成分栄養剤のこれまでとこれから　エビデンスからの期待

出版社： 先端医学社
著者：
発行日： 2023-01-31
分野： 臨床医学：一般  >  栄養/食事/輸血
ISBN： 9784865505832
電子書籍版： 2023-01-31 （第1版第1刷）
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商品紹介

わが国で開発・製品化され、発展を遂げた成分栄養剤（エレンタール®配合内用剤）は今や消化器疾患の治療において非常に重要な選択肢となっている。本書では成分栄養剤を用いた栄養管理・栄養療法について、周術期・IBD・がん治療の支持療法・膵疾患の4つの分野でこれまでに蓄積された豊富なエビデンスを詳細に解説している。臨床栄養に携わる医療スタッフにとって必読の一冊。

目次

  • PART 1　序章
    　わが国における成分栄養剤の開発の経緯と軌跡・今後の展望
    　
    PART 2　周術期における成分栄養剤のこれまでとこれから
    　1.周術期における成分栄養剤の位置づけと役割
    　2.侵襲時のアミノ酸代謝
    　3.術後回復促進プログラム（ERAS）における成分栄養剤の役割
    　4.膵頭十二指腸切除術の栄養管理と成分栄養療法
    　5.食道がん術後早期経腸栄養：成分栄養剤を用いた乳び胸発症予防
    　6.胃瘻栄養時の成分栄養剤の胃排出速度

    PART 3　IBDにおける成分栄養剤のこれまでとこれから
    　1.IBDにおける成分栄養剤の歴史と役割
    　2.IBDの治療における成分栄養剤の位置づけ
    　3.生物学的製剤時代における成分栄養療法の位置づけ
    　4.小児IBD治療における成分栄養療法
    　5.IBDの外科治療における成分栄養療法の役割
    　6.IBD治療における成分栄養療法のアドヒアランス向上の意義と実際（エビデンスの視点も交え）
    　7.IBDの病態と成分栄養剤の機能　IBDにおける栄養素と成分栄養剤の機能
    　　　～エネルギー，タンパク質，脂肪の影響～
    　8.IBDにおける腸内細菌叢のかかわりと成分栄養剤の役割

    Part 4 がん支持療法における成分栄養剤のこれまでとこれから
    　1.がん支持療法における成分栄養剤の位置づけと役割
    　2.胃がんの外科的治療における成分栄養剤の役割
    　　(1) 胃切除後の成分栄養剤による早期介入（KSES001・002試験）
    　　(2) 胃がん術後化学療法における成分栄養剤の併用療法（OGSG1108）
    　3.食道がんの化学療法における成分栄養剤の実際
    　4.口腔がん治療における成分栄養剤の実際

    Part 5 膵疾患における成分栄養剤のこれまでとこれから
    　1.膵疾患における成分栄養剤の位置づけと役割
    　2.成分栄養剤のコレシストキニン（CCK）分泌に及ぼす影響
    　3.膵炎における成分栄養剤の実際
    　4.膵がんにおける成分栄養剤の実際

この書籍の参考文献

参考文献のリンクは、リンク先の都合等により正しく表示されない場合がありますので、あらかじめご了承下さい。

本参考文献は電子書籍掲載内容を元にしております。

Part 1 序章

P.18 掲載の参考文献
1) 医薬品インタビューフォーム : 成分栄養剤エレンタール(R) 配合内用剤 (2016年4月改訂, 第5版)
 
2) 小越章平 : 国産ED-食品会社による初の薬品開発-. 静脈・経腸栄養の発展を思い出すままに, ジェフコーポレーション, 東京, 2011, pp.29-32
 
3) 小越章平 : 成分栄養研究会設立と保険薬として承認. 静脈・経腸栄養の発展を思い出すままに, ジェフコーポレーション, 東京, 2011, pp. 45-48
 
4) Greenstein JP, Birnbaum SM, Winitz M et al : Quantitative nutritional studies with water-soluble, chemically defined diets. I. Growth, reproduction and lactation in rats. Arch Biochem Biophys 72 : 396-416, 1957
PubMed
5) Winitz M, Seedam DA, Graff J : Studies in metabolic nutrition employing chemically defined diets. I. Extended feeding of normal human adult males. Am J Clin Nutr 23 : 525-545, 1970
 
6) Sugimura T, Birnbaum SM, Winitz M et al : Quantitative nutritional studies with water-soluble, chemically defined diets. VII. Nitrogen balance in normal and tumor-bearing rats following forced feeding. Arch Biochem Biophys 81 : 439-447, 1959
PubMed
7) 小越章平, 佐藤博 : EDの特性と適応. 臨床外科 34 : 457-462, 1979
 
8) Dudrick SJ, Wilmore DW, Vars HM et al : Long-term total parenteral nutrition with growth, development, and positive nitrogen balance. Surgery 64 : 134-142, 1968
PubMed
9) Bury KD, Stephens RV, Randall HT : Use of a chemically defined, liquid, elemental diet for nutritional management of fistulas of the alimentary tract. Am J Surg 121 : 174-183, 1971
PubMed
10) Kaminski MV J : Enteral hyperalimentation. Surg Gynecol Obstet 143 : 12-16, 1976
 
11) 中山博, 小沢弘侑, 鈴木昭一 : 消化管瘻などに対するElemental dietの効果. 成分栄養研究会会誌 1 : 31-36, 1977
 
12) 小越章平 : 日本人向けEDの開発. 静脈・経腸栄養の発展を思い出すままに, ジェフコーポレーション, 東京, 2011, pp. 37-40
 
13) 鍋谷圭宏 : いま改めて考える「がん診療における経腸栄養」-begin. continue-. アミノ酸研究 9 : 65-70, 2015
 
14) 永井鑑. 五関謹秀, 井上晴洋ほか : 汚染経腸栄養剤に起因すると推測されたE. cloacae敗血症の2例. 外科と代謝・栄養 31 : 315-320, 1997
Medical*Online
15) 樋渡信夫, 今野保敏, 小林和人ほか : 経腸栄養法の実際-炎症性腸疾患-. 臨床外科 40 : 73-80, 1985
 
16) Takagi S, Utsunomiya K, Kuriyama S et al : Effectiveness of an 'half elemental diet' as maintenance therapy for Crohn's disease : A randomized-controlled trial. Aliment Pharmacol Ther 24 : 1333-1340, 2006
PubMed
17) 日本在宅静脈経腸栄養研究会 : 研究会概要. http://www.pedsurg.med.osaka-u.ac.jp/jsghpen/outline.html
 
18) 慢性膵炎診療ガイドライン 2021 改訂第3版, 日本消化器病学会編, 南江堂, 東京, 2021, pp.71-72
 
19) Tanaka Y, Takahashi T, Yamaguchi K et al : Elemental diet plus glutamine for the prevention of mucositis in esophageal cancer patients receiving chemotherapy : a feasibility study. Support Care Cancer 24 : 933-941, 2016
PubMed
20) 第10回日本消化器外科学会総会パネルディスカッション. 日本消化器外科学会雑誌 11 : 53, 1978
 

Part 2 周術期における成分栄養剤のこれまでとこれから

P.25 掲載の参考文献
1) 小越章平 : 成分栄養研究会設立と保険薬として承認. 静脈・経腸栄養の発展を思い出すままに, ジェフコーポレーション, 東京, 2011, pp. 45-48
 
2) 小越章平, 佐藤博 : EDの特性と適応. 臨床外科 34 : 457-462, 1979
 
3) 鍋谷圭宏, 大村健二 : combined nutritional therapy. 外科と代謝・栄養 52 : 191-194, 2018
 
4) 相場哲朗, 小山真, 福田稔ほか : Elemental Dietによる大腸手術の前処置. 臨床外科 35 : 1734-1740, 1980
 
5) 堀部大輔. 丸山尚嗣, 鍋谷圭宏ほか : 狭窄の強い大腸癌患者に対する成分栄養剤経口投与による術前栄養管理. 臨床外科 64 : 1577-1581, 2009
 
6) Yoshida T, Homma S, Ichikawa N et al : Preoperative elemental diet before laparoscopic anterior resection in patients with advanced stenotic rectal cancer. J Anus Rectum Colon 5 : 395-404, 2021
PubMed
7) 小山真, 相場哲朗, 山岸良男ほか : ED投与方法の実際. 臨床外科 34 : 463-469, 1979
 
8) Ishibe A, Ota M, Kanazawa A et al : Nutritional management of anastomotic leakage after colorectal cancer surgery using elemental diet jelly. Hepato gastroenterology 62 : 30-33, 2015
PubMed
9) 鍋谷圭宏,. 大竹慶尭, 前田恵理ほか : [症例から考える栄養製剤の使い方] 食道がん (周術期を中心に). 月刊薬事 63 : 1569-1574, 2021
Medical*Online
10) Takesue T, Takeuchi H, Ogura M et al : A prospective randomized trial of enteral nutrition after thoracoscopic esophagectomy for esophageal cancer. Ann Surg Oncol 22 (Suppl 3) : S802-S809, 2015
 
11) 星智和, 和久勝昭, 長谷川公治ほか : 胃癌治療上の栄養管理 : 術後早期経腸栄養. 日本臨牀 72 (増刊号 1) : 565-569, 2014
 
12) 岸本浩史, 笹原孝太郎, 小田切範晃ほか : 高リスク胃全摘症例における術後早期経腸栄養の効果. 日本外科系連合学会誌 40 : 211-216, 2015
 
13) Aoyama T, Sato T, Maezawa Y et al : Postoperative weight loss leads to poor survival through poor S-1 efficacy in patients with stage II/III gastric cancer. Int J Clin Oncol 22 : 476-483, 2017
 
14) Imamura H, Nishikawa K, Kishi K et al : Effects of an oral elemental nutritional supplement on post-gastrectomy body weight loss in gastric cancer patients : a randomized controlled clinical trial. Ann Surg Oncol 23 : 2928-2935, 2016
PubMed
15) Kimura Y, Nishikawa K, Kishi K et al : Long-term effects of an oral elemental nutritional supplement on post-gastrectomy body weight loss in gastric cancer patients (KSES002). Ann Gastroenterol Surg 3 : 648-656, 2019
PubMed
16) Shichinohe T, Sasaki T, Kitashiro S et al : Impact of elemental diet on early recovery after laparoscopic colectomy : findings of a randomized controlled trial. Surg Today 47 : 166-173, 2017
PubMed
17) 坂本昭雄 : Elemental dietの十二指腸内注入時における膵外分泌におよぼす影響. 日本消化器外科学会雑誌 12 : 139-149, 1979
 
18) 山室美砂子 : Elemental Dietの膵液胆汁分泌に及ぼす影響に関する基礎的検討. 日本消化器病学会雑誌 79 : 1137-1146, 1982
 
19) 成人の病態別栄養管理 : 周術期 術後消化管縫合不全に対する保存的治療時の栄養管理は? 日本静脈経腸栄養学会編, 静脈経腸栄養ガイドライン (第3版), 照林社. 東京, 2013, pp. 228-234
 
