5) Yamazaki S, Muta T, Takeshige K : A novel IκB protein, 1κB-ζ, induced by proinflammatory stimuli, negatively regulates nuclear factor-κB in the nuclei. J Biol Chem 276 : 27657-27662, 2001
6) Kitamura H, Kanehira K, Okita K, et al. : MAIL, a novel nuclear IκB protein that potentiates LPS-induced IL-6 production. FEBS Lett 485 : 53-56, 2000
9) Fiorini E, Schmitz I, Marissen WE, et al. : Peptide-induced negative selection of thymocytes activates transcription of an NF-κB inhibitor. Mol Cell 9 : 637-648, 2002
11) Motoyama M, Yamazaki S, Eto-Kimura A, et al. : Positive and negative regulation of nuclear factor-κB-mediated transcription by IκB-ζ, an inducible nuclear protein. J Biol Chem 280 : 7444-7451, 2005
12) Yamazaki S, Muta T, Matsuo S, et al. : Stimulus-specific induction of a novel nuclear fac tor-κB regulator, IκB-ζ, via Toll/Interleukin-1 receptor is mediated by mRNA stabilization. J Biol Chem 280 : 1678-1687, 2005
13) Yamamoto M, Yamazaki S, Uematsu S, et al, : Regulation of Toll/IL-1-receptormediated gene expression by the inducible nuclear protein IκBζ. Nature 430 : 218-222, 2004
14) Wulczyn FG, Naumann M, Scheidereit C : Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-κB. Nature 358 : 597-599, 1992
15) Hirotani T, Lee PY, Kuwata H, et al. : The nuclear IκB protein IκBNS selectively inhibits lipopolysaccharide-induced IL-6 production in macrophages of the colonic lamina propria. J Immunol 174 : 3650-3657, 2005
16) Shiina T, Konno A, Oonuma T, et al. : Targeted disruption of MAIL, a nuclear IκB protein, leads to severe atopic dermatitis-like disease. J Biol Chem 279 : 55493-55498, 2004
17) Ueta M, Hamuro J, Yamamoto M, et al. : Spontaneous ocular surface inflammation and goblet cell disappearance in IκBζ genedisrupted mice. Invest Ophthalmol Vis Sci 46 : 579-588, 2005
18) Kuwata H, Matsumoto M, Atarashi K, et al. : IκBNS inhibits induction of a subset of Toll-like receptor-dependent genes and limits inflammation. Immunity 24 : 41-51, 2006
19) Eto A, Muta T, Yamazaki S, et al. : Essential roles for NF-κB and a Toll/IL-1 receptor domain-specific signal (s) in the induction of IκB一ζ. Biochem Biophys Res Commun 301 : 495-501, 2003
21) Ninomiya-Tsuji J, Kishimoto K, Hiyama A, et al. : The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature 398 : 252-256, 1999
23) Irie T, Muta T, Takeshige K : TAK1 mediates an activation signal from toll-like receptor (s) to nuclear factor-κB in lipopolysaccharide-stimulated macrophages. FEBS Lett 467 : 160-164, 2000