肝疾患診療に役立つ 肝線維化評価テキスト

出版社: 文光堂
著者:
発行日: 2017-09-19
分野: 臨床医学:内科  >  肝/胆/膵
ISBN: 9784830621000
電子書籍版: 2017-09-19 (第1版第1刷)
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B型・C型肝炎,脂肪肝などの肝疾患において,肝線維化は病気の進行度や発癌リスクの予測をする上でもっとも重要なファクターである.しかし,現在,肝線維化評価のゴールドスタンダードである肝生検は侵襲性とサンプリングエラーなどの問題がある.本書では,肝生検にかわり,非侵襲的に肝全体の線維化の程度を評価できる有用な検査法として期待されるデバイスや線維化マーカー,スコアリングの概要から臨床への応用について,第一線の専門家が余すところなく解説した.

目次

  • 肝疾患診療に役立つ 肝線維化評価テキスト

    ―目次―

    第1章 肝線維化評価の臨床的意義

    第2章 肝線維化の非侵襲的評価方法
     1 肝線維化スコアリング(Fib-4 index,APRI,FibroIndex など)
     2 バイオマーカー
      1)血清線維化マーカー
      2)M2BPGi
      3)ELF score
     3 遺伝子
     4 超音波elastography
      1)Transient elastography(TE)
      2)Real-time tissue elastography(RTE)
      3)Shear wave elastography
     5 MR elastography
     6 MR laparoscopy

    第3章 臨床への展開
     1 非侵襲的手法の組み合わせによる肝線維化評価
     2 肝癌のリスクを予測する
     3 食道胃静脈瘤の存在を予測する
     4 治療が必要なB型肝炎を見分ける
     5 C型肝炎ウイルス排除後の病態を見極める
     6 自己免疫性肝疾患の病態を診断する
     7 脂肪肝の中からNASHを見分ける
     8 肝生検で得られる付加的情報とは

この書籍の参考文献

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本参考文献は電子書籍掲載内容を元にしております。

第1章 肝線維化評価の臨床的意義

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第2章 肝線維化の非侵襲的評価方法

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第3章 臨床への展開

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