麻酔科医のための体外循環の知識

出版社： 克誠堂出版
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発行日： 2022-11-15
分野： 臨床医学：外科  >  麻酔科学/ペイン
ISBN： 9784771905719
電子書籍版： 2022-11-15 （第1版第1刷）
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経食道心エコーが急速な普及を果たし、今や必要不可欠な術中モニターとなりましたが、心臓血管麻酔領域で次にわれわれが取り組むべき重要課題は体外循環（人工心肺）であることは疑う余地がありません。
専門医取得を目指している麻酔科医をターゲットとしていますが、若手医師にも理解しやすい内容としています。複雑な内容は敢えて割愛し、基本的な内容を中心に心臓血管外科手術の周術期管理に必要な内容に特化しています。

目次

  • 第1章　体外循環の歴史
    第2章　人工心肺装置
    第3章　血液ポンプ
    第4章　人工肺
    第5章　人工心肺操作の実際
    第6章　人工心肺中のモニタリング
    第7章　人工心肺中の麻酔管理
    第8章　心筋保護
    第9章　人工心肺中の抗凝固療法
    第10章　体外循環中の適切な灌流圧と血液希釈
    第11章　人工心肺中の体温管理
    第12章　人工心肺中の生体反応
    第13章　大動脈手術の人工心肺
    第14章　小児の人工心肺
    第15章　低侵襲手術のための人工心肺
    第16章　非心臓手術への適応
    第17章　補助循環と人工心臓
    第18章　経皮的心肺補助(PCPS)と体外式膜型人工肺(ECMO)
    第19章　血液浄化療法
    第20章　安全管理とトラブルシューティング

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参考文献のリンクは、リンク先の都合等により正しく表示されない場合がありますので、あらかじめご了承下さい。

本参考文献は電子書籍掲載内容を元にしております。

第1章 体外循環の歴史

P.8 掲載の参考文献
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第2章 人工心肺装置

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第3章 血液ポンプ

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第4章 人工肺

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第5章 人工心肺操作の実際

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第6章 人工心肺中のモニタリング

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第7章 人工心肺中の麻酔管理

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第8章 心筋保護

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第9章 人工心肺中の抗凝固療法

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第10章 体外循環中の適切な灌流圧と血液希釈

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3) Nakajima Y, Baudry N, Duranteau J, et al. Microcirculation in intestinal villi:a comparison between hemorrhagic and endotoxin shock. Am J Respir Crit Care Med 2001;164(8 Pt 1):1526-30.
 
4) Reistima S, Slaaf DW, Vink H, et al. The endothelial glycocalyx:composition, functions, and visualization. Eur J Physiol 2007;454:345-59.
 
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6) Oberleithner H, Wilhelmi M. Determination of erythrocyte sodium sensitivity in man. Pflugers Arch 2013;465:1459-66.
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14) Bruegger D, Jacob M, Rehm M, et al. Atrial natriuretic peptide induces shedding of endothelial glycocalyx in coronary vascular bed of guinea pig hearts. Am J Physiol Heart Circ Physiol 2005;289:1993-9.
 
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18) Boston US, Slater JM, Orszulak TA, et al. Hierarchy of regional oxygen delivery during cardiopulmonary bypass. Ann Thorac Surg 2001;71:260-4.
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第11章 人工心肺中の体温管理

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第12章 人工心肺中の生体反応

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39) Caso G, Vosswinkel JA, Garlick PJ, et al. Altered protein metabolism following coronary artery bypass graft (CABG)surgery. Clin Sci 2008;114:339-46.
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40) Corbett SA. Systemic Response to Injury and Metabolic Support. In:Brunicardi FC, Andersen DK, Billiar TR, Dunn DL, Kao LS, Hunter JG, Matthews JB, Pollock RE, eds. Schwartz's Principle of Surgery. 11th ed. McGraw Hill;2019. https://accessmedicine.mhmedical.com/content.aspx?bookid=2576&sectionid=210405073(2022年5月14日閲覧)
 

第13章 大動脈手術の人工心肺

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1) Erbel R, Aboyans V, Boileau C, et al. 2014 ESC Guidelines on the diagnosis and treatment of aortic diseases:Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology(ESC). Eur heart J 2014;35:2873-926.
 
2) Xia Q, Cao Y, Xie B, et al. Cannulation strategies in type A aortic dissection:a novel insight narrative review. J Thorac Dis 2021;13:2551-62.
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3) 宮入 剛, 木川 幾, 三浦 友. 急性大動脈解離手術におけるswitching対策-マルチモニタリングと右上腕動脈送血の意義. 胸部外科2007;60:319-23.
 
