10 : 11-15
5) WHO Classification of Tumours Editorial Board (ed) : WHO Classification of Tumours of the Digestive System Tumours, 5th ed, World Health Organization, 2019
6) 竹林克士, 木ノ下義宏, 小澤毅士ほか : 多発肝転移を伴った悪性食道顆粒細胞腫の1例. 日消外会誌 2012, 45 : 23-29
7) Pareja F, Brandes AH, Basili T et al : Loss-of-function mutations in ATP6AP1 and ATP6AP2 in granular cell tumors. Nat Commun 2018, 9 : 3533
8) Antonescu CR, Scheithauer BW, Woodruff JM (ed) : Tumors of the peripheral nervous system, AFIP atlas of tumor pathologu series 4, pp460, Maryland, 2013
9) 高木靖寛 : 顆粒細胞腫. 胃と腸 2017, 52 : 551
10) Postlethwait RW, Musser AW : Changes in the esophagus in 1,000 autopsy specimens. J Thorac Cardiovasc Surg 1974, 68 : 953-956
11) Lee LS, Singhal S, Brinster CJ et al : Current management of esophageal leiomyoma. J Am Coll Surg 2004, 198 : 136-146
12) McKeeby JL, Li X, Zhuang Z, et al : Multiple leiomyomas of the esophagus, lung, and uterus in multiple endocrine neoplasia Type 1. Am J Pathol 2001, 159 : 1121-1127
13) Ray S, Saluja SS, Gupta R, et al : Esophageal leiomyomatosis-an unusual cause of pseudoachalasia. Can J Gastroenterol 2008, 22 : 187-189
14) Hilal L, Barada K, Mukherji D et al : Gastrointestinal (GI) leiomyosarcoma (LMS) case series and review of diagnosis, management, and prognosis. Med Oncol 2016, 33 : 20
15) Miettinen M, Sarlomo-Rikala M, Sobin LH et al : Esophageal stromal tumors : a clinicopathologic, immunohistochemical, and molecular genetic study of 17 cases and comparison with esophageal leiomyomas and leiomyosarcomas. Am J Surg Pathol 2000, 24 : 211-222
16) Stout AP : Bizarre smooth muscle tumors of the stomach. Cancer 1962, 15 : 400-409
17) van de Rijn M, Hendrickson MR, Rouse RV : CD34 expression by gastrointestinal tract stromal tumors. Hum Pathol 1994, 25 : 766-771
18) Hirota S, Isozaki K, Moriyama Y et al : Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998, 23 : 577-580
19) Miettinen M, Lasota J : Gastrointestinal stromal tumors, review on morphology, molecular pathology, prognosis, and differential diagnosis. Arch Pathol lab med 2006, 130 : 1466-1478
20) 加藤剛, 比島恒和, 門馬久美子 : 食道GIST. 消化器内視鏡 2014, 26 : 1592-1593
21) Abraham SC, Krasinskas AM, Hofstetter WL et al : "Seedling" mesenchymal tumors (gastrointestinal stromal tumors and leiomyomas) are common incidental tumors of the esophagogastric junction. Am J Surg Pathol 2007, 31 : 1629-1635
22) Espinosa I, Lee CH, Kim MK et al : A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors. Am J Surg Pathol 2008, 32 : 210-218
23) West RB, Corless CL, Chen X et al : The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status. Am J Pathol 2004, 165 : 107-113
24) 杉山聡, 小出直彦, 奥村征大ほか : 胸腔鏡下に核出した食道神経鞘腫の1例. 日臨外会誌 2012, 73 : 2245-2250
25) Lasota J, Wasag B, Dansonka-Mieszkowska A et al : Evaluation of NF2 and NF1 tumor suppressor genes in distinctive gastrointestinal nerve sheath tumors traditionally diagnosed as benign schwannomas : s study of 20 cases. Lab Invest 2003, 83 : 1361-1371
P.99 掲載の参考文献
1) Bishop KD, Olszewski AJ : Epidemiology and survival outcomes of ocular and mucosal melanomas : a population-based analysis. Int J Cancer 2014, 134 : 2961-2971
2) Makuuchi H, Takubo K, Yanagisawa A et al : S. Esophageal malignant melanoma : analysis of 134 cases collected by the Japan Esophageal Society. Esophagus 2015, 12 : 158-169
3) Arai T, Yanagisawa A, Kondo F et al : Clinicopathologic characteristics of esophageal primary malignant melanoma. Esophagus 2016, 13 : 17-24
4) Hashimoto T, Makino T, Yamasaki M et al : Clinicopathological characteristics and survival of primary malignant melanoma of the esophagus. Oncol lett 2019, 18 : 1872-1880
5) Urabe M, Haruta S, Ohkura Y et al : Clinicopathological presentations and surgical outcomes of esophageal melanoma. Asian Cardiovasc Thorac Ann 2019, 27 : 548-553
6) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版, 金原出版, 2015
7) Nonaka D, Chiriboga L, Rubin BP : Sox 10 : a pan-schwannian and melanocytic marker. Am J Surg Pathol 2008, 32 : 1291-1298
8) Miettinen M, McCue PA, Sarlomo-Rikala M et al : Sox10-a marker for not only schwannian and melanocytic neoplasms but also myoepithelial cell tumors of soft tissue : a systematic analysis of 5134 tumors. Am J Surg Pathol 2015, 39 : 826-835
9) Dumaz N, Jouenne F, Delyon J et al : Atypical BRAF and NRAS Mutations in Mucosal Melanoma. Cancers (Basel) 2019, 11 : 1133
10) Delyon J, Chevret S, Jouary T et al : STAT3 Mediates Nilotinib Response in KIT-Altered Melanoma : A Phase II Multicenter Trial of the French Skin Cancer Network. J Invest Dermatol 2018, 138 : 58-67
P.104 掲載の参考文献
1) Odze RD, Montgomery EA, Wang HH, et al : Tumors of the Esophagus and Stomach. AFIP Atlas of Tumor Pathology, Series 4, 2019
