腫瘍病理鑑別診断アトラス　十二指腸・小腸・虫垂腫瘍

出版社： 文光堂
著者：
発行日： 2021-04-14
分野： 臨床医学：基礎  >  臨床病理学
ISBN： 9784830622571
シリーズ： 腫瘍病理鑑別診断アトラス
電子書籍版： 2021-04-14 （第1版第1刷）
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近年の内視鏡検診の普及，またカプセル内視鏡やダブルバルーン内視鏡の普及に伴い，十二指腸や小腸，虫垂領域では，小病変を含め様々な疾患の発見機会が増えている．しかしこの領域には「規約」や「ガイドライン」がなく，WHO分類第5版でも診断に十分な記載があるとも言い難い．本書は，最新の知見を盛り込み，日本における標準的な組織分類や診断基準などを提示し，この領域の病理診断のゴールドスタンダードをめざす．また，典型例から希少例まで多数の組織像を掲載し，「十二指腸・小腸・虫垂」領域の病理を一望できる．すべての病理医必読の1冊．

目次

  • 第1部　検鏡前の確認事項
    　I．十二指腸・小腸腫瘍の組織分類
    　　1．小腸粘膜・異所性胃型上皮
    　　2．十二指腸・小腸腺腫の組織分類と粘膜内癌
    　　3．腸型腺腫・幽門腺腺腫
    　　4．腸型腺腫・幽門腺腺腫に分類できない非浸潤性病変および良悪境界病変
    　　5．腺　癌
    　II．虫垂腫瘍の組織分類
    　　1．WHO分類と大腸癌取扱い規約の概要
    　　2．WHO分類，癌取扱い規約分類の比較・相違点
    　III．切除標本の取扱い方
    　　1．一般的事項
    　　2．外科切除標本の取扱い
    　　3．内視鏡切除標本の取扱い
    　IV．肉眼診断
    　　1．十二指腸を含む小腸原発癌の肉眼型・肉眼所見
    　　2．虫垂癌・虫垂腫瘍の肉眼所見

    第2部　組織型と診断の実際
    　I．十二指腸上皮性腫瘍
    　　1．腺腫と境界病変
    　　2．腺　癌
    　　3．稀な組織型の癌
    　　　1．粘液癌
    　　　2．印環細胞癌
    　　　3．腺扁平上皮癌・扁平上皮癌
    　　　4．肝様腺癌・胎児消化管上皮類似癌
    　　　5．癌肉腫
    　II．小腸（空腸・回腸）上皮性腫瘍
    　　1．小腸の上皮性良性腫瘍
    　　2．腺　癌
    　III．虫垂上皮性腫瘍
    　　1．腺　腫
    　　2．低異型度虫垂粘液性腫瘍
    　　3．鋸歯状病変
    　　4．腺　癌
    　　5．杯細胞腺癌（杯細胞型カルチノイド）
    　IV．内分泌細胞腫瘍
    　　1．日本分類における消化管内分泌細胞腫瘍の概念
    　　2．内分泌細胞腫瘍の分類
    　　3．カルチノイド腫瘍
    　　4．内分泌細胞癌
    　　5．内分泌細胞腫瘍の病理診断の手順と項目
    　　6．内分泌細胞腫瘍の組織学的な鑑別診断
    　V．間葉系腫瘍
    　　1．GIST
    　　2．GIST以外の間葉系腫瘍
    　　　1．平滑筋腫
    　　　2．平滑筋肉腫
    　　　3．デスモイド型線維腫症
    　　　4．炎症性筋線維芽細胞腫瘍
    　　　5．炎症性線維性ポリープ
    　　　6．孤立性線維性腫瘍
    　　　7．脱分化型脂肪肉腫
    　　　8．消化管明細胞肉腫/悪性消化管神経外胚葉性腫瘍
    　　　9．神経鞘腫
    　　　10．虫垂神経腫
    　　　11．神経節神経腫
    　　　12．gangliocytic paraganglioma
    　　　13．グロームス腫瘍
    　　　14．Kaposi肉腫
    　　　15．その他の間葉系腫瘍
    　VI．悪性リンパ腫と類似病変
    　　1．十二指腸型濾胞性リンパ腫
    　　2．単形性上皮向性腸管T 細胞リンパ腫（MEITL）と腸症関連T 細胞リンパ腫（EATL）
    　　3．その他の十二指腸・小腸・虫垂に発生する主なリンパ腫と類似病変
    　VII．転移性腫瘍
    　VIII．ポリポーシス・遺伝性疾患
    　　1．Peutz-Jeghers症候群
    　　2．家族性大腸腺腫
    　　3．若年性ポリポーシス
    　　4．Cowden病/PTEN過誤腫症候群
    　　5．Cronkhite-Canada症候群
    　　6．Lynch症候群
    　IX．Crohn病関連腫瘍
    　X．腫瘍様病変
    　　1．定義・概念
    　　2．正常構築
    　　3．胃型・Brunner腺型病変
    　　4．Peutz-Jeghers型ポリープ
    　　5．異所性膵とadenomyoma/myoepithelial hamartoma
    　　6．子宮内膜症
    　　7．炎症性ポリープ・ポリポーシス
    　　8．間葉系の腫瘍様病変