20) Mori R, Matsuyama R, Taniguchi K, et al : Efficacy of prolonged elemental diet therapy after pancreaticoduodenectomy for pancreatic ductal adenocarcinoma : A pilot prospective randomized trial (UMIN000004108). Clin Nutr ESPEN 34 : 116-124, 2019
PubMed
21) 第10回日本消化器外科学会総会パネルディスカッション. 日本消化器外科学会雑誌 11 : 53, 1978
 
P.30 掲載の参考文献
1) Gillis C, Carli F : Promoting perioperative metabolic and nutritional care. Anesthesiology 123 : 1455-1472, 2015
PubMed
2) Rittler P, Jacobs R, Demmelmair H et al : Dynamics of albumin synthesis after major rectal operation. Surgery 141 : 660-666, 2007
PubMed
3) Caso G, Vosswinkel JA, Garlick PJ et al : Altered protein metabolism following coronary artery bypass graft (CABG) surgery. Clin Sci (Lond) 114 : 339-346, 2008
PubMed
4) Soeters PB, van de Poll MCG, van Gemert WG et al : Amino acid adequacy in pathophysiological states. J Nutr 134 (6 Suppl) : 1575S-1582S, 2004
 
5) Chapple LS, van Gassel RJJ, Rooyackers O : Protein metabolism in critical illness. Curr Opin Crit Care 28 : 367-373, 2022
PubMed
6) 深柄和彦, 福島亮治 : WEBアンケート調査から見る外科医のアルブミンに対する認識と術後の栄養管理の現状. 外科と代謝・栄養 55 : 141-150, 2021
Medical*Online
7) Weijzen MEG, van Gassel RJJ, Kouw IWK et al : Ingestion of free amino acids compared with an equivalent amount of intact protein results in more rapid amino acid absorption and greater postprandial plasma amino acid availability without affecting muscle protein synthesis rates in young adults in a double-blind randomized trial. J Nutr 152 : 59-67, 2022
 
8) Sundstrom Rehal M, Liebau F, Wernerman J et al : Whole-body protein kinetics in critically ill patients during 50 or 100% energy provision by enteral nutrition : A randomized cross-over study. PLos One 15 : e0240045, 2020
PubMed
9) Sundstrom Rehal M, Liebau F, Tjader I et al : A supplemental intravenous amino acid infusion sustains a positive protein balance for 24 hours in critically ill patients. Crit Care 21 : 298, 2017
PubMed
P.36 掲載の参考文献
1) Gustafsson UO, Scott MJ, Schwenk W et al : Guidelines for perioperative care in elective colonic surgery : Enhanced Recovery After Surgery (ERAS(R)) Society recommendations. Clin Nutr 31 : 783-800, 2012
 
2) Gustafsson UO, Scott MJ, Hubner M et al : Guidelines for perioperative care in elective colorectal surgery : Enhanced Recovery After Surgery (ERAS(R)) Society recommendations : 2018. World J Surg 43 : 659-695, 2019
 
3) Shichinohe T, Sasaki T, Kitashiro S et al : Impact of elemental diet on early recovery after laparoscopic colectomy : findings of a randomized controlled trial. Surg Today 47 : 166-173, 2017
PubMed
4) Weimann A, Braga M, Carli F et al : ESPEN practical guideline : clinical nutrition in surgery. Clin Nutr 40 : 4745-4761, 2021
 
5) Yoshida T, Homma S, Ichikawa N et al : Preoperative elemental diet before laparoscopic anterior resection in patients with advanced stenotic rectal cancer. J Anus Rectum Colon 5 : 395-404, 2021
PubMed
6) Ogata Y, Ishibashi N, Yamaguchi K et al : Preventive effects of amino-acid-rich elemental diet Elental(R) on chemotherapy-induced oral mucositis in patients with colorectal cancer : a prospective pilot study. Support Care Cancer 24 : 783-789, 2016
 
7) 術前絶飲食ガイドライン, 公益社団法人日本麻酔科学会, 2012 [https://anesth.or.jp/files/download/news/20120712.pdf]
 
8) Lobo DN, Hendry PO, Rodrigues G et al : Gastric emptying of three liquid oral preoperative metabolic preconditioning regimens measured by magnetic resonance imaging in healthy adult volunteers : a randomised double-blind, crossover study. Clin Natr 28 : 636-641. 2009
 
9) Kobayashi S, Segami K, Hoshino H et al : Risk factors for failure of early recovery from pancreatoduodenectomy despite the use of enhanced recovery after surgery protocols and a physical aging score to predict postoperative risks. J Hepatobiliary Pancreat Sci 25 : 231-239, 2018
 
10) Mori R, Matsuyama R, Taniguchi K et al : Efficacy of prolonged elemental diet therapy after pancreaticoduodenectomy for pancreatic ductal adenocarcinoma : A pilot prospective randomized trial (UMIN000004108). Clin Nutr ESPEN 34 : 116-124, 2019
PubMed
11) 二神幸恵, 瀬戸口智彦, 砂山健一ほか : 開腹結腸がん切除後早期における成分栄養剤ゼリーの有効性. 日本病院薬剤師会雑誌 51 : 211-215, 2015
Medical*Online
12) Waldhausen JH, Shaffrey ME, Skenderis BS 2nd et al : Gastrointestinal myoelectric and clinical patterns of recovery after laparotomy. Ann Surg 211 : 777-784, 1990
PubMed
13) Singer P, Blaser AR, Berger MM et al : ESPEN guideline on clinical nutrition in the intensive care unit. Clin Nutr 38 : 48-79, 2019
PubMed
P.40 掲載の参考文献
1) 安田秀喜, 高田忠敬, 天野穂高ほか : 経腸栄養と経静脈栄養の臨床比較試験からみた幽門輪温存膵頭十二指腸切除術後周術期栄養管理の問題点. 日本臨床外科学会雑誌 62 : 284, 2001
 
2) 荒木孝明, 土屋誉, 小針雅男ほか : 早期経腸栄養による膵頭十二指腸切除術後管理. 静脈経腸栄養 21 : 31-37, 2006
 
3) 膵癌診療ガイドライン 2019年版, 日本膵臓学会, 膵癌診療ガイドライン改訂委員会, 金原出版, 東京, 2019
 
4) Shen Y, Jin W : Early enteral nutrition after pancreatoduodenectomy : a meta-analysis of randomized controlled trials. Langenbecks Arch Surg 398 : 817-823, 2013
 
5) Adiamah A, Ranat R, Gomez D : Enteral versus parenteral nutrition following pancreaticoduodenectomy : a systematic review and meta-analysis. HPB (Oxford) 21 : 793-801, 2019
PubMed
6) Tanaka M, Heckler M, Mihaljevic AL et al : Meta-analysis of effect of routine enteral nutrition on postoperative outcomes after pancreatoduodenectomy. Br J Surg 106 : 1138-1146, 2019
PubMed
7) Guan H, Chen S, Huang Q : Effects of enteral immunonutrition in patients undergoing pancreaticoduodenectomy : a meta-analysis of randomized controlled trials. Ann Nutr Metab 74 : 53-61, 2019
 
8) Kang YK, Dong L, Ge Y et al : Short-term clinical outcomes of enteral nutrition versus parenteral nutrition after surgery for pancreatic cancer : a meta-analysis, Transl Cancer Res 8 : 1403-1411, 2019
PubMed
9) Cai J, Yang G, Tao Y et al : A meta-analysis of the effect of early enteral nutrition versus total parenteral nutrition on patients after pancreaticoduodenectomy. HPB (Oxford) 22 : 20-25, 2020
PubMed
10) Omori A, Tsunoda S, Nishigori T et al : Clinical benefits of routine feeding jejunostomy tube placement in patients undergoing esophagectomy. J Gastrointest Surg 26 : 733-741. 2022
PubMed
11) 三宅謙太郎, 松山隆生, 窪田硫富人ほか : 膵頭十二指腸切除後に経腸栄養を-行う vs 行わない-経腸栄養を行うの立場から. 臨床外科 75 : 689-694, 2020
 
12) Zhu X, Wu Y, Qiu Y et al : Comparative analysis of the efficacy and complications of nasojejunal and jejunostomy on patients undergoing pancreaticoduodenectomy. JPEN J Parenter Enteral Nutr 38 : 996-1002, 2014
 
13) Wiggins TF, DeLegge MH : Evaluation of a new technique for endoscopic nasojejunal feeding-tube placement. Gastrointest Endosc 63 : 590-595, 2006
PubMed
14) Baradi H, Walsh RM, Henderson JM et al : Postoperative jejunal feeding and outcome of pancreaticoduodenectomy. J Gastrointest Surg 8 : 428-433, 2004
PubMed
15) Nussbaum DP, Zani S, Penne K et al : Feeding jejunostomy tube placement in patients undergoing pancreaticoduodenectomy : an ongoing dilemma. J Gastrointest Surg 18 : 1752-1759.. 2014
PubMed
16) Mori R, Matsuyama R, Taniguchi K et al : Efficacy of prolonged elemental diet therapy after pancreaticoduodenectomy for pancreatic ductal adenocarcinoma : A pilot prospective randomized trial (UMIN000004108). Clin Nutr ESPEN 34 : 116-124, 2019
PubMed
17) 松本逸平, 吉田雄太, 川口晃平ほか : 膵頭十二指腸切除後に経腸栄養を-行う vs 行わない-経腸栄養を行わないの立場から. 臨床外科 75 : 689, 695-697, 2020
 
18) Matsugu Y, Ito K, Oshita A et al : Postoperative oral energy and protein intakes for an enhanced recovery after surgery program incorporating early enteral nutrition for pancreaticoduodenectomy : A retrospective study. JNutr Clin Pract 37 : 654-665, 2022
PubMed
19) Chen Z, Zhang Z, Lin B et al : Relationship between early oral intake post pancreaticoduodenectomy and chyle leakage : a retrospective cohort study. J Invest Surg 34 : 575-582, 2021
 
20) Melloul E, Lassen K, Roulin D et al : Guidelines for perioperative care for pancreatoduodenectomy : Enhanced Recovery After Surgery (ERAS) recommendations 2019. World J Surg 44 : 2056-2084, 2020
PubMed
P.45 掲載の参考文献
1) Ando N, Kato H, Igaki H et al : A randomized trial comparing postoperative adjuvant chemotherapy with cisplatin and 5-fluorouracil versus preoperative chemotherapy for localized advanced squamous cell carcinoma of the thoracic esophagus (JCOG9907). Ann Surg Oncol 19 : 68-74, 2012
 
2) 保谷芳行, 矢部三男, 渡部篤史ほか : 食道癌切除後乳糜胸の診断と治療. 日本外科系連合学会誌 39 : 627-633, 2014
 
3) Phang K, Bowman M, Phillips A et al : Review of thoracic duct anatomical variations and clinical implications. Clin Anat 27 : 637-644, 2014
PubMed
4) Takeuchi H, Miyata H, Ozawa S et al : Comparison of short-term outcomes between open and minimally invasive esophagectomy for esophageal cancer using a nationwide database in Japan. Ann Surg Oncol 24 : 1821-1827, 2017
PubMed
5) Wemyss-Holden SA, Launois B, Maddern GJ : Management of thoracic duct injuries after oesophagectomy. Br J Surg 88 : 1442-1448, 2001
PubMed
6) Chen S, Zhao Y, Chen H : Risk factors of chylothorax after esophagectomy. J Thorac Dis 11 : 1749-1752, 2019
 