2) Boni A, Lisovsky M, Dal Cin P, et al : Atypical lipomatous tumor mimicking giant fibrovascular polyp of the esophagus : report of a case and a critical review of literature. Hum Pathol 2013, 44 : 1165-1170
3) Graham RP, Yasir S, Fritchie KJ, et al : Polypoid fibroadipose tumors of the esophagus : 'giant fibrovascular polyp' or liposarcoma? A clinicopathological and molecular cytogenetic study of 13 cases. Mod Pathol 2018, 31 : 337-342
4) 新井冨生, 相田順子, 小宮山明他 : その他良性食道腫瘍ないし腫瘍様病変. 腫瘍病理鑑別診断アトラス 食道癌, 文光堂, 2012, 160-161
5) 竹内学, 薄田浩幸 : 食道良性腫瘍および腫瘍様病変の診断-脂肪腫. 2020, 胃と腸 55 : 274-277
6) WHO classification of Tumours Digestive System Tumours 5th ed, (WHO Classification of Tumours Editorial Board ed.) IARC press, Lyon, 2019
7) 蒲池紫乃, 岩下明徳, 吉田道夫他 : 食道の炎症性線維性ポリープ (inflammatory fibroid polyp) の1例. 胃と腸 2008, 43 : 327-332
8) Ricci R, Giustiniani MC, Gessi M, et al : Telocytes are the physiological counterpart of inflammatory fibroid polyps and PDGFRA-mutant GISTs. J Cell Mol Med 2018, 22 : 4856-4862
9) 新井俊文, 門馬久美子, 川田研郎他 : 食道に発生したpyogenic granulomaの1例. 胃と腸 2006, 41 : 983-989
P.108 掲載の参考文献
1) Mizobuchi S, Tachimori Y, Kato H et al : Metastatic esophageal tumors from distant primary lesions : report of three esophagectomies and study of 1835 autopsy cases. Jpn J Clin Oncol 1997, 27 : 410-414
2) Sanchez AA, Wu TT, Prieto VG et al : Comparison of primary and metastatic malignant melanoma of the esophagus : clinicopathologic review of 10 cases. Arch Pathol Lab Med 2008, 132 : 1623-1629
3) 川端良平, 木村豊, 川瀬朋乃ほか : 切除により長期生存が得られた乳癌食道転移の1例. 癌と化療 2014, 41 : 2024-2026
P.116 掲載の参考文献
1) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版, 金原出版, 2015
2) Sharma P, Dent J, Armstrong D et al : The development and validation of an endoscopic grading system for Barrett's esophagus : the Prague C & M criteria. Gastroenterology 2006, 131 : 1392-1399
3) Manabe N, Haruma K, Imamura H et al : Does short-segment columnar-lined esophagus elongate during a mean follow-up period of 5.7 years? Dig Endosc 2011, 23 : 166-172
4) Aida J, Vieth M, Shepherd NA et al : Is carcinoma in columnar-lined esophagus always located adjacent to intestinal metaplasia? : a Histopathologic assessment. Am J Surg Pathol 2015, 39 : 188-196
5) Theodorou D, Ayazi S, DeMeester SR et al : Intraluminal pH and goblet cell density in Barrett's esophagus. J Gastrointest Surg 2012, 16 : 469-474
6) Srivastava A, Golden KL, Sanchez CA et al : High Goblet Cell Count Is Inversely Associated with Ploidy Abnormalities and Risk of Adenocarcinoma in Barrett's Esophagus. PLoS One 2015, 10 : e0133403
7) Lavery DL, Martinez P, Gay LJ et al : Evolution of oesophageal adenocarcinoma from metaplastic columnar epithelium without goblet cells in Barrett's oesophagus. Gut 2016, 65 : 907-913
8) American Gastroenterological Association, Spechler SJ, Sharma P, et al : American Gastroenterological Association medical position statement on the management of Barrett's esophagus. Gastroenterology 2011, 140 : 1084-1091
9) 西隆之, 幕内博康, 小澤壯治ほか : Barrett腺癌の臨床病理学的検討-当科45例と本邦報告656例の検討-. 消内視鏡 2009, 21 : 1199-1206
10) Karimian M, Salamati M, Azami M : The relationship between metabolic syndrome and increased risk of Barrett's esophagus : an updated systematic review and meta-analysis. BMC Gastroenterol 2020, 20 : 138
11) Watanabe M, Tachimori Y, Oyama T, et al : Comprehensive registry of esophageal cancer in Japan, 2013. Esophagus 2021, 18 : 1-24
12) May A, Gossner L, Pech O et al : Intraepithelial high-grade neoplasia and early adenocarcinoma in short-segment Barrett's esophagus (SSBE) : curative treatment using local endoscopic treatment techniques. Endoscopy 2002, 34 : 604-610
13) Kuipers EJ, Spaander MC : Natural History of Barrett's Esophagus. Dig Dis Sci 2018, 63 : 1997-2004
14) Sato T, Kato Y, Matsuura M et al : Significance of palisading longitudinal esophagus vessels : identification of the true esophagogastric junction has histopathological and oncological considerations. Dig Dis Sci 2010, 55 : 3095-3101
15) Takubo K, Nixon JM, Jass JR : Ducts of esophageal glands proper and paneth cells in Barrett's esophagus : frequency in biopsy specimens. Pathology 1995, 27 : 315-317
16) Lorinc E, Oberg S : Hyperplasia of the submucosal glands of the columnar-lined oesophagus. Histopathology 2015, 66 : 726-731
17) Takubo K, Vieth M, Aryal G et al : Islands of squamous epithelium and their surrounding mucosa in columnar-lined esophagus : a pathognomonic feature of Barrett's esophagus? Hum Pathol 2005, 36 : 269-274
18) Aida J, Vieth M, Ell C et al : Palisade vessels as a new histologic marker of esophageal origin in ER specimens from columnar-lined esophagus. Am J Surg Pathol 2011, 35 : 1140-1145