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5) Qu JZ, Kao LW, Smith JE, et al. Brain protection in aortic arch surgery:an evolving field. J Cardiothorac Vasc Anesth 2021;35:1176-88.
 
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7) Halstead JC, Wurm M, Meier DM, et al. Avoidance of hemodilution during selective cerebral perfusion enhances neurobehavioral outcome in a survival porcine model. Eur J Cardiothorac Surg 2007;32:514-20.
 
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10) De Paulis R, Czerny M, Weltert L, et al. Current trends in cannulation and neuroprotection during surgery of the aortic arch in Europe. Eur J Cardiothorac Surg 2015;47:917-23.
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11) Tian DH, Wan B, Bannon PG, et al. A meta-analysis of deep hypothermic circulatory arrest versus moderate hypothermic circulatory arrest with selective antegrade cerebral perfusion. Ann Cardiothorac surg 2013;2:148-58.
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13) Tian DH, Wilson-Smith A, Koo SK, et al. Unilateral versus bilateral antegrade cerebral perfusion:a meta-analysis of comparative studies. Heart Lung Circ 2019;28:844-9.
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14) Papantchev V, Stoinova V, Aleksandrov A, et al. The role of Willis circle variations during unilateral selective cerebral perfusion:a study of 500 circles. Eur J Cardiothorac Surg 2013;44:743-53.
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15) Leshnower BG, Rangaraju S, Allen JW, et al. Deep hypothermia with retrograde cerebral perfusion versus moderate hypothermia with antegrade cerebral perfusion for arch surgery. Ann Thorac Surg 2019;107:1104-10.
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16) Guo S, Sun Y, Ji B, et al. Similar cerebral protective effectiveness of antegrade and retrograde cerebral perfusion during deep hypothermic circulatory arrest in aortic surgery:a meta-analysis of 7023 patients. Artif Organs 2015;39:300-8.
 
17) Okita Y, Miyata H, Motomura N, et al. A study of brain protection during total arch replacement comparing antegrade cerebral perfusion versus hypothermic circulatory arrest, with or without retrograde cerebral perfusion:analysis based on the Japan Adult Cardiovascular Surgery Database. J Thorac Cardiovasc Surg 2015;149:S65-73.
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18) Hameed I, Rahouma M, Khan FM, et al. Cerebral protection strategies in aortic arch surgery:a network meta-analysis. J Thorac Cardiovasc Surg 2019;S0022-5223(19)30483-0.
 

第14章 小児の人工心肺

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2) 横川忠一, 阿部正一, 阿部弥之, ほか. 小児開心術における無輸血体外循環. 体外循環技術2003;30:26-8.
 
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5) 宮本和幸, 米永國宏, 平山統一, ほか. 小児開心術におけるmodified ultrafiltration の有用性 無輸血症例と輸血施行症例についての検討. 日心外会誌2001;30:290-4.
 
6) 野村卓哉, 布村仁亮, 戸畑裕志, ほか. 人工心肺回路熱交換器を用いた小児開心術時のmodified ultrafiltration 実施に伴う体温低下防止. 体外循環技術2014;41:148-52.
 
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第15章 低侵襲手術のための人工心肺

P.157 掲載の参考文献
1) 平林則行. 低侵襲手術(MICS)での人工心肺. 四津良平. CE技術シリーズ-人工心肺-. 東京:南江堂;2015. p.159-70.
 
2) 百瀬直樹. 人工心肺装置. 山口敦司. 人工心肺ハンドブック(改訂第3版). 東京:中外医学社;2020. p.62-108.
 
3) 日本心臓血管外科学会, 日本胸部外科学会, 日本人工臓器学会. 3学会合同陰圧吸引補助脱血体外循環検討委員会報告並びに勧告. https://plaza.umin.ac.jp/~jscvs/negative-pressure/(2022年4月12日閲覧)
 
4) Hosono M, Yasumoto H, Kuwauchi S, et. al. Utility of Ultrasonographic Assessment of Distal Femoral Arterial Flow during Minimally Invasive Valve Surgery. Ann Thorac Cardiovasc Surg. 2021;27:389-94.
 
5) Toya T, Fujita T, Fukushima S, et al. Efficacy of regional saturation of oxygen monitor using near-infrared spectroscopy for lower limb ischemia during minimally invasive cardiac surgery. J Artif Organs 2018;21:420-6.
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6) Inoue K, Hiraoka A, Chikazawa G, et al. Preventive Strategy for Reexpansion Pulmonary Edema After Minimally Invasive Cardiac Surgery. The Ann Thorac Surg 2020;109:375-7.
 