7) Weijs TJ, Ruurda JP, Broekhuizen ME et al : Outcome of a step-up treatment strategy for chyle leakage after esophagectomy. Ann Thorac Surg 104 : 477-484, 2017
PubMed
8) Lagarde SM, Omloo JM, de Jong K et al : Incidence and management of chyle leakage after esophagectomy. Ann Thorac Surg 80 : 449-454, 2005
PubMed
9) Lin Y, Li Z, Li G et al : Selective en masse ligation of the thoracic duct to prevent chyle leak after esophagectomy. Ann Thorac Surg 103 : 1802-1807, 2017
 
10) Lei Y, Feng Y, Zeng B et al : Effect of prophylactic thoracic duct ligation in reducing the incidence of postoperative chylothorax during esophagectomy : a systematic review and meta-analysis. Thorac Cardiovasc Surg 66 : 370-375, 2018
 
11) Zhang C, Gong L, Wu W et al : Association between low-fat enteral nutrition after esophagectomy and a lower incidence of chyle leakage : a call for more and better evidence. Retrospective Clinical Research Report 48 : 1-13, 2020
 
12) Bryant AS, Minnich DJ, Wei B et al : The incidence and management of postoperative chylothorax after pulmonary resection and thoracic mediastinal lymph node dissection. Ann Thorac Surg 98 : 232-235, 2014
PubMed
13) Berger AC, Scott WJ, Freedman G et al : Morbidity and mortality are not increased after induction chemoradiotherapy followed by esophagectomy in patients with esophageal cancer. Semin Oncol 32 (6 Suppl 9) : S16-S20, 2005
PubMed
14) Gronnier C, Trechot B, Duhamel A et al : Impact of neoadjuvant chemoradiotherapy on postoperative outcomes after esophageal cancer resection : results of a European multicenter study. Ann Surg 260 : 764-770, 2014
PubMed
15) Ohkura Y, Ueno M, Shindoh J et al : Risk factors for postoperative chylothorax after radical subtotal esophagectomy. Ann Surg Oncol 25 : 2739-2746, 2018
PubMed
16) Miao L, Zhang Y, Hu H et al : Incidence and management of chylothorax after esophagectomy. Thorac Cancer 6 : 354-358, 2015
 
17) 小谷正彦, 山下昭 : リンパの生化学. 代謝 9 : 591-597, 1972
 
18) Kanzaki M, Sasano S, Murasugi M et al : Early endoscopic treatment of chylothorax develops after surgical treatment of chylothorax develops after surgical treatment of lung cancer patients. Jpn J Thorac Cardiovasc Surg 51 : 506-510, 2003
PubMed
19) Moro K, Koyama Y, Kosugi S et al : Low fat-containing elemental formula is effective for postoperative recovery and potentially useful for preventing chyle leak during postoperative early enteral nutrition after esophagectomy. Clin Nutr 35 : 1423-1428, 2016
PubMed
P.50 掲載の参考文献
1) Horiuchi A, Nakayama Y, Sakai R et al : Elemental diets may reduce the risk of aspiration pneumonia in bedridden gastrostomy-fed patients. Am J Gastroenterol 108 : 804-810, 2013
PubMed
2) Horiuchi A, Sakai R, Tamaki M et al : Gastric Emptying of Elemental Liquid Diets Versus Semisolid Diets in Bedridden Gastrostomy-fed Patients. J Clin Gastroenterol 53 : 373-378, 2019
PubMed

Part 3 IBDにおける成分栄養剤のこれまでとこれから

P.55 掲載の参考文献
1) Stephens RV, Randall HT : Use of concentrated, balanced, liquid elemental diet for nutritional management of catabolic states. Ann Surg 170 : 642-668, 1969
PubMed
2) Duke JH Jr, Yar H, Yar MS : Management of surgical nutritional complications in developing countries. Infusionsther Klin Ernahr Sonderh 3 : 15-23, 1975
PubMed
3) 樋渡信夫, 今野保敏, 小林和人ほか : 経腸栄養法の実際 炎症性腸疾患. 臨床外科 40 : 73-80, 1985
 
4) Hoffman FG : Regional ileitis (cicatrizing enteritis, Crohn's disease). Some considerations in its medical management and a note on the use of salazopyrine (azopyrin). Med Bull U S Army Eur Command Med Div 7 : 693-700, 1950
 
5) Brohee G : ACTH. cortisone or sodium salicylate in Crohn's disease ; therapeutic trial. Acta Gastroenterol Belg 14 : 39-45, 1951
PubMed
6) Brooke BN, Hoffmann DC, Swarbrick ET : Azathioprine for Crohn's disease. Lancet 2 : 612-614, 1969
PubMed
7) Matsueda K, Shoda R, Takazoe M et al : Therapeutic efficacy of cyclic home elemental enteral alimentation in Crohn's disease : Japanese cooperative Crohn's disease study. J Gastroenterol 30 (Suppl 8) : 91-94, 1995
 
8) Hiwatashi N : Enteral nutrition for Crohn's disease in Japan. Dis Colon Rectum 40 (10 Suppl) : S48-S53, 1997
 
9) Takagi S, Utsunomiya K, Kuriyama S et al : Effectiveness of an 'half elemental diet' as maintenance therapy for Crohn's disease : A randomized-controlled trial. Aliment Pharmacol Ther 24 : 1333-1340, 2006
PubMed
10) Takagi S, Utsunomiya K, Kuriyama S et al : Quality of life of patients and medical cost of 'half elemental diet' as maintenance therapy for Crohn's disease : secondary outcomes of a randomised controlled trial. Dig Liver Dis 41 : 390-394, 2009
PubMed
11) Akobeng AK, Thomas AG : Enteral nutrition for maintenance of remiss ion in Crohn's disease. Cochrane Database Syst Rev : CD005984, 2007
 
12) Tanaka T, Takahama K, Kimura T et al : Effect of concurrent elemental diet on infliximab treatment for Crohn's disease. J Gastroenterol Hepatol 21 : 1143-1149, 2006
PubMed
13) Hirai F, Ishihara H, Yada S et al : Effectiveness of concomitant enteral nutrition therapy and infliximab for maintenance treatment of Crohn's disease in adults. Dig Dis Sci 58 : 1329-1334, 2013
PubMed
14) Kamata N, Oshitani N, Watanabe K et al : Efficacy of concomitant elemental diet therapy in scheduled infliximab therapy in patients with Crohn's disease to prevent loss of response. Dig Dis Sci 60 : 1382-1388, 2015
PubMed
15) Sazuka S, Katsuno T, Nakagawa T et al : Concomitant use of enteral nutrition therapy is associated with sustained response to infliximab in patients with Crohn's disease. Eur J Clin Nutr 66 : 1219-1223, 2012
PubMed
16) Yamamoto T, Nakahigashi M, Umegae S et al : Prospective clinical trial : enteral nutrition during maintenance infliximab in Crohn's disease. J Gastroenterol 45 : 24-29, 2010
PubMed
17) Hisamatsu T, Kunisaki R, Nakamura S et al : Effect of elemental diet combined with infliximab dose escalation in patients with Crohn's disease with loss of response to infliximab : CERISIER trial. Intest Res 16 : 494-498, 2018
PubMed
18) Nguyen DL, Palmer LB, Nguyen ET et al : Specialized enteral nutrition therapy in Crohn's disease patients on maintenance infliximab therapy : a meta-analysis. Therap Adv Gastroenterol 8 : 168-175, 2015
PubMed
19) Hirai F, Takeda T, Takada Y et al : Efficacy of enteral nutrition in patients with Crohn's disease on maintenance anti-TNF-α antibody therapy : a meta-analysis. J Gastroenterol 55 : 133-141, 2020
 
20) Tsai L, Ma C, Dulai PS et al : Contemporary risk of surgery in patients with ulcerative colitis and crohn's disease : a meta-analysis of population-based cohorts. Clin Gastroenterol Hepatol 19 : 2031-2045, 2021
 
21) Yamamoto T, Nakahigashi M, Umegae S et al : Impact of long-term enteral nutrition on clinical and endoscopic recurrence after resection for Crohn's disease : a prospective, non-randomized, parallel, controllcd study. Aliment Pharmacol Ther 25 : 67-72, 2007
PubMed
22) Brennan GT, Ha I, Hogan C et al : Does preoperative enteral or parenteral nutrition reduce postoperative complications in Crohn's disease patients : a meta-analysis. Eur J Gastroenterol Hepatol 30 : 997-1002, 2018
PubMed
P.64 掲載の参考文献
1) 医薬品インタビューフォーム : 成分栄養剤エレンタール(R) 配合内服剤 (2022年8月改訂, 第7版)
 
2) 医薬品添付文書 : 成分栄養剤エレンタール(R) 配合内服剤 (2016年4月改訂, 第8版)
 
3) Driscoll RH Jr, Rosenberg IH : Total parenteral nutrition in inflammatory bowel disease. Med Clin North Am 62 : 185-201, 1978
PubMed
4) Fischer JE, Foster GS, Abel RM et al : Hyperalimentation as primary therapy for inflammatory bowel disease. Am J Surg 125 : 165-175, 1973
PubMed
5) Vogel CM, Corwin TR, Baue AE : Intravenous hyperalimentation. In the treatment of inflammatory diseases of the bowel. Arch Surg 108 : 460-467, 1974
PubMed
6) Voitk AJ, Echave V, Feller JH et al : Experience with elemental diet in the treatment of inflammatory bowel disease. Is this primary therapy? Arch Surg 107 : 329-333, 1973
PubMed
7) 樋渡信夫, 今野保敏, 小林和人ほか : Elemental dietによるクローン病の治療経験. 日本消化器内視鏡学会雑誌 24 : 578-584, 1982
 
8) 樋渡信夫, 今野保敏, 小林和人ほか : 経腸栄養法の実際-炎症性腸疾患. 臨床外科 40 : 73-80, 1985
 
9) Fuchigami T, Ohgushi H, Imamura K et al : Effects of total parenteral nutrition on colonic lesions in Crohn's disease : radiographic and endoscopic study. Gastroenterol Jpn 17 : 521-529, 1982
PubMed
10) Ostro MJ, Greenberg GR, Jeejeebhoy KN : Total parenteral nutrition and complete bowel rest in the management of Crohn's disease. JPEN J Parenter Enteral Nutr 9 : 280-287, 1985
PubMed
11) Jones VA : Comparison of total parenteral nutrition and elemental diet in induction of remission of Crohn's disease. Long-term maintenance of remission by personalized food exclusion diets. Dig Dis Sci32 (12 Suppl) : 100S-107S, 1987
 
12) O'Morain C, Segal AW, Levi AJ : Elemental diet as primary treatment of acute Crohn's disease : a controlled trial. Br Med J 288 : 1859-1862, 1984
 
13) Okada M, Yao T, Yamamoto T et al : Controlled trial comparing an elemental diet with prednisolone in the treatment of active Crohn's disease. Hepatogastroenterology 37 : 72-80, 1990
PubMed
14) 松枝啓, 正田良介, 梅田典嗣 : クローン病におけるHome hyperalimentationの意義. JJPEN 7 : 305-307, 1985
 
