こんなにも面白い医学の世界　からだのトリビア教えます

出版社： 羊土社
著者：
発行日： 2018-03-01
分野： 医学一般  >  医学一般
ISBN： 9784758118248
電子書籍版： 2018-03-01 （第1刷）
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マリンスポーツと納豆アレルギーの意外な関係性とは？秀吉の兵糧攻めにはある疾患が隠されていた！？など，身近に潜む医学の雑学「トリビア」満載の1冊．へぇーそうだったんだ！と思わず誰かに教えたくなること必至！

目次

  • 1．火薬が心臓病を治す？
    2．吸血鬼は感染症だった？
    3. αグルコシダーゼ阻害薬（経口血糖降下薬）とおならの話
    4. 新生児黄疸はどうして必要なの？
    5. イヌイットの血はさらさら？
    6. 秀吉の兵糧攻め
    7. 〆のラーメンが欲しくなるのはなぜ？
    8. 喫煙はからだにいい？
    9. 他人の便で治療？
    10. 高山病の予防・治療薬 アセタゾラミド
    11. 虫垂は無用の長物か？
    12. 四谷怪談のお岩さんがもられた毒とは？
    13. 宇宙飛行士が吸う空気
    14. 七面鳥を食べると眠くなる？
    15. 食事の後に運動するとわき腹が痛くなるのはなぜ？
    16. CAさんには乳がんが多い？
    17. ３秒ルールは本当か？
    18. 弁慶の立ち往生
    19. ジェットコースターのあとの頭痛
    20. 醤油を一気飲みしたらどうなる？
    21. 独眼竜正宗にステロイド
    22. ブタの臓器を人間に
    23. アイスクリーム頭痛
    24. 海で魚に刺されたら
    25. POKEMONという名のタンパク
    26. 中華料理店症候群
    27. 美容院卒中症候群
    28. フッ素ってやばいの？
    29. 人はなぜキスをするのか？
    30. 救急外来のジンクス
    31. ハイムリッヒ先生のハイムリッヒ法 初体験
    32. テレビゲームが疾患を生む？
    33. 「目散る」アルコール
    34. 心臓の穴は片頭痛を起こす？
    35. 氷をバリバリかじる人は病気？
    36. バンジージャンプで失明？
    37. マリンスポーツと納豆アレルギーの意外な関係
    38. 医者はどこへ行くのか？
    39. ゴッホの絵が黄色っぽい理由
    40. ヘリウムガスを使った宴会芸に注意

この書籍の参考文献

参考文献のリンクは、リンク先の都合等により正しく表示されない場合がありますので、あらかじめご了承下さい。

本参考文献は電子書籍掲載内容を元にしております。

1 火薬が心臓病を治す ?

P.7 掲載の参考文献
1) Ignarro LJ, et al:Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci USA, 84:9265-9269, 1987
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2) Murad F:What are the molecular mechanisms for the antiproliferative effects of nitric oxide and cGMP in vascular smooth muscle? Circulation, 95:1101-1103, 1997
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2 吸血鬼は感染症だった ?

P.9 掲載の参考文献
1) Gomez-Alonso J:Rabies:a possible explanation for the vampire legend. Neurology, 51:856-859, 1998
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2) Investigation of rabies infections in organ donor and transplant recipients--Alabama, Arkansas, Oklahoma, and Texas, 2004. MMWR Morb Mortal Wkly Rep, 53:586-589, 2004
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3 αグルコシダーゼ阻害薬 ( 経口血糖降下薬 ) とおならの話

P.11 掲載の参考文献
1) Chiasson JL, et al:Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance:the STOP-NIDDM trial. JAMA, 290:486-494, 2003
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2) Hanefeld M, et al:Acarbose reduces the risk for myocardial infarction in type 2 diabetic patients:meta-analysis of seven long-term studies. Eur Heart J, 25:10-16, 2004
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3) Suzuki Y, et al:Are the effects of alpha-glucosidase inhibitors on cardiovascular events related to elevated levels of hydrogen gas in the gastrointestinal tract? FEBS Lett, 583:2157-2159, 2009
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4) Sun Q, et al:Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats. Cardiovasc Res, 94:144-153, 2012
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4 新生児黄疸はどうして必要なの ?