19) 相田順子, 新井冨生, 石渡俊行 : 食道胃接合部領域の病理-炎症やBarrett化でどう変わる? -. 消内視鏡 2020, 32 : 690-696
20) Al Salihi S, Jaitly V, Saulino DM et al : Pancreatic Acinar Metaplasia in Distal Esophageal Biopsies Is Associated With Chronic Nonsteroidal Anti-inflammatory Drug Use. Arch Pathol Lab Med 2019, 143 : 510-512
21) Takubo K, Vieth M, Honma N et al : Ciliated surface in the esophagogastric junction zone : a precursor of Barrett's mucosa or ciliated pseudostratified metaplasia? Am J Surg Pathol 2005, 29 : 211-217
22) Glickman JN, Spechler SJ, Souza RF et al : Multilayered epithelium in mucosal biopsy specimens from the gastroesophageal junction region is a histologic marker of gastroesophageal reflux disease. Am J Surg Pathol 2009, 33 : 818-825
23) Board WCoTE : Tumours of the oesophagus. WHO Classification of Tumours Editorial Board (ed) : WHO Classification of Tumours, Digestive System Tumours, 5th ed, World Health Organization, 2019, 32-35
24) Reid BJ, Haggitt RC, Rubin CE et al : Observer variation in the diagnosis of dysplasia in Barrett's esophagus. Hum Pathol 1988, 19 : 166-178
25) Schlemper RJ, Riddell RH, Kato Y et al : The Vienna classification of gastrointestinal epithelial neoplasia. Gut 2000, 47 : 251-255
26) Naini BV, Souza RF, Odze RD : Barrett's Esophagus : A Comprehensive and Contemporary Review for Pathologists. Am J Surg Pathol 2016, 40 : e45-66
27) Shaheen NJ, Falk GW, Iyer PG et al : Corrigendum : ACG Clinical Guideline : Diagnosis and Management of Barrett's Esophagus. Am J Gastroenterol 2016, 111 : 1077
28) Montgomery EA, Oshima K, Voltaggio L (eds) : Pathology Survival Guides, Series 1 Survival Guide to Gastrointestinal Mucosal Biopsies, Innovative Science Press LLC, 2017
29) Michopoulos S : Critical appraisal of guidelines for screening and surveillance of Barrett's esophagus. Ann Transl Med 2018, 6 : 259
P.123 掲載の参考文献
1) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版, 金原出版, 2015
2) 日本胃癌学会 (編) : 臨床・病理 胃癌取扱い規約, 第15版, 金原出版, 2017
3) Kusano C, Gotoda T, Khor CJ et al : Changing trends in the proportion of adenocarcinoma of esophagogastric junction in a large tertiary referral center in Japan. J Gastroenterol Hepatol 2008, 23 : 1662-1665
4) Imamura Y, Watanabe M, Toihata T et al : Recent Incidence Trends of Surgically Resected Esophagogastric Junction Adenocarcinoma and Microsatellite Instability Status in Japanese Patients. Digestion 2019, 99 : 6-13
5) 西隆之, 幕内博康, 小澤壯治, ほか : Barrett腺癌の臨床病理学的検討-当科45例と本邦報告656例の検討-. 消内視鏡 2009, 21 : 1199-1206
6) Takubo K, Aida J, Naomoto Y et al : Cardiac rather than intestinal-type background in endoscopic resection specimens of minute Barrett adenocarcinoma. Hum Pathol 2009, 40 : 65-74
7) Zemler B, May A, Ell C et al : Early Barrett's carcinoma : the depth of infiltration of the tumour correlates with the degree of differentiation, the incidence of lymphatic vessel and venous invasion. Virchows Arch 2010, 456 : 609-614
8) Odze RD (ed) : Barrett dysplasia. WHO Classification of Tumours Editorial Board (ed) : WHO Classification of Tumours of the Digestive System Tumours, 5th ed, World Health Organization, 2019
9) Estrella JS, Hofstetter WL, Correa AM et al : Duplicated muscularis mucosae invasion has similar risk of lymph node metastasis and recurrence-free survival as intramucosal esophageal adenocarcinoma. Am J Surg Pathol 2011, 35 : 1045-1053
10) Ishihara R, Oyama T, Abe S et al : Risk of metastasis in adenocarcinoma of the esophagus : a multicenter retrospective study in a Japanese population. J Gastroenterol 2017, 52 : 800-808
11) Kaneshiro DK, Post JC Rybicki L, et al : Clinical significance of the duplicated muscularis mucosae in Barrett esophagus-related superficial adenocarcinoma. Am J Surg Pathol 2011, 35 : 697-700
12) Takubo K : Pathology of the Esophagas : An Atlas and Textbook, 3rd ed., Wiley, 2017
13) 田久保海誉, 新井富生, 桜井うららほか : 異所性胃粘膜島, 食道腺由来の腺癌. 田久保海誉, 大橋健一 (編) : 腫瘍病理鑑別診断アトラス 食道癌, 第1版, 文光堂, 2012
14) 熊谷義也 : 食道入口部異所性胃粘膜島 (inlet patch) の頻度に関する検討. Prog Dig Endosc 2005, 66 : 19-21
15) Takubo K, Tsuchiya S, Fukushi K et al : Dysplasia and reserve cell hyperplasia-like change in human esophagus. Acta Pathol Jpn 1981, 31 : 999-1013
16) Peitz U, Vieth M, Evert M et al : The prevalence of gastric heterotopia of the proximal esophagus is underestimated, but preneoplasia is rare-correlation with Barrett's esophagus. BMC Gastroetnetrol 2017, 17 : 87
17) Nomura K, Iizuka T, Inoshita N et al : Adenocarcinoma of the cervical esophagus arising from ectopic gastric mucosa : report of two cases and review of the literature. Clin J Gastroenterol 2015, 8 : 367-376
P.128 掲載の参考文献