15) 福田能啓, 下山孝 : クローン病治療における高カロリー栄養. JJPEN 13 : 227-231, 1991
 
16) Takagi S, Utsunomiya K, Kuriyama S et al : Effectiveness of an 'half elemental diet' as maintenance therapy for Crohn's disease : a randomized-controlled trial. Aliment Pharmacol Ther 24 : 1333-1340, 2006
PubMed
17) Cani PD. Bibiloni R, Knauf C et al : Changes in gut microbiota control metabolic endotoxelnia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 57 : 1470-1481, 2008
PubMed
18) Devkota S, Wang Y, Musch MW et al : Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in I110-/- mice. Nature 487 : 104-108, 2012
 
19) Kawaguchi T, Mori M, Saito K et al : Food antigen-induced immune responses in Crohn's disease patients and experimental colitis mice. J Gastroenterol 50 : 394-405, 2015
PubMed
20) Andoh A, Takaya H, Araki Y et al : Medium- and long-chain fatty acids differentially modulate interleukin-8 secretion in human fetal intestinal epithelial cells. J Nutr 130 : 2636-2640, 2000
PubMed
21) Okada Y, Tsuzuki Y, Sato H et al : Trans fatty acids exacerbate dextran sodium sulphate-induced colitis by promoting the up-regulation of macrophage-derived proinflammatory cytokines involved in T hetper 17 cell polarization. Clin Exp Immunol 174 : 459-471, 2013
 
22) Fujiyama Y, Hokari R, Miura S et al : Butter feeding enhances TNF-alpha production from macrophages and lymphocyte adherence in murine small intestinal microvessels. J Gastroenterol Hepatol 22 : 1838-1845, 2007
PubMed
23) Fujimoto T, Imaeda H, Takahashi K et al : Decreased abundance of Faecalibacterium prausnitzii in the gut microbiota of Crohn's disease. J Gastroenterol Hepatol 28 : 613-619., 2013
PubMed
24) Atarashi K, Tanoue T, Oshima K et al : Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota. Nature 500 : 232-236, 2013
PubMed
25) Andou A, Hisamatsu T, Okamoto S et al : Dietary histidine ameliorates murine colitis by inhibition of proinflammatory cytokine production from macrophages. Gastroenterology 136 : 564-574, 2009
PubMed
26) Takamatsu M, Hirata A, Ohtaki H et al : IDO1 plays an immunosuppressive role in 2, 4. 6-trinitrobenzene sulfate-induced colitis in mice. J Immunol 191 : 3057-3064, 2013
PubMed
27) Hisamatsu T, Okamoto S. Hashimoto M et al : Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease. PLoS One 7 : e31131, 2012
PubMed
28) 潰瘍性大腸炎・クローン病診断基準・治療指針, 「難治性炎症性腸管障害に関する調査研究班」 (久松班) 令和3年度分担研究報告書, 2022
 
29) 炎症性腸疾患 (IBD) 診療ガイドライン 2020 改訂第2版, 日本消化器病学会編, 南江堂, 東京, 2020
 
30) 植木光彦, 松井敏幸, 山田美加ほか : 活動期Crohn病の経腸栄養療法-amino acid based dietとoligopeptide based dietによるrandomized controlled trial. 日本消化器病学会雑誌 91 : 1415-1425, 1994
 
31) 宗祐人, 櫻井俊弘, 松井敏幸ほか : 活動期クローン病患者に対する半消化態栄養剤 (Racol(R)) の短期的治療効果. 日本大腸肛門病学会雑誌 61 : 509-515, 2008
 
32) 中村志郎, 宮嵜孝子, 樋田信幸 : W3-3. 抗TNF-α抗体製剤で治療したクローン病二次無効例の実態と対応～粘膜治癒を目標としたreset TPNと経腸栄養療法の有効性も含めて～. 日本消化器病学会近畿支部例会プログラム・抄録集 106 : 68, 2017
Medical*Online
P.71 掲載の参考文献
1) Miyazaki C, Nagano K, Huang KC et al : Evaluation of economic burden with biologic treatments in Crohn's disease patients : a mirror image study using an insurance database in Japan. PLoS One 16 : e0254807, 2021
 
2) Bouguen G, Peyrin-Biroulet L : Surgery for adult Crohn's disease : what is the actual risk? Gut 60 : 1178-1181, 2011
PubMed
3) Qiu Y. Chen BL, Mao R et al : Systematic review with meta-analysis : loss of response and requirement of anti-TNFα dose intensification in Crohn's disease. J Gastroenterol 52 : 535-554. 2017
 
4) Ding NS, Hart A, De Cruz P : Systematic review : predicting and optimising response to anti-TNF therapy in Crohn's disease-algorithm for practical management. Aliment Pharmacol Ther 43 : 30-51, 2016
PubMed
5) Park KT, Colletti RB, Rubin DT et al : Health insurance paid costs and drivers of costs for patients with Crohn's disease in the United States. Am J Gastroenterol 111 : 15-23, 2016
PubMed
6) 潰瘍性大腸炎・クローン病診断基準・治療指針, 「難治性炎症性腸管障害に関する調査研究班」 (久松班) 令和3年度分担研究報告書, 2022
 
7) Tanaka T, Takahama K, Kimura T et al : Effect of concurrent elemental diet on infliximab treatment for Crohn's disease. J Gastroenterol Hepatol 21 : 1143-1149, 2006
PubMed
8) Hisamatsu T, Kunisaki R, Nakamura S et al : Effect of elemental diet combined with infliximab dose escalation in patients with Crohn's disease with loss of response to infliximab : CERISIER trial. Intest Res 16 : 494-498, 2018
PubMed
9) Sazuka S, Katsuno T, Nakagawa T et al : Concomitant use of enteral nutrition therapy is associated with sustained response to infliximab in patients with Crohn's disease. Eur J Clin Nutr 66 : 1219-1223, 2012
PubMed
10) Hirai F, Ishihara H, Yada S et al : Effectiveness of concomitant enteral nutrition therapy and infliximab for maintenance treatment of Crohn's disease in adults. Dig Dis Sci 58 : 1329-1334, 2013
PubMed
11) Kamata N, Oshitani N Watanabe K et al : Efficacy of concomitant elemental diet therapy in scheduled infliximab therapy in patients with Crohn's disease to prevent loss of response. Dig Dis Sci 60 : 1382-1388, 2015
PubMed
12) Sugita N, Watanabe K, Kamata N et al : Efficacy of a concomitant elemental diet to reduce the loss of response to adalimumab in patients with intractable Crohn's disease. J Gastroenterol Hepatol 33 : 631-637, 2018
PubMed
13) Yamamoto T, Nakahigashi M, Umegae S et al : Prospective clinical trial : enteral nutrition during maintenance infliximab in Crohn's disease. J Gastroenterol 45 : 24-29, 2010
PubMed
14) Hirai F, Ishida T, Takeshima F et al : Effect of a concomitant elemental diet with maintenance anti-tumor necrosis factor-α antibody therapy in patients with Crohn's disease : a multicenter, prospective cohort study. J Gastroenterol Hepatol 34 : 132-139, 2019
 
15) Nguyen DL, Palmer LB, Nguyen ET et al : Specialized enteral nutrition therapy in Crohn's disease patients on maintenance infliximab therapy : a meta-analysis. Therap Adv Gastroenterol 8 : 168-175, 2015
PubMed
16) Hirai F, Takeda T, Takada Y et al : Efficacy of enteral nutrition in patients with Crohn's disease on maintenance anti-TNF-alpha antibody therapy : a meta-analysis. J Gastroenterol 55 : 133-141, 2020
PubMed
P.76 掲載の参考文献
1) 新井勝大, 工藤孝広, 熊谷秀規ほか : 小児クローン病治療指針. 日本小児栄養消化器肝臓学会雑誌 33 : 90-109, 2019
Medical*Online
2) Ishige T, Tomomasa T, Tajiri H et al : Japanese physicians' attitudes towards enteral nutrition treatment for pediatric patients with Crohn's disease : a questionnaire survey. Intest Res 15 : 345-351, 2017
PubMed
3) van Rheenen PF, Aloi M, Assa A et al : The Medical Management of Paediatric Crohn's Disease : an ECCO-ESPGHAN Guideline Update. J Crohns Colitis 15 : 171-194, 2021
 
4) Swaminath A, Feathers A, Ananthakrishnan AN et al : Systematic review with meta-analysis : enteral nutrition therapy for the induction of remission in paediatric Crohn's disease. Aliment Pharmacol Ther 46 : 645-656, 2017
PubMed
5) Pigneur B, Lepage P, Mondot S et al : Mucosal Healing and Bacterial Composition in Response to Enteral Nutrition Vs Steroid-based Induction Therapy-A Randomised Prospective Clinical Trial in Children With Crohn's Diseasc. J Crohns Colitis 13 : 846-855, 2019
 
6) Lee D, Baldassano RN, Otley AR et al : Comparative effectiveness of nutritional and biological therapy in North American children with active Crohn's disease. Inflamm Bowel Dis 21 : 1786-1793, 2015
PubMed
7) Moriczi M, Pujol-Muncunill G, Martin-Masot R et al : Predictors of response to exclusive enteral nutrition in newly diagnosed Crohn's disease in children : PRESENCE study from SEGHNP. Nutrients 12 : 1012, 2020
 
8) Ashton JJ, Gavin J, Beattie RM : Exclusive enteral nutrition in Crohn's disease : evidence and practicalities. Clin Nutr 38 : 80-89, 2019
PubMed
9) Miele E, Shamir R, Aloi M et al : Nutrition in pediatric inflammatory bowel disease : a position paper on behalf of the Porto Inflammatory Bowel Disease Group of the European Society of Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr 66 : 687-708, 2018
 
10) Nguyen DL, Palmer LB, Nguyen ET et al : Specialized enteral nutrition therapy in Crohn's disease patients on maintenance inflixilnab therapy : a meta-analysis. Therap Adv Gastroenterol 8 : 168-175, 2015
PubMed
11) Gkikas K, Gerasimidis K, Milling S et al : Dietary strategies for maintenance of clinical remission in inflammatory bowel diseases : Are we there yet? Nutrients 12 : 2018, 2020
PubMed
12) Verburgt CM, Ghiboub M, Benninga MA et al : Nutritional therapy strategies in pediatric Crohn's disease. Nutrients 13 : 212, 2021
PubMed
13) Lawley M, Wu JW, Navas-Lopez VM et al : Global variation in use of enteral nutrition for pediatric Crohn disease. J Pediatr Gastroenterol Nutr 67 : e22-e29, 2018
PubMed
14) 南部隆亮 : 栄養療法および食事療法. 小児内科 52 : 1231-1234, 2020
Medical*Online
15) Levine A, Wine E, Assa A et al : Crohn's disease exclusion diet plus partial enteral nutrition induces sustained remission in a randomized controlled trial. Gastroenterology 157 : 440-450, 2019
 