第16章 非心臓手術への適応

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3) Ried M, Bein T, Philipp A, et al. Extracorporeal lung support in trauma patients with severe chest injury and acute lung failure:a 10-year institutional experience. Crit Care 2013;17:R110.
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4) Lee JG, Kim N, Narm KS, et al. The Effect of additional stepwise venous inflow on differential hypoxia of veno-arterial extracorporeal membrane oxygenation. ASAIO J 2020;66:803-8.
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6) Calderone CE, Tuck BC, Gray SH, et al. The role of transesophageal echocardiography in the management of renal cell carcinoma with venous tumor thrombus. Echocardiography 2018;35:2047-55.
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7) 北村俊治, 土居久栄, 沼田克雄. 体外循環使用による気管狭窄症の麻酔. 麻酔1988;37:81-5.
 
8) 山口恭子, 藤本啓子, 小出康弘, ほか. 甲状腺癌による高度気管狭窄患者の気道管理 V-V ECMOとHFJV併用の有用性. 麻酔2013;62:78-82.
 
9) Kim DH, Park JM, Son J, et al. Multivariate analysis of risk factor for mortality and feasibility of extracorporeal membrane oxygenation in high-risk thoracic surgery. Ann Thorac Cardiovasc Surg 2021;27:97-104.
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10) Sawadogo A, D'Ostrevy N, Belem FP, et al. Extracorporeal life support as a lifesaving procedure in palliative surgery of stenosing upper tracheal tumor. Ann Card Anaesth 2021;24:389-91.
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11) Kodia K, Liu Y, Ghodsizad A, et al. Use of venovenous extracorporeal membrane oxygenation for resection of a large paratracheal mass causing critical tracheal stenosis:a case report. J Card Surg 2021;36:367-70.
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12) Kim SH, Song S, Kim YD, et al. Outcomes of extracorporeal life support during surgery for the critical airway stenosis. ASAIO J 2017;63:99-103.
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13) 児嶋 剛, 安里 亮, 池田晴人, ほか. 体外循環補助下に挿管した縦隔甲状腺腫瘍例. 耳鼻臨床2004;97:621-5.
 
14) Diamond JM, Lee JC, Kawut SM, et al. Clinical risk factors for primary graft dysfunction after lung transplantation. Am J Respir Crit Care Med 2013;187:527-34.
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15) 五藤恵次. 肺移植の麻酔. 麻酔2014;63:S1-S7.
 
16) 濱井優輔, 石坪昌恵, 濱田美帆, ほか. 脳死肺移植手術中の緊急体外循環使用に関与する因子の検討. 麻酔2017;66:1281-6.
 
17) Subramaniam K, Rio JMD, Wilkey BJ, et al. Anesthetic management of lung transplantation:results from a multicenter, cross-sectional survey by the society for advancement of transplant anesthesia. Clin Transplant 2020;34:e13996.
 
18) Magouliotis DE, Tasiopoulou VS, Svokos AA, et al. Extracorporeal membrane oxygenation versus cardiopulmonary bypass during lung transplantation:a meta-analysis. Gen Thorac Cardiovasc Surg 2018;66:38-47.
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19) Ohsumi A, Date H. Perioperative circulatory support for lung transplantation. Gen Thorac Cardiovasc Surg 2021;69:631-7.
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20) Ruszel N, Kielbowski K, Piotrowska M, et al. Central, peripheral ECMO or CPB? Comparsion between circulatory support methods used during lung transplantation. J Cardiothorac Surg 2021;16:341.
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21) Yeo HJ, Kim DH, Jeon D, et al. Low-dose heparin during extracorporeal membrane oxygenation treatment in adults. Intensive Care Med 2015;41:2020-1.
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22) Scaravilli V, Fumagalli J, Rosso L, et al. Heparin-free lung transplantation on venovenous extracorporeal membrane oxygenation bridge. ASAIO J 2021;67:e191-e7.
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23) Chari RS, Gan TJ, Robertson KM, et al. Venovenous bypass in adult orthotopic liver transplantation:routine or selective use? J Am Coll Surg 1998;186:683-90.
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24) Hoffmann K, Weigand MA, Hillebrand N, et al. Is veno-venous bypass still needed during liver transplantation? A review of the literature. Clin Transplant 2009;23:1-8.
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25) Barbas AS, Levy J, Mulvihill MS, et al. Liver transplantation without venovenous bypass:does surgical approach matter? Transplant Direct 2018;4:e348.
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26) Gravlee GP, Davis RF, Stammers AH, et al. 人工心肺:その原理と実際:メディカル・サイエンス・インターナショナル;2010.
 
27) Sun K, Hong F, Wang Y, et al. Venovenous bypass is associated with a lower incidence of acute kidney injury after liver transplantation in patients with compromised pretransplant renal function. Anesth Analg 2017;125:1463-70.
 
28) Lapisatepun W, Lapisatepun W, Agopian V, et al. Venovenous bypass during liver transplantation:a new look at an old technique. Transplant Proc 2020;52:905-9.
 