P.13 掲載の参考文献
1) Yeo KL, et al:Outcomes of extremely premature infants related to their peak serum bilirubin concentrations and exposure to phototherapy. Pediatrics, 102:1426-1431, 1998
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2) Heyman E, et al:Retinopathy of prematurity and bilirubin. N Engl J Med, 320:256, 1989
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3) Matsumoto N, et al:Effectiveness of bovine gallstone (Goou) and bear gall powder (Yutan) on chronic liver diseases:a preliminary report. Tokai J Exp Clin Med, 20:9-16, 1995
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5 イヌイットの血はさらさら ?

P.15 掲載の参考文献
1) Dyerberg J, et al:Eicosapentaenoic acid and prevention of thrombosis and atherosclerosis? Lancet, 2(8081):117-119, 1978
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2) Yokoyama M, et al:Japan EPA lipid intervention study (JELIS) lnvestigators:Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients OELIS):a randomised open-label, blinded endpoint analysis. Lancet, 369(9567):1090-1098, 2007
PubMed

6 秀吉の兵糧攻め

P.17 掲載の参考文献
1) De Silva A, et al:Attitudes to NICE guidance on refeeding syndrome. BMJ, 337:a680, 2008
 
2) Mehanna HM, et al:Refeeding syndrome:what it is, and how to prevent and treat it. BMJ, 336:1495-1498, 2008
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7 〆のラーメンが欲しくなるのはなぜ ?

P.19 掲載の参考文献
1) Gibson EM & Tingen MS:Nursing care for diabetic patients with alcohol-induced hypoglycemia. J Emerg Nurs, 24(2):165-168, 1998
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2) Facchini F, et al:Light-to-moderate alcohol intake is associated with enhanced insulin sensitivity. Diabetes Care, 17(2):115-119, 1994
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8 喫煙はからだにいい ?

P.21 掲載の参考文献
1) Fratiglioni L & Wang HX:Smoking and Parkinson's and Alzheimer's disease:review of the epidemiological studies. Behav Brain Res, 113:117-120, 2000
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2) Baron JA:Cigarette smoking and Parkinson's disease. Neurology, 36:1490-1496, 1986
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3) Ryter SW & Otterbein LE:Carbon monoxide in biology and medicine. Bioessays, 26:270-280, 2004
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9 他人の便で治療 ?

P.23 掲載の参考文献
1) van Nood E, et al:Duodenal infusion of donor feces for recurrent clostridium difficile. N Engl J Med, 368:407-415, 2013
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2) Kassam Z, et al:Fecal microbiota transplantation for clostridium difficile infection:Systematic review and meta-analysis. Am J Gastroenterol, 108:500-508, 2013
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3) Colman RJ & Rubin DT:Fecal microbiota transplantation as therapy for inflammatory bowel disease:A systematic review and meta-analysis. J Crohns Colitis, 8:1569-1581, 2014
PubMed

11 虫垂は無用の長物か ?

P.27 掲載の参考文献
1) Randal Bollinger R, et al:Biofilms in the large bowel suggest an apparent function of the human vermiform appendix. J Theor Biol, 249(4):826-831, 2007
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2) Masahata K, et al:Generation of colonic IgA-secreting cells in the caecal patch. Nat Commun, 5:3704, 2014
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3) Okazaki K, et al:A patient with improvement of ulcerative colitis after appendectomy. Gastroenterology, 119(2):502-506, 2000
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4) Matsushita M, et al:Appendix is a priming site in the development of ulcerative colitis. World J Gastroenterol, 11(31):4869-4874, 2005
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5) Ward WH, et al:Clostridium difficile colitis:is severity increased with previous appendectomy? Am Surg, 79(8):E258-259, 2013
 

12 四谷怪談のお岩さんがもられた毒とは ?