P.82 掲載の参考文献
1) Forbes A, Escher J, Hebuterne X et al : ESPEN guideline : Clinical nutrition in inflammatory bowel disease. Clin Nutr 36 : 321-347, 2017
 
2) Yamamoto T, Carvello M, Lightner AL et al : Up-to-date surgery for ulcerative colitis in the era of biologics. Expert Opin Biol Ther 20 : 391-398, 2020
PubMed
3) Yamamoto T, Lightner AL, Spinelli A et al : Perioperative management of ileocecal Crohn's disease in the current era. Expert Rev Gastroenterol Hepatol 14 : 843-855, 2020
PubMed
4) Yamamoto T, Teixeira FV, Saad-Hossne R et al : Anti-TNF and postoperative complications in abdominal Crohn's disease surgery. Curr Drug Targets 20 : 1339-1348, 2019
PubMed
5) Iesalnieks I, Kilger A, Glass H et al : Perforating Crohn's ileitis : delay of surgery is associated with inferior postoperative outcome. Inflamm Bowel Dis 16 : 2125-2130, 2010
PubMed
6) Cohen BL, FleShner P, Kane SV et al : Prospective cohort study to investigate the safety of preoperative tumor necrosis factor inhibitor exposure in patients with inflammatory bowel disease undergoing intra-abdominal surgery. Gastroenterology 163 : 204-221, 2022
PubMed
7) Yamamoto T, Shimoyama T, Umegae S et al : Impact of Preoperative Nutritional Status on the Incidence Rate of Surgical Complications in patients With Inflammatory Bowel Disease With Vs Without Preoperative Biologic Therapy : A Case-Control Study. Clin Transl Gastroenterol 10 : e00050, 2019
 
8) Weimann A, Braga M, Harsanyi L et al : ESPEN guidelines on enteral nutrition : surgery including organ transplantation. Clin Nutr 25 : 224-244, 2006
PubMed
9) Brennan GT, Ha I, Hogan et al : Does preoperative enteral or parenteral nutrition reduce postoperative complications in Crohn's disease patients : a meta-analysis. Eur J Gastroenterol Hepatol 30 : 997-1002, 2018
PubMed
10) Yamamoto T, Nakahigashi M, Shimoyama T et al : Does preoperative enteral nutrition reduce the incidence of surgical complications in patients with Crohn's disease? A case-matched study. Colorectal Dis 22 : 554-561, 2020
PubMed
P.86 掲載の参考文献
1) Ameho CK, Adjei AA, Harrison EK et al : Prophylactic effect of dietary glutamine supplementation on interleukin 8 and tumour necrosis factor α production in trinitrobenzene sulphonic acid induced colitis. Gut 41 : 487-493, 1997
 
2) Peterson JW, Boldogh I, Popov VL et al : Anti-inflammatory and antisecretory potential of histidine in Salmonella-challenged mouse small intestine. Lab Invest 78 : 523-534, 1998
PubMed
3) Tsune I, Ikejima K, Hirose M et al : Dietary glycine prevents chemical-induced experimental colitis in the rat. Gastroenterology 125 : 775-785, 2003
PubMed
4) 中村志郎, 松本誉之, 原順一ほか : クローン病の新たな緩解維持療法intermittent total enteral nutrition : i-TEN療法の臨床的検討. 消化器科 28 : 504-509, 1999
 
5) 薮添朋子, 山本由喜子, 灘井城ほか : 間欠的完全経腸栄養療法導入時におけるクローン病患者の食事摂取状況. 栄養学雑誌 60 : 231-237, 2002
Medical*Online
6) Lee D, Albenberg L, Compher C et al : Diet in the pathogenesis and treatment of inflammatory bowel diseases. Gastroenterology 148 : 1087-1106, 2015
PubMed
7) Ordas I, Mould DR, Feagan BG et al : Anti-TNF monoclonal antibodies in inflammatory bowel disease : pharmacokinetics-based dosing paradigms. Clin Pharmacol Ther 91 : 635-646, 2012
PubMed
8) Kamata N, Oshitani N, Watanabe K et al : Efficacy of concomitant elemental diet therapy in scheduled infliximab therapy in patients with Crohn's disease to prevent loss of response. Dig Dis Sci 60 : 1382-1388, 2015
PubMed
9) Sugita N, Watanabe K, Kamata N et al : Efficacy of a concomitant elemental diet to reduce the loss of response to adalimumab in patients with intractable Crohn's disease. J Gastroenterol Hepatol 33 : 631-637, 2018
PubMed
P.91 掲載の参考文献
1) Harris JA, Benedict FG : A Biometric Study of Human Basal Metabolism. Proc Natl Acad Sci U S A 4 : 370-373, 1918
PubMed
2) Takaoka A, Sasaki M, Nakanishi N et al : Nutritional Screening and Clinical Outcome in Hospitalized Patients with Crohn's Disease. Ann Nutr Metab 71 : 266-272, 2017
PubMed
3) Forbes A, Escher J, Hebuterne X et al : ESPEN guideline : Clinical nutrition in inflammatory bowel disease. Clin Nutr 36 : 321-347, 2017
 
4) Gibson PR, Shepherd SJ : Personal view : food for thought--western lifestyle and susceptibility to Crohn's disease. The FODMAP hypothesis. Aliment Pharmacol Ther 21 : 1399-1409, 2005
PubMed
5) Racine A, Carbonnel F, Chan SS et al : Dietary Patterns and Risk of Inflammatory Bowel Disease in Europe : Results from the EPIC Study. Inflamm Bowel Dis 22 : 345-354, 2016
 
6) Roberts CL, Keita AV, Duncan SH et al : Translocation of Crohn's disease Escherichia coli across M-cells : contrasting effects of soluble plant fibres and emulsifiers. Gut 59 : 1331-1339, 2010
PubMed
7) Desai MS. Seekatz AM, Koropatkin NM et al : A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility. Cell 167 : 1339-1353.e21, 2016
 
8) Thornton JR, Emmett PM, Heaton KW : Diet and Crohn's disease : characteristics of the pre-illness diet. Br Med J 2 : 762-764, 1979
PubMed
9) Ananthakrishnan AN, Khalili H, Konijeti GG et al : A prospective study of long-term intake of dietary fiber and risk of Crohn's disease and ulcerative colitis. Gastroenterology 145 : 970-977, 2013
PubMed
10) Jantchou P, Morois S, Clavel-Chapelon F et al : Animal protein intake and risk of inflammatory bowel disease : The E3N prospective study. Am J Gastroenterol 105 : 2195-2201, 2010
PubMed
11) Jowett SL, Seal CJ, Pearce MS et al : Influence of dietary factors on the clinical course of ulcerative colitis : a prospective cohort study. Gut 53 : 1479-1484, 2004
PubMed
12) Diether NE, Willing BP : Microbial Fermentation of Dietary Protein : An Important Factor in Diet-Microbe-Host Interaction. Microorganisms 7 : 19, 2019
 
13) Degagne E, Pandurangan A, Bandhuvula P et al : Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs. J Clin Invest 124 : 5368-5384, 2014
PubMed
14) Liang J, Nagahashi M, Kim EY et al : Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer. Cancer Cell 23 : 107-120, 2013
PubMed
15) Shoda R, Matsueda K, Yamato S et al : Epidemiologic analysis of Crohn disease in Japan : increased dietary intake of n-6 polyunsaturated fatty acids and animal protein relates to the increased incidence of Crohn disease in Japan. Am J Clin Nutr 63 : 741-745, 1996
 
16) Feagan BG, Sandborn WJ, Mittmann U et al : Omega-3 free fatty acids for the maintenance of remission in Crohn disease : the EPIC Randomized Controlled Trials. JAMA 299 : 1690-1697, 2008
PubMed
17) Miura S, Imaeda H, Shiozaki H et al : Increased proliferative response of lymphocytes from intestinal lymph during long chain fatty acid absorption. Immunology 78 : 142-146, 1993
PubMed
18) Hoshimoto A, Suzuki Y, Katsuno T et al : Caprylic acid and medium-chain triglycerides inhibit IL-8 gene transcription in Caco-2 cells : comparison with the potent histone deacetylase inhibitor trichostatin A. Br J Pharmacol 136 : 280-286, 2002
PubMed
19) Mazzucchelli L, Hauser C, Zgraggen K et al : Expression of interleukin-8 gene in inflammatory bowel disease is related to the histological grade of active inflammation. Am J Pathol 144 : 997-1007, 1994
 
20) Dixon LJ, Kabi A, Nickerson KP et al : Combinatorial effects of diet and genetics on inflammatory bowel disease pathogenesis. Inflamm Bowel Dis 21 : 912-922, 2015
PubMed
21) Pendyala S, Walker JM, Holt PR : A high-fat diet is associated with endotoxemia that originates from the gut. Gastroenterology 142 : 1100-1101.e2, 2012
 
22) Costea I, Mack DR, Lemaitre RN et al : Interactions between the dietary polyunsaturated fatty acid ratio and genetic factors determine susceptibility to pediatric Crohn's disease. Gastroenterology 146 : 929-931, 2014
PubMed
23) Laudisi F, Stolfi C, Monteleone G : Impact of Food Additives on Gut Homeostasis. Nutrients 11 : 2334, 2019
PubMed
24) Lewis JD, Abreu MT : Diet as a Trigger or Therapy for Inflammatory Bowel Diseases. Gastroenterology 152 : 398-414.e6, 2017
PubMed
25) Chassaing B, Koren O, Goodrich JK et al : Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome. Nature 519 : 92-96, 2015
PubMed
26) Levine A, Rhodes JM, Lindsay JO et al : Dietary Guidance From the International Organization for the Study of Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol 18 : 1381-1392, 2020
 
27) Kawaguchi T, Mori M, Saito K et al : Food antigen-induced immune responses in Crohn's disease patients and experimental colitis mice. J Gastroenterol 50 : 394-405, 2015
PubMed
28) Bamba T, Shimoyama T, Sasaki M et al : Dietary fat attenuates the benefits of an elemental diet in active Crohn's disease : a randomized, controlled trial. Eur J Gastroenterol Hepatol 15 : 151-157, 2003
PubMed
29) Zachos M, Tondeur M, Griffiths AM : Enteral nutritional therapy for induction of remission in Crohn's disease. Cochrane Database Syst Rev4 : CD000542, 2018
 
30) Andou A, Hisamatsu T, Okamoto S et al : Dietary histidine ameliorates murine colitis by inhibition of proinflammatory cytokine production from macrophages. Gastroenterology 136 : 564-574.e2, 2009
 
31) Akobeng AK, Elawad M, Gordon M : Glutamine for induction of remission in Crohn's disease. Cochrane Database Syst Rev 2 : CD007348, 2016
PubMed
P.98 掲載の参考文献
1) Chang JT : Pathophysiology of inflammatory bowel diseases. N Engl J Med 383 : 2652-2664, 2020
PubMed
2) Lees CW, Barrett JC, Parkes M et al : New IBD genetics : common pathways with other diseases. Gut 60 : 1739-1753, 2011
PubMed
3) Yang J, Pu J, Lu S et al : Species-level analysis of human gut microbiota with metataxonomics. Front Microbiol 11 : 2029, 2020
PubMed
4) Honda K, Littman DR : The microbiome in infectious disease and inflammation. Annu Rev Immunol 30 : 759-795, 2012
PubMed
5) Zheng D, Liwinski T, Elinav E : Interaction between microbiota and immunity in health and disease. Cell Res 30: 492-506, 2020
PubMed
6) Marchesi JR, Adams DH, Fava F et al : The gut microbiota and host health : a new clinical frontier. Gut 65 : 330-339, 2016
 