1) Vakil N, van Zanten SV, Kahrilas P et al : The Montreal definition and classification of gastroesophageal reflux disease : a global evidence-based consensus. Am J Gastroenterol 2006, 101 : 1900-1920
2) Bleshman MH, Banner MP, Johnson RC et al : The inflammatory esophagogastric polyp and fold. Radiology 1978, 128 : 589-593
3) 笠原善郎, 浅田康行, 飯田善郎ほか : 組織学的に偽肉腫像を呈した食道胃接合部の隆起性病変 (pseudosarcomatous granulation) の1例. Gastroenterol Endosc 1994, 36 : 1992-1997
4) 立石陽子, 河内洋 : ≪Note≫ 食道胃接合部炎症性ポリープの病理. 消内視鏡 2020, 32 : 714-716
5) Isaacson P : Biopsy appearances easily mistaken for malignancy in gastrointestinal endoscopy. Histopathology 1982, 6 : 377-389
6) Dirschmid K, Walser J, Hugel H : Pseudomalignant erosion in hyperplastic gastric polyps. Cancer 1984, 54 : 2290-2293
7) 小沢俊文, 渡辺秀紀, 堀江裕子ほか : 食道胃接合部における炎症性ポリープの臨床病理学的検討. Gastroenterol Endosc 2002, 44 : 980-989
8) 高崎英己, 加島健司, 市川弘城ほか : 食道胃接合部に発生したpseudornalignant erosionの4例. 胃と腸 1993, 28 : 593-596
9) 辻野一三, 関 英幸, 北浜秀一ほか : Inflammatory esophagogastric polypの1例. Gastroenterol Endosc 1996, 38 : 2620-2624
10) 新井冨生, 相田順子, 田久保海誉 : 食道炎の病理診断-逆流性食道炎 (NERDを含む) -. 胃と腸 2011, 46 : 1146-1154
11) 相田順子, 新井冨生, 櫻井うららほか : 食道炎, 異型上皮, 扁平上皮癌の鑑別診断. 病理と臨床 2011, 29 : 926-931
12) 山田哲夫, 滝澤登一郎 : 形態学的立場からみた胃・食道逆流症の病理. 日内会誌 2000, 89 : 53-61
13) Fiocca R, Mastracci L, Riddell R et al : Development of consensus guidelines for the histologic recognition of microscopic esophagitis in patients with gastroesophageal reflux disease : the Esohisto project. Hum Pathol 2010, 41 : 223-231
14) Jessurun J, Yardley JH, Giardiello FM, et al : Intracytoplasmic plasma proteins in distended esophageal squamous cells (balloon cells). Mod Pathol 1988, 1 : 175-181
15) 木下芳一, 石原俊治, 石村典久ほか : 好酸球性食道炎の疫学と診断基準. 胃と腸 2018, 53 : 262-270
16) Dellon ES, Kim HP, Sperry SL et al : A phenotypic analysis shows that eosinophilic esophagitis is a progressive fibrostenotic disease. Gastrointest Endosc 2014, 79 : 577-585
17) Dellon ES, Speck O, Woodward K, et al : Distribution and variability of esophageal eosinophilia in patients undergoing upper endoscopy. Mod Pathol 2015, 28 : 383-390
18) Ismail-Beigi F, Pope CE 2nd : Distribution of the histological changes of gastroesophageal reflux in the distal esophagus of man. Gastroenterology 1974, 66 : 1109-1113
19) Kobayashi S, Kasugai T : Endoscopic and biopsy criteria for the diagnosis of esophagitis with a fiberoptic esophagoscope. Am J Dig Dis 1974, 19 : 345-352
20) Winter HS, Madara JL, Stafford RJ et al : Intraepithelial eosinophils : a new diagnostic criterion for reflux esophagitis. Gastroenterology 1982, 83 : 818-823
21) Solcia E, Villani L, Luinetti O et al : Altered intercellular glycoconjugates and dilated intercellular spaces of esophageal epithelium in reflux disease. Virchows Arch 2000, 436 : 207-216
22) Chatelain D, Flejou JF : [Hyperplastic polyp in heterotopic gastric mucosa : A rare lesion of the cervical esophagus]. Ann Pathol 1998, 18 : 415-417
23) Croyle P, Nikaidoh H, Currarino G : Inflammatory esophagogastric junction polyp. Am J Gastroenterol 1981, 76 : 438-440
24) Rabin MS, Bremner CG, Botha JR : The reflux gastroesophageal polyp. Am J Gastroenterol 1980, 73 : 451-452
25) Abraham SC, Singh VK, Yardley JH et al : Hyperplastic polyps of the esophagus and esophagogastric junction : histologic and clinicopathologic findings. Am J Surg Pathol 2001, 25 : 1180-1187
26) Eller JL, Ziter FM Jr, Zuck TF et al : Inflammatory polyp : a complication in esophagus lined by columnar epithelium. Radiology 1971, 98 : 145-146
27) Honda H, Kume K, Murakami H et al : Pseudomalignant erosion in hyperplastic polyp at esophago-gastric junction. J Gastroenterol Hepatol 2005, 20 : 800-801

第3部 鑑別ポイント

P.138 掲載の参考文献
1) 根本哲生 : 【食道】正常と炎症性疾患. 胃と腸 2014, 49 : 1906-1913
2) Nakayama H, Mitomi H, Imamhasan A et al : Stepwise overexpression of p63, p53, and cytokeratin 14 during progression of esophageal squamous intraepithelial neoplasia : useful immunohistochemical markers for differential diagnosis. Esophagus 9 : 1-8, 2012
3) 日本食道学会 (編) : 食道癌取扱い規約, 第11版, 金原出版, 2015
4) Kobayashi M, Kawachi H, Takizawa T et al : p53 Mutation analysis of low-grade dysplasia and high-grade dysplasia/carcinoma in situ of the esophagus using laser capture microdissection. Oncology 2006, 71 : 237-245
5) 立石陽子, 比島恒和 : 【食道】腫瘍性病変. 胃と腸 2013, 48 : 1508-1512
6) Dirschmid K, Walser J, Hugel H : Pseudomalignant erosion in hyperplastic gastric polyps. Cancer 1984, 54 : 2290-2293
7) Berry GJ, Pitts WC, Weiss LM : Pseudomalignant ulcerative change of the gastrointestinal tract. Hum Pathol 1991, 22 : 59-62
8) 藤原美奈子, 保利喜史, 古賀裕ほか : 好酸球性食道炎の病理診断. 胃と腸 2018, 53 : 271-278
P.140 掲載の参考文献
1) 日本食道学会 (編) : 食道癌診療ガイドライン 2017年版. 第4版. 金原出版, 2017