    第3部　鑑別ポイント
    　I．十二指腸腺腫と癌の診断基準
    　　1．腺腫と癌の病理組織学的診断基準
    　　2．病理組織学的鑑別診断の実際
    　　3．鑑別診断に有用な臨床的事項
    　II．虫垂粘液性腫瘍の鑑別診断
    　　1．鑑別すべき疾患
    　　2．虫垂粘液性腫瘍
    　　3．粘液癌
    　　4．良性病変
    　III．反応性異型と腫瘍性異型との鑑別診断
    　　1．十二指腸粘膜に関する基礎的事項
    　　2．表層上皮の反応性異型と腫瘍性異型との鑑別
    　　3．Brunner腺の反応性異型と腫瘍性異型との鑑別

    第4部　臨床との連携
    　I．コンパニオン診断
    　　1．免疫チェックポイント阻害薬のコンパニオン診断
    　　2．MSI/dMMR/TMB検査法
    　　3．MSI-H/dMMRを示す癌の特徴
    　　4．NTRK 融合遺伝子
    　　5．分子標的治療の現状
    　II．内視鏡所見
    　　1．十二指腸腫瘍の内視鏡診断
    　　2．小腸腫瘍の内視鏡診断
    　　3．虫垂腫瘍の内視鏡診断
    　　4．病理医と臨床医の連携─正確な診断のための確認事項
    　III．腹腔細胞診の判定と臨床的意義
    　　1．腹腔細胞診の目的と臨床診療における位置づけ
    　　2．実施方法
    　　3．スクリーニングと判定の手順
    　　4．判定結果の記載方法
    　　5．腹腔細胞診観察のポイント
    　　6．腹腔細胞診の腫瘍細胞像
    　　7．鑑別の必要な非腫瘍性細胞
    　IV．治療ガイドラインの概要
    　　1．腺腫・癌
    　　2．NETとNEC
    　　3．GIST
    　　4．悪性リンパ腫
    　V．病理診断報告書の記載
    　　1．手術検体における病理報告の記載
    　　2．内視鏡的切除検体の病理所見の記載
    　　3．悪性リンパ腫，GISTの病理所見の記載
    　　4．生検検体の病理所見の記載

この書籍の参考文献

参考文献のリンクは、リンク先の都合等により正しく表示されない場合がありますので、あらかじめご了承下さい。

本参考文献は電子書籍掲載内容を元にしております。

第1部 検鏡前の確認事項

P.8 掲載の参考文献
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PubMed
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1) 大腸癌研究会 (編) : 大腸癌取扱い規約, 第9版, 金原出版, 2018, 67-71
 
2) 味岡洋一 : 小腸・虫垂・大腸・肛門. 病理と臨床 2008, 26 (臨増) : 154-159
 
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2) Schottenfeld D, Beebe-Dimmer JL, Vigneau FD : The epidemiology and pathogenesis of neoplasia in the small intestine. Ann Epidemiol 2009, 19 : 58-69
 
3) 日本胃癌学会 (編) : 胃癌取扱い規約, 第15版, 金原出版, 2017
 
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16) 三澤俊一, 堀江久永, 熊野秀俊ほか : 当院での原発性小腸癌10例の臨床病理学的検討と最近5年間の本邦報告例116例の文献的考察. 日消誌 2011, 108 : 429-435
 
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第2部 組織型と診断の実際

P.41 掲載の参考文献
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第3部 鑑別ポイント

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第4部 臨床との連携

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