7) Sun M, Wu W, Liu Z et al : Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases. J Gastroenterol 52 : 1-8, 2017
PubMed
8) Atarashi K, Tanoue T, Oshima K et al : Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota. Nature 500 : 232-236, 2013
PubMed
9) Atarashi K, Tanoue T, Ando M et al : Th17 cell induction by adhesion of microbes to intestinal epithelial cells. Cell 163 : 367-380, 2015
PubMed
10) Pittayanon R, Lau JT, Leontiadis GI et al : Differences in gut microbiota in patients with vs without inflammatory bowel diseases : a systematic review. Gastroenterology 158 : 930-946.e931, 2020
 
11) Lee M, Chang EB : Inflammatory bowel diseases (IBD) and the microbiome-searching the crime scene for clues. Gastroenterology 160 : 524-537, 2021
 
12) Hedin CR, McCarthy NE, Louis P et al : Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's discase and their unaffected siblings. Gut 63 : 1578-1586, 2014
 
13) Fujimoto T, Imaeda H, Takahashi K et al : Decreased abundance of Faecalibacterium prausnitzii in the gut microbiota of Crohn's disease. J Gastroenterol Hepatol 28 : 613-619, 2013
PubMed
14) Takahashi K, Nishida A, Fujimoto T et al : Reduced abundance of butyrate-producing bacteria species in the fecal microbial community in Crohn's disease. Digestion 93 : 59-65, 2016
PubMed
15) Vester-Andersen MK, Mirsepasi-Lauridscn HC, Prosberg MV et al : Increased abundance of proteobacteria in aggressive Crohn's disease seven years after diagnosis. Sci Rep 9 : 13473, 2019
 
16) Peterson DA, Frank DN, Pace NR et al : Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases. Cell Host Microbe 3 : 417-427, 2008
PubMed
17) Palmela C, Chevarin C, Xu Z et al : Adherent-invasive Escherichia coli in inflammatory bowel dlsease. Gut 67 : 574-587, 2018
PubMed
18) Chervy M, Barnich N, Denizot J : Adherent-Invasive E. coli : update on the lifestyle of a troublemaker in Crohn's disease. Int J Mol Sci 21 : 3734, 2020
PubMed
19) Takagi S. Utsunomiya K, Kuriyama S et al : Effectiveness of an 'half elemental diet' as maintenance therapy for Crohn's disease : a randomized-controlled trial. Aliment Pharmacol Ther 24 : 1333-1340, 2006
PubMed
20) Okada M, Yao T, Yamamoto T et al : Controlled trial comparing an elemental diet with prednisolone in the treatment of active Crohn's disease. Hepatogastroenterology 37 : 72-80, 1990
PubMed
21) Hirai F, Ishida T, Takeshima F et al : Effect of a concomitant elemental diet with maintenance anti-tumor necrosis factor-α antibody therapy in patients with Crohn's disease : a multicenter, prospective cohort study. J Gastroenterol Hepatol 34 : 132-139, 2019
 
22) Andou A, Hisamatsu T, Okamoto S et al : Dietary histidine ameliorates murine colitis by inhibition of proinflammatory cytokine production from macrophages. Gastroenterology 136 : 564-574.e562, 2009
 
23) Ameho CK, Adjei AA, Harrison EK et al : Prophylactic effect of dietary glutamine supplementation on interleukin 8 and tumour necrosis factor alpha production in trinitrobenzene sulphonic acid induced colitis. Gut 41 : 487-493, 1997
PubMed
24) Coburn LA, Gong X, Singh K et al : L-arginine supplementation improves responses to injury and inflammation in dextran sulfate sodium colitis. PLoS One 7 : e33546, 2012
 
25) Giris M, Erbil Y, Dogru-Abbasoglu S et al : The effect of heme oxygenase-1 induction by glutamine on TNBS-induced colitis. The effect of glutamine on TNBS colitis. Int J Colorectal Dis 22 : 591-599, 2007
PubMed
26) Kajiura T, Takeda T, Sakata S et al : Change of intestinal microbiota with elemental diet and its impact on therapeutic effects in a murine model of chronic colitis. Dig Dis Sci 54 : 1892-1900, 2009
 
27) Liu X, Beaumont M, Walker F et al : Beneficial effects of an amino acid mixture on colonic mucosal healing in rats. Inflamm Bowel Dis 19 : 2895-2905, 2013
 
28) Ren W, Yin J, Wu M et al : Serum amino acids profile and the beneficial effects of L-arginine or L-glutamine supplementation in dextran sulfate sodium colitis. PLoS One 9 : e88335, 2014
PubMed
29) Tsune I, Ikejima K, Hirose M et al : Dietary glycine prevents chemical-induced experimental colitis in the rat. Gastroenterology 125 : 775-785. 2003
PubMed
30) Xue H, Sufit AJD, Wischmeyer PE : Glutamine therapy improves outcome of in vitro and in vivo experimental colitis models. JPEN J Parenter Enteral Nutr 35 : 188-197, 2011
PubMed
31) Miyoshi J, Saito D, Nakamura M et al : Half-elemental diet shifts the human intestinal bacterial compositions and metabolites : a pilot study with healthy individuals. Gastroenterol Res Pract 2020 : 7086939, 2020
PubMed
32) Andoh A, Inoue R, Kawada Y et al : Elemental diet induces alterations of the gut microbial community in mice. J Clin Biochem Nutr 65 : 118-124, 2019
PubMed

Part 4 がん支持療法における成分栄養剤のこれまでとこれから

P.106 掲載の参考文献
1) Japanese Gastric Cancer Association : Japanese gastric cancer treatment guidelines 2014 (ver. 4). Gastric Cancer 20 : 1-19, 2017
 
2) Sakuramoto S, Sasako M, Yamaguchi T et al : Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine. N Engl J Med 357 : 1810-1820, 2007
 
3) Aoyama T, Yoshikawa T, Shirai J et al : Body weight loss after surgery is an independent risk factor for continuation of S-1 adjuvant chemotherapy for gastric cancer. Ann Surg Oncol 20 : 2000-2006, 2013
PubMed
4) Aoyama T, Sato T, Maezawa Y et al : Postoperative weight loss leads to poor survival through poor S-1 efficacy in patients with stage II/III gastric cancer. Int J Clin Oncol 22 : 476-483, 2017
 
5) Aoyama T, Kawabe T, Fujikawa H et al : Loss of lean body mass as an independent risk factor for continuation of S-1 adjuvant chemotherapy for gastric cancer. Ann Surg Oncol 22 : 2560-2566, 2015
PubMed
6) Aoyama T, Yoshikawa T, Maezawa Y et al : The postoperative lean body mass loss at one month leads to a poor survival in patients with locally advanced gastric cancer. J Cancer 10 : 2450-2456, 2019
PubMed
7) Koterazawa Y, Oshikiri T, Takiguchi G et al : Severe weight loss after minimally invasive oesophagectomy is associated with poor survival in patients with oesophageal cancer at 5 years. BMC Gastroenterol 20 : 407, 2020
PubMed
8) Mayanagi S, Tsubosa Y, Omae K et al : Negative impact of skeletal muscle wasting after neoadjuvant chemotherapy followed by surgery on survival for patients with thoracic esophageal cancer. Ann Surg Oncol 24 : 3741-3747, 2017
PubMed
9) Ida S, Hiki N, Cho H et al : Randomized clinical trial comparing standard diet with perioperative oral immunonutrition in total gastrectomy for gastric cancer. Br J Surg 104 : 377-383, 2017
PubMed
10) Imamura H, Nishikawa K, Kishi K et al : Effects of an oral elemental nutritional supplement on post-gastrectomy body weight loss in gastric cancer patients : a randomized controlled clinical trial. Ann Surg Oncol 23 : 2928-2935, 2016
PubMed
11) Kimura Y, Nishikawa K, Kishi K et al : Long-term effects of an oral elemental nutritional supplement on post-gastrectomy body weight loss in gastric cancer patients (KSES002). Ann Gastroenterol Surg 3 : 648-656, 2019
PubMed
12) Qiu M, Zhou YX, Jin Y et al : Nutrition support can bring survival benefit to high nutrition risk gastric cancer patients who received chemotherapy. Support Care Cancer 23 : 1933-1939, 2015
PubMed
13) Bozzetti F : Does nutrition support during chemotherapy increase long-term survival of cancer patients? Lessons from the past and future perspectives. Support Care Cancer 29 : 7269-7277, 2021
PubMed
14) Lalla RV, Bowen J, Barasch A et al : MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer 120 : 1453-1461, 2014
PubMed
15) Tanaka Y, Shimokawa T, Harada K et al : Effectiveness of elemental diets to prevent oral mucositis associated with cancer therapy : A meta-analysis. Clin Nutr ESPEN 49 : 172-180, 2022
PubMed
P.111 掲載の参考文献
1) Aoyama T, Yoshikawa T, Shirai J et al : Body weight loss after surgery is an independent risk factor for continuation of S-1 adjuvant chemotherapy for gastric cancer. Ann Surg Oncol 20 : 2000-2006, 2013
PubMed
2) Aoyama T, Sato T, Maezawa Y et al : Postoperative weight loss leads to poor survival through poor S-1 efficacy in Patients with stage II/III gastric cancer. Int J Clin Oncol 22 : 476-483, 2017
 
3) Lee HH, Park JM, Song KY et al : Survival impact of postoperative body mass index in gastric cancer patients undergoing gastrectomy. Eur J Cancer 52 : 129. -137, 2016
 
4) Imamura H, Nishikawa K, Kishi K et al : Effects of an oral elemental nutritional supplement on post-gastrectomy body weight loss in gastric cancer patients : a randomized controlled clinical trial. Ann Surg Oncol 23 : 2928-2935, 2016
PubMed
5) Kimura Y, Nishikawa K, Kishi K et al : Long-term effects of an oral elemental nutritional supplement on post-gastrectomy body weight loss in gastric cancer patients (KSES002). Ann Gastroenterol Surg 3 : 648-656, 2019
PubMed
6) 吉川貴己, 青山徹, 林勉ほか : 胃癌術後の体重/体組成変動とその意義. 外科と代謝・栄養 49 : 205-211, 2015
Medical*Online
7) 中田浩二 : 胃切除後障害の今日的話題. 日本臨床外科学会雑誌 77 : 1007-1022, 2016
 