2) Noffsinger AE, Fenoglio-Preiser CM, Maru D, et al : Atlas of nontumor pathology, Gastrointestinal Diseases. American Registry of Pathology, Washington DC, 2007
3) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約. 第11版, 金原出版, 2015
4) Nishimura K, Tanaka Y, Tanaka S, et al : Reflux esophagitis and columnar-lined esophagus after cervical esophagectomy (following esophagectomy). Dis Esophagus 23 : 94-99, 2010
P.148 掲載の参考文献
1) 日本食道学会 (編) : 食道癌診療ガイドライン, 2017年版, 第4版, 金原出版, 2017
2) Tachimori Y, Ozawa S, Numasaki H et al : Comprehensive registry of esophageal cancer in Japan, 2012. Esophagus 2019, 16 : 221-245
3) UICC日本委員会TNM委員会 (訳) : TNM悪性腫瘍の分類, 第8版, 日本語版, 金原出版, 2017
4) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版, 金原出版, 2015
5) 根本哲生 : 病理からみた咽頭・食道表在癌の深達度診断. 胃と腸 2015, 50 : 507-514
6) 大倉康男 : 食道癌の初期浸潤像とは. 胃と腸 2012, 47 : 1334-1339
7) 依光展和, 小山恒男, 高橋亜紀子 : V-2深達度T1a-LPMの食道扁平上皮癌における浸潤形式別の検討. 第74回食道色素抄録集. 2015 : 13
8) 眞能正幸, 石黒信吾, 春日井務ほか : 食道癌の発育進展-脈管侵襲, リンパ節転移, 食道導管内進展を中心に-. 胃と腸 2000, 35 : 503-510
9) 藤田昌宏, 佐藤利宏, 細川正夫ほか : 治療成績からみた食道m3・sm癌の治療方針-外科手術例におけるリンパ節転移と病理像-. 胃と腸 2006, 41 : 1407-1415
10) 眞能正幸, 上堂文也, 石黒信吾ほか : 食道m3・sm1癌の臨床病理. 胃と腸 2002, 37 : 11-17
11) Egashira H, Yanagisawa A, Kato Y et al : Predictive factors for lymph node metastasis in esophageal squamous cell carcinoma containing or penetrating the muscularis mucosae : the utility of the droplet infiltration. Esophagus 2006, 3 : 47-52
12) Fuchinoue K, Nemoto T, Shimada H et al : Immunohistochemical analysis of tumor budding as predictor of lymph node metastasis from superficial esophageal squamous cell carcinoma. Esophagus 2020, 17 : 168-174
13) 大腸癌研究会 (編) : 大腸癌取扱い規約, 第9版, 金原出版, 2018
14) Takubo K, Sasajima K, Yamashita K et al : Double muscularis mucosa in Barrett's esophagus. Hum Pathol 1991, 22 : 1158-1161
15) Martinek JFP, Gregar J, Prochazka V et al : Standardy Ceske gastroenterologicke spolecnosti-endoskopicka lecba pacientu s Barrettovym jicnem a casnymi neoplaziemi jicnu. Gastroent Hepatol 2013, 67 : 479-487
16) Fitzgerald RC, di Pietro M, Ragunath K et al : British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagus. Gut 2014, 63 : 7-42
17) Aida J, Ishizaki T, Arai T et al : Prognostication of superficial Barrett's carcinoma : a Japanese multicenter study. Hum Pathol 2018, 76 : 156-166
P.156 掲載の参考文献
1) Perry C, Soomro I, Kaye P et al : Analysis of lymphatic and blood vessel invasion biomarkers in T1 esophagogastric adenocarcinomas for improved patient prognostication. Dis Esophagus 2015, 28 : 262-268
2) Tomita N, Matsumoto T, Hayashi T et al : Lymphatic invasion according to D2-40 immunostaining is a strong predictor of nodal metastasis in superficial squamous cell carcinoma of the esophagus : algorithm for risk of nodal metastasis based on lymphatic invasion. Pathol Int 2008, 58 : 282-287
3) Ishihara R, Oyama T, Abe S et al : Risk of metastasis in adenocarcinoma of the esophagus : a multicenter retrospective study in a Japanese population. J Gastroenterol 2017, 52 : 800-808
4) Zhang H, Chen X, Wang S et al : Poorer prognosis associated with simultaneous lymphatic and vascular invasion in patients with squamous carcinoma of the thoracic oesophagus. Eur J Cardiothorac Surg 2017, 52 : 378-384
5) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版, 金原出版, 2015
6) 日本食道学会 (編) : 食道癌診療ガイドライン 2017年版, 第4版, 金原出版, 2017, 86
7) 田久保海誉, 大橋健一 : 腫瘍病理鑑別診断アトラス 食道癌, 文光堂, 2012, 95-102
8) Tong L, Yuan S, Feng F, et al : Role of podoplanin expression in esophageal squamous cell carcinoma : a retrospective study. Dis Esophagus 2012, 25 : 72-80
9) Marsee DK, Pinkus GS, Hornick JL : Podoplanin (D2-40) is a highly effective marker of follicular dendritic cells. Appl Immunohistochem Mol Morphol 2009, 17 : 102-107
10) 河内洋, 根木真理子, 菅原江美子 : 浸潤度・脈管侵襲評価のための免疫染色. 病理と臨床 臨時増刊号 2020, 38 : 378-383
11) Brucher BL, Stein HJ, Werner M et al : Lymphatic vessel invasion is an independent prognostic factor in patients with a primary resected tumor with esophageal squamous cell carcinoma. Cancer 2001, 15 : 2228-2233
12) Imamura Y, Watanabe M, Nagai Y et al : Lymphatic vessel invasion detected by the D2-40 monoclonal antibody is an independent prognostic factor in node-negative esophageal squamous cell carcinoma. J Surg Oncol 2012, 105 : 277-283
13) Bai B, Ma W, Wang K et al : Detection of D2-40 monoclonal antibody-labeled lymphatic vessel invasion in esophageal squamous cell carcinoma and its clinicopathologic significance. Cancer Biol Med 2013, 10 : 81-85
14) 河内洋, 小林真季 : 食道扁平上皮癌ESD症例の病理学的リンパ節転移リスク評価. 消内視鏡 2018, 30 : 232-239
15) 林大久生, 三富弘之, 松岡隆ほか : 脈管 (リンパ管, 静脈) 侵襲について. 病理と臨床 2010, 28 : 626-634
P.161 掲載の参考文献
1) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版, 金原出版, 2015