P.29 掲載の参考文献
1) Chan TY.:Aconite poisoning. Clin Toxicol (Phila), 47(4):279-285, 2009
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2) 照井克俊ほか:トリカブト中毒患者30症例の不整脈症状を中心とした特徴と治療に関する臨床的検討. 日救急医会誌, 24:857-863, 2013
 

13 宇宙飛行士が吸う空気

P.31 掲載の参考文献
1) Schoenfeld MP, et al:Hydrogen therapy may reduce the risks related to radiation-induced oxidative stress in space flight. Med Hypotheses, 76:117-118, 2011
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2) Schoenfeld MP, et al:A hypothesis on biological protection from space radiation through the use of new therapeutic gases as medical counter measures. Med Gas Res. 2:8, 2012
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14 七面鳥を食べると眠くなる ?

P.33 掲載の参考文献
1) Ganguly S, et al:Control of melatonin synthesis in the mammalian pineal gland:the critical role of serotonin acetylation. Cell Tissue Res, 309(1):127-137, 2002
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2) Fukushige H, et al:Effects of tryptophan-rich breakfast and light exposure during the daytime on melatonin secretion at night. J Physiol Anthropol, 33:33, 2014
 

15 食事の後に運動するとわき腹が痛くなるのはなぜ ?

P.35 掲載の参考文献
1) Roshdy MS, et al:Effect of food intake on liver and spleen volume:Assessment with single photon emission computed tomography. Acad Radiol, 4:193-196, 1997
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2) Sandler MP, et al:Dynamic fluctuations in blood and spleen radioactivity:Splenic contraction and relation to clinical radionuclide volume calculations. J Am Coll Cardiol, 3:1205-1211, 1984
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16 CAさんには乳がんが多い ?

P.37 掲載の参考文献
1) Hammer GP, et al:Mortality from cancer and other causes in commercial airline crews:a joint analysis of cohorts from 10 countries. Occup Environ Med, 71(5):313-322, 2014
 
2) Tokumaru O, et al:Incidence of cancer among female flight attendants:a meta-analysis. J Travel Med, 13(3):127-132, 2006
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3) Irgens A, et al:Pregnancy outcome among offspring of airline pilots and cabin attendants. Scand J Work Environ Health, 29(2):94-99, 2003
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4) Kaji M, et al:Mortality experience of cockpit crewmembers from Japan Airlines. Aviat Space Environ Med, 64(8):748-750, 1993
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17 3秒ルールは本当か ?

P.39 掲載の参考文献
1) Dawson P, et al:Residence time and food contact time effects on transfer of Salmonella Typhimurium from tile, wood and carpet:testing the five-second rule. J Appl Microbiol, 102(4):945-953, 2007
 

18 弁慶の立ち往生

P.41 掲載の参考文献
1) Heller AR, et al.:Rigor mortis - a definite sign of death? Anasthesiol Intensivmed Notfallmed Schmerzther, 40(4):225-229, 2005
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2) Kobayashi M, et al.:Onset of rigor mortis is earlier in red muscle than in white muscle. Int J Legal Med, 113(4):240-243, 2000
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19 ジェットコースターのあとの頭痛

P.43 掲載の参考文献
1) Pfister BJ, et al.:Head motions while riding roller coasters:implications for brain injury. Am J Forensic Med Pathol, 30(4):339-345, 2009
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2) Bo-Abbas Y & Bolton CF:Roller-coaster headache. N Engl J Med, 332(23):1585, 1995
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3) Fukutake T, et al.:Roller coaster headache and subdural hematoma. Neurology, 54(1):264, 2000
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4) Rutsch S, et al.:Roller coaster-associated subarachnoid hemorrhage--report of 2 cases. J Neurol Sci, 315(1-2):164-166, 2012
 
5) Schievink WI, et al.:Rollercoaster headache due to spinal cerebrospinal fluid leak. Lancet, 347(9012):1409, 1996
PubMed

20 醤油を一気飲みしたらどうなる ?