8) Lee JH, Hyung WJ, Kim HI et al : Method of reconstruction governs iron metabolism after gastrectomy for patients with gastric cancer. Ann Surg 258 : 964-969, 2013
PubMed
9) Aoyama T, Kawabe T, Fujikawa H et al : Loss of lean body mass as an independent risk factor for continuation of S-1 adjuvant chemotherapy for gastric cancer. Ann Surg Oncol 22 : 2560-2566, 2015
PubMed
10) Nakazono M, Aoyama T, Hayashi T et al : Comparison of the dietary intake loss between total and distal gastrectomy for gastric cancer. In Vivo 35 : 2369-2377, 2021
PubMed
11) Ida S, Hiki N, Cho H et al : Randomized clinical trial comparing standard diet with perioperative oral immunonutrition in total gastrectomy for gastric cancer. Br J Surg 104 : 377-383, 2017
PubMed
12) Aoyama T, Yoshikawa T, Ida S et al : Effects of perioperative Eicosapentaenoic acid-enriched oral nutritional supplement on lean body mass after total gastrectomy for gastric cancer. J Cancer 10 : 1070-1076. 2019
PubMed
13) Miyazaki Y, Omori T, Fujitani K et al : Oral nutritional supplements versus a regular diet alone for body weight loss after gastrectomy : a phase 3, multicenter, open-label randomized controlled trial. Gastric Cancer 24 : 1150-1159, 2021
PubMed
14) Kobayashi D, Ishigure K. Mochizuki Y et al : Multi-institutional prospective feasibility study to explore tolerability and efficacy of oral nutritional supplements for patients with gastric cancer undergoing gastrectomy (CCOG1301). Gastric Cancer 20 : 718-727, 2017
PubMed
15) Haba Y, Fujimura T, Oyama K et al : Effect of oral branched-chain amino acids and glutamine supplementation on skeletal muscle atrophy after total gastrectomy in rat model. J Surg Res 243 : 281-288, 2019
 
P.116 掲載の参考文献
1) 胃癌治療ガイドライン 医師用 2021年7月改訂 第6版, 日本胃癌学会, 金原出版, 東京, 2021
 
2) Kim SJ, Kim YJ, Kim JH et al : Safety, compliance, and predictive parameters for dosage modification in adjuvant S-1 chemotherapy for gastric cancer. Cancer Sci 104 : 116-123, 2013
PubMed
3) Bonadonna G, Valagussa P, Moliterni A et al : Adjuvant cyclophosphamide, methotrexate, and fluorouracil in node-positive breast cancer : the results of 20 years of follow-up. N Engl J Med 332 : 901-906, 1995
PubMed
4) Aoyama T, Yoshikawa T, Shirai J et al : Body weight loss after surgery is an independent risk factor for continuation of S-1 adjuvant chemotherapy for gastric cancer. Ann Surg Oncol 20 : 2000-2006, 2013
PubMed
5) Aoyama T, Sato T, Maezawa Y et al : Postoperative weight loss leads to poor survival through poor S-1 efficacy in patients with stage II/III gastric cancer. Int J Clin Oncol 22 : 476-483, 2017
 
6) Imamura H, Nishikawa K, Kishi K et al : Effects of an oral elemental nutritional supplement on post-gastrectomy body weight loss in gastric cancer patients : a randomized controlled clinical trial. Ann Surg Oncol 23 : 2928-2935, 2016
PubMed
7) Imamura H, Matsuyama J, Nishikawa K et al : Effects of an oral elemental nutritional supplement in gastric cancer patients with adjuvant S-1 chemotherapy after gastrectomy : A multicenter, open-label, single-arm, prospective phase II study (OGSG1108). Ann Gastroenterol Surg 5 : 776-784, 2021
PubMed
8) Sakuramoto S, Sasako M, Yamaguchi T et al : Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine. N Engl J Med 357 : 1810-1820, 2007
 
9) Taiho Pharmaceutical Co., Ltd. Study report. No. 717, 2017
PubMed
10) Toyomasu Y, Mochiki E, Yanai M et al : A prospective pilot study of an elemental nutritional supplement for prevention of oral mucositis during S-1 adjuvant chemotherapy for gastric cancer. Surg Oncol 29 : 97-101, 2019
 
P.121 掲載の参考文献
1) Tamakoshi A, Yatsuya H, Lin Y et al : BMI and all-cause mortality among Japanese older adults : findings from the Japan collaborative cohort study. Obesity (Silver Spring) 18 : 362-369, 2010
PubMed
2) 静脈経腸栄養ガイドライン 第3版, 日本静脈経腸栄養学会, 照林社, 東京, 2013
 
3) Arends J, Baracos V, Bertz H et al : ESPEN expert group recommendations for action against cancer-related malnutrition. Clin Nutr 16 : 1187-1196, 2017
 
4) Friesen DE, Baracos VE, Tuszynski JA : Modeling the energetic cost of cancer as a result of altered energy metabolism : implications for cachexia. Theor Biol Med Model 12 : 17, 2015
PubMed
5) Hawley JA. Lessard SJ : Exercise training-induced improvements in insulin action. Acta Physiol (Oxf) 192 : 127-135, 2008
PubMed
6) Suetsugu T, Tanaka Y, Banno S et al : Intranodal lymphangiography for chyle leakage after esophagectomy : A case report. Mol Clin Oncol 12 : 343-349, 2020
PubMed
7) Sato Y, Tanaka Y, Imai T et al : Chylothorax after esophagectomy treated with inguinal intranodal lymphangiography and transvenous retrograde thoracic duct embolization. Clin J Gastroenterol 14 : 969-974, 2021
PubMed
8) Kranzfelder M, Buchler P, Lange K et al : Treatment options for squamous cell cancer of the esophagus : asystematic review of the literature. J Am Coll Surg 210 : 351-359, 2010
 
9) Tanaka Y, Yoshida K, Sanada Y et al : Biweekly docetaxel, cisplatin, and 5-fluorouracil (DCF) chemotherapy for advanced esophageal squamous cell carcinoma : a phase I dose-escalation study. Cancer Chemother Pharmacol 66 : 1159-1165, 2010
PubMed
10) Tanaka Y, Yoshida K, Yamada A et al : Phase II trial of biweekly docetaxel, cisplatin, and 5-fluorouracil chemotherapy for advanced esophageal squamous cell carcinoma. Cancer Chemother Pharmacol 77 : 1143-1152, 2016
PubMed
11) Tanaka Y, Yoshida K, Osada S et al : Docetaxel, nedaplatin, and S-1 (DGS) chemotherapy for advanced esophageal carcinoma : a phase I dose-escalation study. Anticancer Res 31 : 4589-4597, 2011
PubMed
12) Tanaka Y, Yoshida K, Tanahashi T et al : Phase II trial of neoadjuvant chemotherapy with docetaxel, nedaplatin, and S1 for advanced esophageal squamous cell carcinoma. Cancer Sci 107 : 764-772, 2016
PubMed
13) Coeffier M, Marion R, Ducrotte P et al : Modulating effect of glutamine on IL-1bda-induced cytokine production by human gut. Clin Nutr 22 : 407-413, 2003
 
14) Choi K, Lee SS, Oh SJ et al : The effect of oral glutamine on 5-fluorouracil/leucovorin-induced mucositis/stomatitis assessed by intestinal permeability test. Clin Nutr 26 : 57-62. 2007
 
15) 小山諭, 田中善宏, 田原信ほか : がん化学療法の完遂を目指して-新しい支持療法の概念と実践-. Pharma Medica 29 : 201-208, 2011
Medical*Online
16) Tanaka Y, Takahashi T, Yamaguchi K et al : Elemental diet plus glutamine for the prevention of mucositis in esophageal cancer patients receivingchemotherapy : a feasibility study. Support Care Cancer 24 : 933-941, 2016
PubMed
17) Mao JJ, Ismaila N, Bao T et al : Integrative medicine for pain management in oncology : Society for Integrative Oncology-ASCO Guideline. J Clin Oncol 40 : 3998-4024, 2022
 
18) Tanaka Y, Ueno T, Yoshida N et al : The effect of an elemental diet on oral mucositis of esophageal cancer patients treated with DCF chemotherapy : a multi-center prospective feasibility study (EPOC study). Esophagus 15 : 239-248, 2018
PubMed
19) Tanaka Y, Ueno T, Yoshida N et al : Is oral mucositis occurring during chemotherapy for esophageal cancer patients correctly judged? EPOC observational cohort study. Anticancer Res 39 : 4441-4448, 2019
PubMed
20) Tanaka Y, Takeuchi H, Nakashima Y ct a/: Effects of an elemental diet to reduce adverse events in patients with esophageal cancer receiving docetaxel/cisplatin/t-fluorouracil : phase III randomized controlled trial-EPOC 2 (JFMC49-1601-C5). ESMO Open 6 : 100277, 2021
 
21) Tanaka Y, Shimokawa T, Harada K et al : Effectiveness of elemental diets to prevent oral mucositis associated with cancer therapy : A meta-analysis. Clin Nutr ESPEN 49 : 172-180, 2022
PubMed
22) Tanaka Y, Sato Y, Suetsugu T et al : How to maintain nutritional status after esophagectomy via the Tanaka method. J Cancer Metastasis Treat 7 : 59, 2021
 
P.128 掲載の参考文献
1) 国立研究開発法人国立がん研究センター : 最新がん統計, がん情報サービス [https://ganjoho.jp/reg_stat/statistics/stat/summary.html]
 
2) Sonis ST : A biological approach to mucositis. J Support Oncol 2 : 21-32, 2004
PubMed
3) Tanaka Y, Shimokawa T, Harada K et al : Effectiveness of elemental diets to prevent oral mucositis associated with cancer therapy : A meta-analysis. Clin Nutr ESPEN 49 : 172-180, 2022
PubMed
4) Harada K, Ferdous T, Horinaga D et al : Efficacy of elemental diet on prevention for chemoradiotherapy-induced oral mucositis in patients with oral squamous cell carcinoma. Support Care Cancer 24 : 953-959, 2016
PubMed
5) Harada K, Minami H, Ferdous T et al : The Elental(R) elemental diet for chemoradiotherapy-induced oral mucositis : a prospective study in patients with oral squamous cell carcinoma. Mol Clin Oncol 10 : 159-167, 2019
 
6) Chen G, Shi J, Qi M et al : Glutamine decreases intestinal nuclear factor kappa B activity and pro-inflammatory cytokine expression after traumatic brain injury in rats. Inflamm Res 57 : 57-64, 2008
PubMed

Part 5 膵疾患における成分栄養剤のこれまでとこれから

P.136 掲載の参考文献
1) 片岡慶正, 阪上順一, 泰井敦子ほか : 疼痛を有する慢性膵炎治療に成分栄養剤 (ED) は有効か. 難治性膵疾患に関する調査研究 平成19年度総括・分担研究報告書 : 222-226, 2008
 
2) Ito T, Igarashi H, Niina Y et al : Management of pain in chronic pancreatitis with home elemental diet ingestion. JOP 11 : 648-649, 2010
PubMed
3) Kataoka K, Sakagami J, Hirota M et al : Effects of oral ingestion of the elemental diet in patients with painful chronic pancreatitis in the real-life setting in Japan. Pancreas 43 : 451-457, 2014
PubMed
4) 慢性膵炎診療ガイドライン2015 改訂第2版, 日本消化器病学会編, 南江堂, 東京, 2015, pp. 61-62
 