2) Yamamoto E, Miyakawa A, Kohama G : Mode of invasion and lymph node metastasis in squamous cell carcinoma of the oral cavity. Head Neck Surg 1984, 6 : 938-947
3) 大腸癌研究会 (編) : 大腸癌取扱い規約, 第9版, 金原出版, 2018
4) 大腸癌研究会 (編) : 大腸癌治療ガイドライン 医師用, 2019年版, 金原出版, 2019
5) 冨松久信, 柳沢昭夫 : 早期食道癌-病型分類と深達度から早期食道癌の病理 表在癌とリンパ節転移との関係-. 臨消内科 1997, 12 : 1687-1693
6) 冨松久信, 加藤洋, 柳澤昭夫 : n (+) 食道sm癌・n (-) 食道sm癌の病理学的比較. 消内視鏡 1999, 11 : 1355-1361
8) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第10版 補訂版, 金原出版, 2008
9) 小山恒男, 宮田佳典, 島谷茂樹ほか : 第46回食道色素研究会アンケート調査報告 転移のあったm3・sm1食道癌の特徴. 胃と腸 2002, 37 : 71-74
10) 日本口腔腫瘍学会 (編) : 口腔癌取扱い規約, 第2版, 金原出版, 2019
11) Kaihara T, Kusaka T, Kawamata H et al : Decreased expression of E-cadherin and Yamamoto-Kohama's mode of invasion highly correlates with lymph node metastasis in esophageal squamous cell carcinoma. Pathobiology 2001, 69 : 172-178
12) 尾田典隆, 小野祐子 : 食道扁平上皮癌の累積生存率と浸潤様式に関する病理学的検討-インボルクリン発現との関連について-. 日消誌 2004, 101 : 591-597
13) 知花洋子, 甲斐原司, 市川一仁ほか : リンパ節転移を伴った食道m3・sm1癌の病理学的特徴-Yamamoto-Kohamaの分類とE-cadherinの発現様式の意義-. 消化器内視鏡 2003, 15 : 379-387
14) 河内洋, 江石義信, 小池盛雄 : 大腸SM癌の病理診断とその問題点-簇出tumor budding/sprouting-. 胃と腸 2009, 44 : 1249-1254
15) 大腸癌研究会 (編) : 大腸癌取扱い規約, 第8版, 金原出版, 2013
16) 今井環 : 人体癌発育状況の形態学的考察. 福岡医誌 1954, 45 : 72-102
17) Morodomi T, Isomoto H, Shirouzu K et al : An index for estimating the probability of lymph node metastasis in rectal cancers. Cancer 1989, 63 : 539-543
18) 河内洋 : 浸潤様式の評価, 臨床的意義について. 病理と臨床 2010, 28 : 642-647
19) 藤田昌宏, 安部達也, 細川正夫ほか : 食道粘膜下層癌の病態-病理学の立場から-. 胃と腸 2002, 37 : 1263-1272
20) 八尾隆史, 野村亮介, 梶山美明 : 悪性度の高い食道表在癌-臨床病理学的特徴-. 胃と腸 2013, 48 : 1245-1252
21) Roh MS, Lee JI, Choi PJ : Tumor budding as a useful prognostic maker in esophageal squamous cell carcinoma. Dis Esophagus 2004, 17 : 333-337
22) Koike M, Kodera Y, Itoh Y et al : Multivariate analysis of the pathologic features of esophageal squamous cell cancer : tumor budding is a significant independent prognostic factor. Ann Surg Oncol 2008, 15 : 1977-1982
23) 日本食道学会 (編) : 食道癌診療ガイドライン 2017年版, 第4版, 金原出版, 2017

第4部 臨床との連携

P.171 掲載の参考文献
1) 丹羽寛文 : 日本消化器内視鏡学会50年の歩み. Gastroenterol Endosc 2008, 50 : 3409-3415
2) 吉田操, 門馬久美子, 出江洋介 : 食道癌診療の歴史と展望. 日本臨牀 2011, 69 : 9-16
3) 平澤大, 前田有紀, 長南明道ほか : 通常内視鏡の画像の成り立ち-食道-. 胃と腸 2018, 53 : 1244-1251
4) Muto M, Minashi K, Yano T et al : Early detection of superficial squamous cell carcinoma in the head and neck region and esophagus by narrow band imaging : a multicenter randomized controlled trial. J Clin Oncol 2010, 28 : 1566-1572
5) 大森泰 : 危険なヨード不染帯所見Pink Color signの検討. Gastroenterological Endoscopy 2001, 43 (suppl 2) : 1613
6) Kouzu T, Hishikawa E, Miyazaki S : What are the findings of esophageal cancer to be treated endoscopically? Abdom Inaging 2003, 28 : 470-476
7) 平澤大 : 畳目模様 (Tatamime sign). 胃と腸 2012, 47 : 677
8) 平澤大, 藤田直孝, 前田有紀ほか : 肉眼形態と血管形態からみた発育伸展-主に0-IIcに関する発育伸展-. 胃と腸 2012, 47 : 1383-1392
9) Oyama T, Inoue H, Arima M et al : Prediction of invasion depth of superficial squamous cell carcinoma based on microvessel morphology : magnifying endoscopic classification of the Japan Esophageal Society. Esophagus 2017, 14 : 105-112
10) 有馬美和子, 多田正弘, 有馬秀明ほか : 超音波内視鏡による食道m3・sm癌の深達度・リンパ節転移・再発診断の精度. 胃と腸 2006, 41 : 1386-1396
11) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第10版 補訂版, 金原出版, 2008
P.176 掲載の参考文献
1) Oyama T, Inoue H, Arima M et al : Prediction of the invasion depth of superficial squamous cell carcinoma based on microvessel morphology : magnifying endoscopic classification of the Japan Esophageal Society. Esophagus 2017, 14 : 105-112
2) 熊谷洋一, 天野邦彦, 鈴木興秀ほか : SECNの意義. 胃と腸 2018, 53 : 1335-1341
3) Minami H, Inoue H, Ikeda H et al : Usefulness of Background Coloration in Detection of Esophago-Pharyngeal Lesions Using NBI Magnification. Gastroenterol Res Pract 2012, 2012 : 529782
4) Kumagai Y, Inoue H, Nagai K et al : Magnifying endoscopy, stereoscopic microscopy and the microvascular architecture superficial esophageal carcinoma. Endoscopy 2002, 34 : 369-375
5) 川田研郎, 門馬久美子, 河内洋ほか : contact endoscopyが拓く食道ヨード不染帯の鑑別. 胃と腸 2006, 41 : 225-232
6) Kumagai Y, Kawada K, Yamazaki S et al : Endocytoscopic observation for esophageal squamous cell carcinoma : can biopsy histology be omitted? Dis Esophagus 2009, 22 : 505-512
7) 熊谷洋一, 川田研郎, 田久保海誉ほか : 超拡大内視鏡 (Endocytoscopy system) による食道病変の診断. Gastroenterol Endosc 2017, 59 : 207-218
8) 熊谷洋一, 川田研郎, 田久保海誉ほか : 食道領域のendocytoscopyの最新知見. 胃と腸 2019, 54 : 374-383
9) 熊谷洋一, 川田研郎, 田久保海誉 : 光学式超拡大内視鏡 (エンドサイトスコープ) による上部消化管表在癌診断. Gastroenterol Endosc 2019, 61 : 1513-1522
10) Kumagai Y, Takubo K, Kawada K et al. Diagnosis using deep-learning artificial intelligence based on the endocytoscopic observation of the esophagus. Esophagus. 2019 ; 16 : 180-187.