29) Van Hoof L, Rega F, Devroe S, et al. Successful resuscitation after hyperkalemic cardiac arrest during liver transplantation by converting veno-venous bypass to veno-arterial ECMO. Perfusion 2021;36:766-8.
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31) 下村 啓, 三宅聰行, 新井豊久, ほか. 開胸式体外循環を併用し, 低体温下に脳底動脈瘤のクリッピングが行われた2症例. 日臨麻誌1996;16:716-21.
 
32) 佐藤 章, 中村 弘, 小林繁樹, ほか. 【脳動脈瘤の新しい治療戦略】脳動脈瘤手術における低体温麻酔の使用はどのように有効か. 脳卒中の外科1999;27:183-8.
 

第17章 補助循環と人工心臓

P.180 掲載の参考文献
1) 川人宏次. 第13章 補助循環. 井野隆史, 安達秀雄, 編. 最新体外循環 基本的知識と安全の確保. 東京:金原出版;2003. p.265-76.
 
2) 日本循環器学会/日本心不全学会合同ガイドライン. 2021年JCS/JHFSガイドライン フォーカスアップデート版 急性・慢性心不全診療. https://www.j-circ.or.jp/cms/wp-content/uploads/2021/03/JCS2021_Tsutsui.pdf(2022年3月9日閲覧)
 
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4) 日本循環器学会/日本心臓血管外科学会/日本胸部外科学会/日本血管外科学会合同ガイドライン:2021年改訂版 重症心不全に対する植込型補助人工心臓治療ガイドライン. https://www.j-circ.or.jp/cms/wp-content/uploads/2021/03/JCS2021_Ono_Yamaguchi.pdf(2022年3月9日閲覧)
 
5) 日本循環器学会/日本心不全学会合同ガイドライン:急性・慢性心不全診療ガイドライン(2017年改訂版). https://www.j-circ.or.jp/cms/wp-content/uploads/2017/06/JCS2017_tsutsui_h.pdf(2022年3月9日閲覧)
 

第18章 経皮的心肺補助 ( PCPS ) と体外式膜型人工肺 ( ECMO )

P.191 掲載の参考文献
1) 日本循環器学会/日本心不全学会. 2021年JCS/JHFSガイドライン フォーカスアップデート版 急性・慢性心不全診療. https://www.j-circ.or.jp/cms/wp-content/uploads/2021/03/JCS2021_Tsutsui.pdf(2022年5月3日閲覧)
 
2) Lorusso R, Shekar K, Maclaren G, et al. ELSO Interim guideline for veno-arterial extracorporeal membrane oxygenation in adult cardiac patients. ASAIO J 2021;67:827-44.
 
3) Schmidt M, Burrel A, Roberts L, et al. Predicting survival after ECMO for refractory cardiogenic shock:The survival after venoarterial-ECMO(SAVE)score. EurHeart J 2015;36:2246-56.
 
4) 日本集中治療医学会/日本呼吸療法医学会/日本呼吸器学会. ARDS診療ガイドライン2016. https://www.jsicm.org/pdf/ARDSGL2016.pdf#view=FitV(2022年5月3日閲覧)
 
5) Joseph E. Tonna, Darryl Abrams, Daniel Brodie et al. Management of adult patients supported with veno-venous extracorporeal membrane oxygenation(VV ECMO):guideline from the Extracorporeal life support organization. ASAIO J 2021;67:601-10.
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第19章 血液浄化療法

P.204 掲載の参考文献
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3) Yasuda H, Uchino S, Uji M, et al. Japanese Society for Physicians and Trainees in Intensive Care(JSEPTIC) Clinical Trial Group. The lower limit of intensity to control uremia during continuous renal replacement therapy. Crit Care 2014;18:539.
 
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5) Zarbock A, Kellum JA, Schmidt C, et al. Effect of early vs delayed initiation of renal replacement therapy on mortality in critically ill patients with acute kidney injury:The ELAIN randomized clinical trial. JAMA 2016;315:2190-9.
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第20章 安全管理とトラブルシューティング

P.216 掲載の参考文献
1) 日本体外循環技術医学会安全対策委員会, 教育委員会. 人工心肺における安全装置の設置に関する勧告 改訂6版. 体外循環技術2021;48(2):巻頭.
 
2) 日本体外循環技術医学会. 人工心肺ならび補助循環に関するインシデント・アクシデントおよび安全に関するアンケート2019の結果報告. 体外循環技術2022;49:42-71.
 
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5) 日本体外循環技術医学会安全対策委員会. 人工心肺における安全装置設置状況に関するアンケート2016. 体外循環技術2017;44:355-65.
 
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