5) 慢性膵炎診療ガイドライン 2021 改訂第3版, 日本消化器病学会編, 南江堂, 東京, 2021. pp. 71-72
 
6) Maruki J, Sai JK, Watanabe S : Efficacy of low-fat diet against dyspepsia associated with nonalcoholic mild pancreatic disease diagnosed using the Rosemont criteria. Pancreas 42 : 49-52, 2013
PubMed
7) Ikeura T, Takaoka M, Uchida K et al : Beneficial effect of low-fat elemental diet therapy on pain in chronic pancreatitis. Int J Chronic Dis 2014 : 862091, 2014
 
8) Castineira-Alvarino M, Lindkvist B, Luaces-Regueira M et al : The role of high fat diet in the development of complications of chronic pancreatitis. Clin Nutr 32 : 830-836, 2013
PubMed
9) O'Brien SJ, Omer E : Chronic pancreatitis and nutrition therapy. Nutr Clin Pract 34 (Suppl 1) : S13-S26, 2019
 
P.141 掲載の参考文献
1) Williams JA : Intracellular signaling mechanisms activated by cholecystokinin-regulating synthesis and secretion of digestive enzymes in pancreatic acinar cells. Annu Rev Physiol 63 : 77-97, 2001
PubMed
2) Love JA, Yi E, Smith TG : Autonomic pathways regulating pancreatic exocrine secretion. Auton Neurosci 133 : 19-34, 2007
 
3) Liddle RA : Cholecystokinin cells. Annu Rev Physiol 59 : 221-242, 1997
PubMed
4) Ji B, Bi Y, Simeone D et al : Human pancreatic acinar cells lack functional responses to cholecystokinin and gastrin. Gastroenterology 121 : 1380-1390, 2001
PubMed
5) Singer MV, Niebergall-Roth E : Secretion from acinar cells of the exocrine pancreas : role of enteropancreatic reflexes and cholecystokinin. Cell Biol Int 33 : 1-9, 2009
PubMed
6) Murphy JA, Criddle DN, Sherwood M et al : Direct activation of cytosolic Ca2+ signaling and enzyme secretion by cholecystokinin in human pancreatic acinar cells. Gastroenterology 135 : 632-641, 2008
PubMed
7) McLaughlin J, Grazia Luca M, Jones MN et al : Fatty acid chain length determines cholecystokinin secretion and effect on human gastric motility. Gastroenterology 116 : 46-53, 1999
PubMed
8) Matzinger D, Degen L, Drewe J et al : The role of long chain fatty acids in regulating food intake and cholecystokinin release in humans. Gut 46 : 688-693, 2000
PubMed
9) Owyang C, Logsdon CD : New insights into neurohormonal regulation of pancreatic secretion. Gastroenterology 127 : 957-969, 2004
PubMed
10) Iwai K, Fukuoka S, Fushiki T et al : Purification of a trypsin-sensitive cholecystokinin releasing peptide from pancreatic juice. J Biol Chem 262 : 8956-8959, 1987
PubMed
11) Jin HO, Song CW, Chang TM et al : Roles of gut hormones in negative-feedback regulation of pancreatic exocrine secretion in humans. Gastroenterology 107 : 1828-1834, 1994
 
12) Chey WY, Shay H, Schuman CR : External pancreatic secretion in diabetes mellitus. Ann Intern Med 59 : 812-821, 1963
 
13) Lee KY, Krusch D, Zhou L et al : Effect of endogenous insulin on pancreatic exocrine secretion in perfused dog pancreas. Pancreas 11 : 190-195, 1995
PubMed
14) Watanabe S, Shiratori K, Takeuchi T et al : Release of cholecystokinin and exocrine pancreatic secretion in response to an elemental diet in human subjects. Dig Dis Sci 31 : 919-924, 1986
 
15) 塩賀太郎, 高山敬子, 田原純子ほか : 重症急性膵炎に対する経鼻胃管チューブ下早中期経腸栄養療法の有用性. 膵臓 32 : 806-811, 2017
Medical*Online
16) Blair EL, Brown JC, Harper AA et al : A gastric phase of pancreatic secretion. J Physiol 184 : 812-824, 1966
PubMed
P.146 掲載の参考文献
1) Sommer H, Kasper H : Effect of the nitrogen components of a peptide diet and the analogous amino acids on pancreatic secretion in the human. Z Gastroenterol 20 : 681-687, 1982
 
2) O'Keefe SJ, Lee RB, Anderson FP et al : Physiological effects of enteral and parenteral feeding on pancreaticobiliary secretion in humans. Am J Physiol Gastrointest Liver Physiol 284 : G27-G36, 2003
PubMed
3) 急性膵炎診療ガイドライン 2021 第5版, 急性膵炎診療ガイドライン 2021 改訂出版委員会, 金原出版, 東京, 2021
 
4) 静脈経腸栄養ガイドライン 第3版, 日本静脈経腸栄養学会, 照林社, 東京, 2013
 
5) Horibe M, Nishizawa T, Suzuki H et al : Timing of oral refeeding in acute pancreatitis : a systematic review and meta-analysis. United European Gastroenterol J 4 : 725-732, 2016
PubMed
6) McClave SA, Taylor BE, Martindale RG et al : Guidelines for the provision and assessment of nutrition support therapy in the adult critically Ill patient : Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A. S. P. E. N.). JPEN J Parenter Enteral Nutr 40 : 159-211, 2016
 
7) Ledder O, Duvoisin G, Lekar M et al : Early feeding in acute pancreatitis in children : a randomized controlled trial. Pediatrics 146 : e20201149, 2020
PubMed
8) Arvanitakis M, Ockenga J, Bezmarevic M et al : ESPEN guideline on clinical nutrition in acute and chronic pancreatitis. Clin Nutr 39 : 612-631, 2020
PubMed
9) 阪上順一 : 急性膵炎・重症急性膵炎. 今日の治療指針 2023年版, in press, 2023
 
10) Lakananurak N, Gramlich L : Nutrition management in acute pancreatitis : clinical practice consideration. World J Clin Cases 8 : 1561-1573, 2020
PubMed
11) Machicado JD, Wani S, Quingalahua E et al : Practice patterns and adherence to nutrition guidelines in acute pancreatitis : an international physician survey. Pancreatology 21 : 642-648, 2021
PubMed
12) Jablonska B, Mrowiec S : Nutritional support in patients with severe acute pancreatitis-current standards. Nutrients 13 : 1498, 2021
PubMed
13) Tran A, Fernando SM. Rochwerg B et al : Prognostic factors associated with development of infected necrosis in patients with acute necrotizing or severe pancreatitis-a systematic review and meta-analysis. J Trauma Acute Care Surg 92 : 940-948, 2022
PubMed
14) Endo A, Shiraishi A, Fushimi K et al : Comparative effectiveness of elemental formula in the early enteral nutrition management of acute pancreatitis : a retrospective cohort study. Ann Intensive Care 8 : 69, 2018
PubMed
15) 栗山とよ子 : 膵疾患の栄養管理. 静脈経腸栄養 26 : 713-722, 2011
 
16) Bruno MJ, Haverkort EB, Tytgat GN et al : Maldigestion associated with exocrine pancreatic insufficiency : implications of gastrointestinal physiology and properties of enzyme preparations for a cause-related and patient-tailored treatment. Am J Gastroenterol 90 : 1383-1393, 1995
PubMed
17) Singh S, Midha S, Singh N et al : Dietary counseling versus dietary supplements for malnutrition in chronic pancreatitis : a randomized controlled trial. Clin Gastroenterol Hepatol 6 : 353-359, 2008
PubMed
18) 阪上順一 : 慢性膵炎における栄養管理. 臨床栄養 136 : 601-606, 2020
Medical*Online
19) Kataoka K, Sakagami J, Hirota M et al : Effects of oral ingestion of the elemental diet in patients with painful chronic pancreatitis in the real-life setting in Japan. Pancreas 43 : 451-457, 2014
PubMed
20) 慢性膵炎診療ガイ ドライン 2021 改訂第3版, 日本消化器病学会, 南江堂, 東京, 2021
 
21) 片岡慶正, 阪上順一, 保田宏明ほか : 難治性膵疾患に関する調査研究 慢性膵炎疼痛対策としての経腸栄養療法の検証と標準化. 難治性膵疾患に関する調査研究平成27年度 総括・分担研究報告書 (厚生労働科学研究費補助金難治性疾患等政策研究事業 (難治性疾患政策研究事業)) : 202-209, 2016
 
22) Kawaguchi Y, Lin JC, Kawashima Y et al : Relationship between pain and plasma amino acid levels in chronic pancreatitis. JOP 16 : 53-57, 2015
PubMed
23) Kawaguchi Y, Ogawa M, Ito H et al : Alterations in plasma amino acid levels in alcoholic chronic pancreatitis in Japanese. Digestion 86 : 155-160, 2012
PubMed
P.151 掲載の参考文献
1) Kuroda T, Kumagi T, Yokota T et al : Improvement of long-term outcomes in pancreatic cancer and its associated factors within the gemcitabine era : a collaborative retrospective multicenter clinical review of 1,082 patients. BMC Gastroenterol 13 : 134, 2013
 
2) Emanuel A, Krampitz J, Rosenberger F et al : Nutritional interventions in pancreatic cancer : a systematic review. Cancers (Basel) 14 : 2212, 2022
PubMed
3) Arends J, Bodoky G, Bozzetti F et al : ESPEN guidelines on enteral nutrition : non-surgical oncology. Clin Nutr 25 : 245-259, 2006
PubMed
4) 中村陽介, 廣岡芳樹, 伊藤彰浩ほか : 切除不能進行膵癌例に対する栄養療法の有用性. 膵臓 27 : 649-655, 2012
Medical*Online
5) 畔元信明, 熊木天児, 黒田太良ほか : 当科で経過をおえた膵癌stage IVb死亡症例における予後因子の検討. 愛媛医学 32 : 15-18, 2013
 
6) 熊木天児, 竹治智, 宮田英樹ほか : 化学療法を受ける切除不能進行膵癌患者に対する成分栄養剤エレンタール内服の有用性. 膵臓 34 : A158, 2019
Medical*Online
7) Mori R, Matsuyama R, Taniguchi K et al : Efficacy of prolonged elemental diet therapy after pancreaticoduodenectomy for pancreatic ductal adenocarcinoma : A pilot prospective randomized trial (UMIN000004108). Clin Nutr ESPEN 34 : 116-124, 2019
PubMed
8) Fearon K, Strasser F, Anker SD et al : Definition and classification of cancer cachexia : an international consensus. Lancet Oncol 12 : 489-495, 2011
PubMed
9) Evans WJ, Morley JE, Argiles J et al : Cachexia : a new definition. Clin Nutr 27 : 793-799, 2008
PubMed
10) Iglesia D, Avci B, Kiriukova M et al : Pancreatic exocrine insufficiency and pancreatic enzyme replacement therapy in patients with advanced pancreatic cancer : A systematic review and meta-analysis. United Eoropean Gastroenterol J 8 : 1115-1125, 2020
 
11) Landers A, Donaldson F, Brown H et al : The impact of pancreatic enzyme replacement therapy on patients with advanced pancreatic adenocarcinoma : a systematic review and narrative synthesis. Pancreas 51 : 405-414, 2022
PubMed

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