P.181 掲載の参考文献
1) 日本食道学会 (編) : 食道癌診療ガイドライン 2017年版, 第4版, 金原出版, 2017
2) Kitagawa Y, Uno T, Oyama T et al : Esophageal cancer practice guidelines 2017 edited by the Japan Esophageal Society : part 1. Esophagus 2019, 16 : 1-24
3) Kitagawa Y, Uno T, Oyama T et al : Esophageal cancer practice guidelines 2017 edited by the Japan esophageal society : part 2. Esophagus 2019, 16 : 25-43
4) 坊岡英祐, 北川雄光 : 「食道癌診療ガイドライン」2017年版改訂の要点. 日本臨牀, 2018, 76 : 127-132
P.188 掲載の参考文献
1) Tachimori Y, Ozawa S, Numasaki H et al : Comprehensive registry of esophageal cancer in Japan, 2012. Esophagus 2019, 16 : 221-245
2) 小山恒男, 宮田佳典, 島谷茂樹ほか : 第46回食道色素研究会アンケート調査報告-転移のあったm3・sm1食道癌の特徴-. 胃と腸 2002, 37 : 71-74
3) Minashi K, Nihei K, Mizusawa J et al : Efficacy of Endoscopic Resection and Selective Chemoradiotherapy for Stage I Esophageal Squamous Cell Carcinoma. Gastroenterology 2019, 157 : 382-390
4) 日本食道学会 (編) : 食道癌診療ガイドライン 2017年版, 第4版, 金原出版, 2017, 16
5) Oyama T, Tomori A, Hotta K et al : Endoscopic submucosal dissection of early esophageal cancer. Clin Gastroenterol Hepatol 2005, 3 : S67-70
6) Yano T, Kasai H, Horimatsu T et al : A multicenter phase II study of salvage photodynamic therapy using talaporfin sodium (ME2906) and a diode laser (PNL6405EPG) for local failure after chemoradiotherapy or radiotherapy for esophageal cancer. Oncotarget 2017, 8 : 22135-22144.
7) 鶴丸昌彦 : 胸部食道癌に対するリンパ節郭清. 日消外会誌 1998, 31 ; 128-132
8) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版, 金原出版, 2015
9) Osugi H, Takemura M, Higashino M et al : Video-assisted thoracoscopic esophagectomy and radical lymph node dissection for esophageal cancer. A series of 75 cases. Surg Endosc 2002, 16 : 1588-1593
10) Palanivelu C, Prakash A, Senthilkumar R et al : Minimally invasive esophagectomy : thoracoscopic mobilization of the esophagus and mediastinal lymphadenectomy in prone position-experience 130 patients. J Am Coll Surg 2006, 203 : 7-16
11) 河野辰幸, 三宅智 (編) : 胃による食道再建術. 食道癌診療マニュアル, 診断と治療社, 2012
12) 遠藤光夫 (編) : 胸部食道癌の標準手術. 食道癌の外科治療マニュアル, へるす出版, 2000, 67-80
13) Sasako M, Sano T, Yamamoto S et al : Left thoracoabdominal approach versus abdominal-transhiatal approach for gastric cancer of the cardia or subcardia : a randomised controlled trial. Lancet Oncol 2006, 7 : 644-651
14) Nakajima Y, Kawada K, Tokairin Y et al : 'Larynx-preserving surgery' for cervical esophageal carcinoma can preserve the vocal function and improve the clinical outcome. Esophagus 2017, 14 : 76-83
P.193 掲載の参考文献
1) 日本食道学会 (編) : 食道癌診療ガイドライン 2017年版, 第4版, 金原出版, 2017
2) Kato K, Igaki H, Ito Y et al : Parallel-group controlled trial of esophagectomy versus chemoradiotherapy in patients with clinical stage I esophageal carcinoma (JCOG0502). J Clin Oncol 2019, 37 : (suppl 4 ; abstr 7)
3) Ando N, Kato H, Igaki H et al : A randomized trial comparing postoperative adjuvant chemotherapy with cisplatin and 5-fluorouracil versus preoperative chemotherapy for localized advanced squamous cell carcinoma of the thoracic esophagus (JCOG9907). Ann Surg Oncol 2012, 19 : 68-74
4) Ito Y, Takeuchi H, Ogawa G et al : A single-arm confirmatory study of definitive chemoradiotherapy (dCRT) including salvage treatment in patients (pts) with clinical (c) stage II/III esophageal carcinoma (EC) (JCOG0909). J Clin Oncol 2018, 36 : (suppl ; abstr 4051)
5) Hara H, Tahara M, Daiko M et al : Phase II feasibility study of preoperative chemotherapy with docetaxel, cisplatin, and fluorouracil for esophageal squamous cell carcinoma. Cancer Sci 2013, 104 : 1455-1460
6) Shinoda M, Ando M, Kato K et al : Randomized study of low-dose versus standard-dose chemoradiotherapy for unresectable esophageal squamous cell carcinoma (JCOG0303). Cancer Sci 2015, 106 : 407-412
7) Ohtsu A, Boku N, Muro K et al : Definitive chemoradiotherapy for T4 and/or M1 lymph node squamous cell carcinoma of the esophagus. J Clin Oncol 1999, 17 : 2915-2921
8) Iizuka T, Kakegawa T, Ide H et al : Phase II evaluation of cisplatin and 5-fluorouracil in advanced squamous cell carcinoma of the esophagus : a Japanese Esophageal Oncology Group Trial. Jpn J Clin Oncol 1992, 22 : 172-176
9) Hironaka S, Tsubosa Y, Mizusawa J et al : Phase I/II trial of 2-weekly docetaxel combined with cisplatin plus fluorouracil in metastatic esophageal cancer (JCOG0807). Cancer Sci 2014, 105 : 1189-1195
10) 日本食道学会, 日本臨床腫瘍学会, 日本癌治療学会 : 食道癌に対するオキサリプラチンの使用について. https://www.esophagus.jp/private/information/news_20191213.html