P.45 掲載の参考文献
1) Yamazaki M, et al.:An autopsy case of salt poisoning from drinking a large quantity of shoyu (Japanese soy sauce). Leg Med (Tokyo), 2(2):84-87, 2000
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2) Turk EE, et al.:Fatal hypernatremia after using salt as an emetic--report of three autopsy cases. Leg Med (Tokyo), 7(1):47-50, 2005
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3) Carlberg DJ, et al.:Survival of acute hypernatremia due to massive soy sauce ingestion. J Emerg Med, 45(2):228-231, 2013
PubMed

21 独眼竜正宗にステロイド

P.47 掲載の参考文献
1) Chang GC & Young LH:Sympathetic ophthalmia. Semin Ophthalmol, 26:316-320, 2011
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2) Mahi-Brown CA, et al:Evidence for active immunological regulation in prevention of testicular autoimmune disease independent of the blood-testis barrier. Am J Reprod Immunol Microbiol, 16:165-170, 1988
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3) Sakamoto Y, et al:Testicular injury induces cell-mediated autoimmune response to testis. J Urol, 153:1316-1320, 1995
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22 ブタの臓器を人間に

P.49 掲載の参考文献
1) Chen G, et al:Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys. Nat Med, 11:1295-1298, 2005
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2) Cooper DK, et al:First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes-Chapter 4:pre-clinical efficacy and complication data required to justify a clinical trial. Xenotransplantation, 23:46-52, 2016
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23 アイスクリーム頭痛

P.51 掲載の参考文献
1) Fuh JL, et al:Ice-cream headache--a large survey of 8359 adolescents. Cephalalgia, 23:977-981, 2003
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2) Kaczorowski M & Kaczorowski J:Ice cream evoked headaches (ICE-H) study:randomised trial of accelerated versus cautious ice cream eating regimen. BMJ, 325:1445-1446, 2002
 
3) Raskin NH & Knittle SC:Ice cream headache and orthostatic symptoms in patients with migraine. Headache, 16:222-225, 1976
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4) Bird N, et al:Ice cream headache--site, duration, and relationship to migraine. Headache, 32:35-38, 1992
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24 海で魚に刺されたら

P.53 掲載の参考文献
1) 公益財団法人日本中毒情報センター 保健師・薬剤師・看護師向け中毒情報【魚刺傷】Ver.1.00:http://www.j-poison-ic.or.jp/ippan/M70022_0100_2.pdf
 
2) Auerbach PS:Marine envenomations. N Engl J Med, 325:486-493, 1991
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3) Hashimoto A, et al:Incorrect first aid treatment information about stonefish envenomation on medical websites. Chudoku Kenkyu, 26:292-294, 2013
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25 POKEMONという名のタンパク

P.55 掲載の参考文献
1) Maeda T, et al:The transcription factor Pokemon:a new key player in cancer pathogenesis. Cancer Res, 65:8575-8578, 2005
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2) Maeda T, et al:Role of the proto-oncogene Pokemon in cellular transformation and ARF repression. Nature, 433:278-285, 2005
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3) Simonite T:Pokemon blocks gene name. Nature, 438:897, 2005
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4) Maclean K:Humour of gene names lost in translation to patients. Nature, 439:266, 2006
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26 中華料理店症候群

P.57 掲載の参考文献
1) Kwok RH:Chinese-restaurant syndrome. N Engl J Med, 278:796, 1968
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2) Schaumburg HH, et al:Monosodium L-glutamate:its pharmacology and role in the Chinese restaurant syndrome. Science, 163:826-828, 1969
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3) Walker R & Lupien JR:The safety evaluation of monosodium glutamate. J Nutr, 130:1049S-1052S, 2000
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4) Gauzere BA, et al:A new chinese restaurant syndrome:the 'chinese fondue' carbon monoxide mass intoxication. Crit Care, 3:55, 1999
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27 美容院卒中症候群

P.59 掲載の参考文献
1) Weintraub MI.:Beauty parlor stroke syndrome:report of five cases. JAMA, 269:2085-2086, 1993
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2) Foye PM, et al.:Pain, dizziness, and central nervous system blood flow in cervical extension:vascular correlations to beauty parlor stroke syndrome and salon sink radiculopathy. Am J Phys Med Rehabil, 81:395-399, 2002
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3) Hanus SH, et al:Vertebral artery occlusion complicating yoga exercises. Arch Neurol, 34:574-575, 1977
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4) Zangbar B, et al.:Beauty parlor stroke syndrome:a rare entity in a trauma patient. Am Surg, 81:E120-122, 2015
 

28 フッ素ってやばいの ?

P.61 掲載の参考文献
1) Caravati EM:Acute hydrofluoric acid exposure. Am J Emerg Med, 6(2):143-150, 1988
PubMed

29 人はなぜキスをするのか ?

P.63 掲載の参考文献
1) Wlodarski R & Dunbar RI:Menstrual cycle effects on attitudes toward romantic kissing. Hum Nat, 24:402-413, 2013
PubMed
2) Hendrie CA & Brewer G:Kissing as an evolutionary adaptation to protect against human cytomegalovirus-like teratogenesis. Med Hypotheses, 74:222-224, 2010
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30 救急外来のジンクス

P.65 掲載の参考文献
1) Kuriyama A, et al:Impact of Attending Physicians' Comments on Residents' Workloads in the Emergency Department:Results from Two J (^o^) PAN Randomized Controlled Trials. PLoS One, 11:e0167480, 2016
 
2) Ahn A, et al:"We're jinxed"--are residents' fears of being jinxed during an on-call day founded? Am J Med, 112:504, 2002
 
3) Thompson DA & Adams SL:The full moon and ED patient volumes:unearthing a myth. Am J Emerg Med, 14:161-164, 1996
 
4) Lo BM, et al:Answering the myth:use of emergency services on Friday the 13th. Am J Emerg Med, 30:886-889, 2012
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31 ハイムリッヒ先生のハイムリッヒ法 初体験

P.67 掲載の参考文献
1) Chae HS, et al:Two cases of steakhouse syndrome associated with nutcracker esophagus. Dis Esophagus, 15:330-333, 2002
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2) Heimlich HJ:A life-saving maneuver to prevent food-choking. JAMA, 234:398-401, 1975
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3) Heimlich HJ:Update on the Heimlich maneuver. Emerg Med Serv, 6:11-13, 16-17, 19-20 passim, 1977
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4) Chillag S, et al:The Heimlich maneuver:breaking down the complications. South Med J, 103:147-150, 2010
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32 テレビゲームが疾患を生む ?

P.69 掲載の参考文献
1) Bonis J:Acute Wiiitis. N Engl J Med, 356:2431-2432, 2007
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2) Brodmann M, et al:Acute wiiitis representing as thrombosis of the inferior vena cava and left pelvic veins. Phlebology, 30:486-488, 2015
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3) Brasington R:Nintendinitis. N Engl J Med, 322:1473-1474, 1990
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4) Jalink MB, et al:Nintendo related injuries and other problems:review. BMJ, 349:g7267, 2014
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5) Corkery JC:Nintendo power. Am J Dis Child, 144:959, 1990
 

33 「目散る」アルコール

P.71 掲載の参考文献
1) Becker CE:Methanol poisoning. J Emerg Med, 1:51-58, 1983
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34 心臓の穴は片頭痛を起こす ?