11) Kato K, Cho BC, Takahashi M et al : Nivolumab versus chemotherapy in patients with advanced oesophageal squamous cell carcinoma refractory or intolerant to previous chemotherapy (ATTRACTION-3) : a multicentre, randomised, open-label, phase 3 trial. Lancet Oncol 2019, 20 : 1506-1517
12) Kojima T, Shah MA, Muro K et al : Randomized Phase III KEYNOTE-181 Study of Pembrolizumab Versus Chemotherapy in Advanced Esophageal Cancer. J Clin Oncol 2020, 38 : 4138-4148
13) 厚生労働省 : 最適使用推進ガイドライン ペムブロリズマブ (遺伝子組換え) ~食道癌. (令和2年8月21日) pmda.go.jp/files/000236151.pdf
14) Muro K, Hamaguchi T, Ohtsu A et al : A phase II study of single-agent docetaxel in patients with metastatic esophageal cancer. Ann Oncol 2004, 15 : 955-959
15) Kato K, Tahara M, Hironaka S et al : A phase II study of paclitaxel by weekly 1-h infusion for advanced or recurrent esophageal cancer in patients who had previously received platinum-based chemotherapy. Cancer Chemother Pharmacol 2011, 67 : 1265-1272
17) Yamaguchi T, Machida N, Morizane C et al : Multicenter retrospective analysis of systemic chemotherapy for advanced neuroendocrine carcinoma of the digestive system. Cancer Sci 2014, 105 : 1176-1181
18) Chin K, Baba S, Hosaka H et al : Irinotecan plus cisplatin for therapy of small-cell carcinoma of the esophagus : report of 12 cases from single institution experience. Jpn J Clin Oncol 2008, 38 : 426-431
19) Kitagawa Y, Osumi H, Shinozaki E et al : Safety and efficacy of amrubicin monotherapy in patients with platinum-refractory metastatic neuroendocrine carcinoma of the gastrointestinal tract : a single cancer center retrospective study. Cancer Manag Res 2019, 11 : 5757-5764
20) D'Angelo SP, Larkin J, Sosman JA et al : Efficacy and Safety of Nivolumab Alone or in Combination With Ipilimumab in Patients With Mucosal Melanoma : A Pooled Analysis. J Clin Oncol 2017, 35 : 226-235
21) Hamid O, Robert C, Ribas A et al : Antitumour activity of pembrolizumab in advanced mucosal melanoma : a posthoc analysis of KEYNOTE-001, 002, 006. Br J Cancer 2018, 119 : 670-674
P.200 掲載の参考文献
1) 日本病理学会 (編) : ゲノム研究用・診療用病理組織検体取扱い規程, 羊土社, 2019, 130-132
2) 九嶋亮治 : 食道・胃. 深山正久, 小田義直, 坂元亨宇ほか (編) : 組織病理アトラス, 第6版, 文光堂, 2015, 90-91
3) 日本食道学会 (編) : 食道癌取扱い規約, 第11版, 金原出版, 2015, 27-28
4) Takubo K, Fujii S : Oesophageal squamous dysplasia. WHO Classification of Tumours Editorial Board (ed) : WHO Classification of Tumours of the Digestive System Tumours, 5th Edition, World Health Organization, 2019, 36-37
P.205 掲載の参考文献
1) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版, 金原出版, 2015
2) WHO Classification of Tumours Editorial Board (ed) : WHO Classification of Tumours of the Digestive System Tumours, 5th ed, World Health Organization, 2019
3) Egashira H, Yanagisawa A, Kato Y : Predictive factors for lymph node metastasis in esophageal squamous cell carcinomas contacting or penetrating the muscularis mucosae : the utility of droplet infiltration. Esophagus 2006, 3 : 47-52
4) Fuchinoue K, Nemoto T, Shimada H et al : Immunohistochemical analysis of tumor budding as predictor of lymph node metastasis from superficial esophageal squamous cell carcinoma. Esophagus 2020, 17 : 168-174
5) 日本食道学会 (編) : 食道癌診療ガイドライン 2017年版, 第4版, 金原出版, 2017 : 42-44
P.209 掲載の参考文献
1) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第11版, 金原出版, 2015
2) James DB, Mary KG, Christian W : TNM Classification of Malignant Tumours, 8th ed, Wiley Backwell, 2017
3) 日本食道学会 (編) : 臨床・病理 食道癌取扱い規約, 第10版, 金原出版, 2007
4) Takubo K, Fujii S : Oesophageal squamous dysplasia. WHO Classification of Tumours Editorial Board (ed) : WHO Classification of Tumours Digestive System Tumours, 5th ed, World Health Organization, 2019, 36-37
P.217 掲載の参考文献
1) 大星章一, 下里幸雄, 板倉克明ほか : 癌放射線療法の病理〔1〕癌組織の治癒過程の組織学的追跡 (その1) (その2). 医学のあゆみ 1967, 61 : 618-625, 665-671
2) Japanese Gastric Cancer Association : Japanese classification of gastric carcinoma : 3rd English edition. Gastric cancer 2011, 14 : 101-112
3) 日本食道学会 (編) : 食道癌取扱い規約, 第11版, 金原出版, 2015, 30-31, 92-94
4) Thies S, Langer R : Tumor regression grading of gastrointestinal carcinomas after neoadjuvant treatment. Front Oncol 2013, 3 : 262
5) Langer R, Becker K : Tumor regression grading of gastrointestinal cancers after neoadjuvant therapy. Virchows Arch 2018, 472 : 175-186
6) Klevebro F, Tsekrekos A, Low D et al : Relevant issues in tumor regression grading of histopathological response to neoadjuvant treatment in adenocarcinomas of the esophagus and gastroesophageal junction. Dis Esophagus 2020, 33 : dosa 005
7) 日本食道学会 (編) : 食道癌診療ガイドライン 2017年版, 第4版, 金原出版, 2017

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