P.73 掲載の参考文献
1) Lip PZ & Lip GY:Patent foramen ovale and migraine attacks:a systematic review. Am J Med 127:411-420, 2014
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2) Wilmshurst PT:The role of persistent foramen ovale and other shunts in decompression illness. Diving Hyperb Med, 45:98-104, 2015
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3) Dowson A, et al:Migraine Intervention With STARFlex Technology (MIST) trial:a prospective, multicenter, double-blind, sham-controlled trial to evaluate the effectiveness of patent foramen ovale closure with STARFlex septal repair implant to resolve refractory migraine headache. Circulation, 117:1397-1404, 2008
 

35 氷をバリバリかじる人は病気 ?

P.75 掲載の参考文献
1) Rector WG Jr:Pica:its frequency and significance in patients with iron-deficiency anemia due to chronic gastrointestinal blood loss. J Gen Intern Med, 4:512-513, 1989
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2) Hunt MG, et al:Pagophagia improves neuropsychological processing speed in iron-deficiency anemia. Med Hypotheses, 83:473-476, 2014
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3) Woods SC & Weisinger RS:Pagophagia in the albino rat. Science, 169:1334-1336, 1970
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4) Berger K, et al:Iron metabolism and the risk of restless legs syndrome in an elderly general population--the MEMO-Study. J Neurol, 249:1195-1199, 2002
 

36 バンジージャンプで失明 ?

P.77 掲載の参考文献
1) Hassan HM, et al:Ocular complications of bungee jumping. Clin Ophthalmol, 6:1619-1622, 2012
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2) Habib NE & Malik TY:Visual loss from bungee jumping. Lancet, 343:487, 1994
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3) Michaels L, et al:Postcoital visual loss due to valsalva retinopathy. BMJ Case Rep:2014, 2014
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37 マリンスポーツと納豆アレルギーの意外な関係

P.79 掲載の参考文献
1) Suzuki S, et al:A case of "late-onset" anaphylaxis caused by fermented soybeans;natto. Arerugi, 55:832-836, 2006
 
2) Inomata N, et al:Anaphylaxis caused by ingesting jellyfish in a subject with fermented soybean allergy:Possibility of epicutaneous sensitization to poly-gamma-glutamic acid by jellyfish stings. J Dermatol, 41:752-753, 2014
 
3) 猪又直子:納豆アレルギー. M B Derma, 229:49-55, 2015
 

38 医者はどこへ行くのか ?

P.81 掲載の参考文献
1) 平成26年(2014年)医師・歯科医師・薬剤師調査の概況. 厚生労働省, 2015 http://www.mhlw.go.jp/toukei/saikin/hw/ishi/14/dl/toukeihyo.pdf
 
2) Myhre DL, et al:Determinants of an urban origin student choosing rural practice:a scoping review. Rural Remote Health, 15:3483, 2015
 
3) Holmes JE & Miller DA:Factors affecting decisions on practice locations. J Med Educ, 61:721-726, 1986
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39 ゴッホの絵が黄色っぽい理由

P.83 掲載の参考文献
1) Madreperla SA, et al:Electrophysiologic and electroretinographic evidence for photoreceptor dysfunction as a toxic effect of digoxin. Arch Ophthalmol, 112:807-812, 1994
PubMed
2) Arnold WN & Loftus LS:Xanthopsia and van Gogh's yellow palette. Eye (Lond), 5(Pt 5):503-510, 1991
 

40 ヘリウムガスを使った宴会芸に注意

P.85 掲載の参考文献
1) Howard MO, et al:Suicide by asphyxiation due to helium inhalation. Am J Forensic Med Pathol, 32:61-70, 2011
PubMed
2) Ogden RD, et al:Assisted suicide by oxygen deprivation with helium at a swiss right-to-die organisation. J Med Ethics, 36:174-179, 2010
 
3) Auwaerter V, et al:Toxicological analysis after asphyxial suicide with helium and a plastic bag. Forensic Sci Int, 170:139-141, 2007
 
4) Oosting R, et al:Toxicological findings in three cases of suicidal asphyxiation with helium. Forensic Sci Int, 256:38-41, 2015
PubMed

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