悪性リンパ腫 臨床と病理 ―WHO分類(第4版)に基づいて―

出版社： 先端医学社
著者：
発行日： 2009-12-01
分野： 臨床医学：一般  >  癌/腫瘍一般
ISBN： 9784884075958
電子書籍版： 2009-12-01 （第1第1刷）
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ＷＨＯ分類第4版―悪性リンパ腫診断・治療　最新の集大成―
悪性リンパ腫分類の国際標準WHO分類改訂第4版が2008年9月公表された。本書はその日本語版であるが、ただの病型分類の羅列にとどまらず、本分類が実臨床で果たす意義をわが国を代表するエキスパートが詳細に示した実践書である。【総論】ではＷＨＯ分類の概説と診断・治療の基本事項とトピックスを、【各論】の<病理><臨床>各項では、ＷＨＯ分類を理解し活かす治療法を解説。主な病型には<まとめ>の項が付され、見開きで基本事項が把握可能である。リンパ腫に付随する造詣を深められる<コラム>も随所に登場。血液専門医、病理医、それを目指して研修中の医師をはじめ悪性リンパ腫に接する機会のある各科の医療関係者必携の集大成。

目次

  • 表紙
  • B細胞腫瘍,T / NK細胞腫瘍,およびHodgkinリンパ腫のWHO分類（第4版）
  • 改定序
  • 初版序
  • 執筆者一覧
  • 目次
  • 総論
  • 1. WHO分類が目指すもの
  • 2. WHO分類（第4版）の概要とおもな改訂点
  • 3. 免疫表現型（免疫染色,FCM）
  • 3-(1) 単クローン性抗体とノーベル賞
  • 3-(2) ヒト白血球分化抗原 / ヒト細胞分化分子
  • 3-(3) Rituximab
  • 4. 染色体・遺伝子異常と検査結果の解釈
  • 5. 悪性リンパ腫の予後因子および予後予測
  • 5 nm23について
  • 6. 悪性リンパ腫の病型頻度
  • 6-(1) 芽球とリンパ球
  • 6-(2) リンパ腫分類と皮膚リンパ腫
  • 7. 診断と治療のトピックス
  • 1) リンパ腫に対する新薬開発
  • 2） 悪性リンパ腫におけるPET / CTの有用性
  • 7-2) Standardized uptake value
  • 3） 90Y-lbritumomab tiuxetan（Zevalin）
  • 各論
  • Part I◆B細胞腫瘍
  • 1-0. B細胞腫瘍アウトライン
  • 1-1. Bリンパ芽球性白血病 / リンパ腫 <臨床と病理>
  • I 1-1-(1) Bリンパ芽球性リンパ腫で用いられる用語
  • I 1-1-(2) Tリンパ芽球性リンパ腫およびBリンパ芽球性リンパ腫の病理と臨床病態
  • 2-0. 濾胞性リンパ腫 <まとめ>
  • 2-1. 濾胞性リンパ腫 解説 <病理>
  • 2-2. 濾胞性リンパ腫 解説 <臨床>
  • I 2-2-(1) t(14;18)(q32;q21)型濾胞性リンパ腫とt(3;14)(q27;q32)型濾胞性リンパ腫
  • I 2-2-(2) 濾胞性リンパ腫のrituximab維持療法に関する知見
  • I 2-2-(3) 濾胞性リンパ腫のgrade進展,組織学的進展と+der（18）t（14;18）
  • 2-3. 腸管原発濾胞性リンパ腫 <臨床と病理>
  • 3-0. マントル細胞リンパ腫 <まとめ>
  • 3-1. マントル細胞リンパ腫 解説 <病理>
  • I 3-1-(1) マントル細胞リンパ腫の歴史
  • I 3-1-(2) CD5分子からみたリンパ腫
  • 3-2. マントル細胞リンパ腫 解説 <臨床>
  • I 3-2 マントル細胞リンパ腫と中枢神経系浸潤
  • 4-0. 節性濾胞辺縁帯リンパ腫 <まとめ>
  • 4-1. 節性濾胞辺縁帯リンパ腫 解説 <病理>
  • I 4-1-(1) リンパ腫と対応する正常細胞
  • I 4-1-(2) 濾胞辺縁帯リンパ腫の対応する正常細胞
  • 4-2. 節性濾胞辺縁帯リンパ腫 解説 <臨床>
  • I 4-2-(1) 小児節性濾胞辺縁帯リンパ腫
  • I 4-2-(2) 脾濾胞辺縁帯リンパ腫の治療
  • 4-3. 脾濾胞辺縁帯リンパ腫 <臨床と病理>
  • I 4-3-(1) 脾の系統発生
  • I 4-3-(2) 脾のリンパ腫分類
  • 5-0. びまん性大細胞型B細胞リンパ腫,非特異群 <まとめ>
  • 5-1. びまん性大細胞型B細胞リンパ腫,非特異群 解説 <病理>
  • 5-2. びまん性大細胞型B細胞リンパ腫,非特異群 解説 <臨床>
  • 5-3. 中・高齢者にみられるEBV陽性びまん性大細胞型B細胞リンパ腫（加齢性EBV関連B細胞リンパ増殖性疾患） <臨床と病理>A62
  • 5-4. 血管内大細胞型B細胞リンパ腫 <臨床と病理>
  • 5-5. 縦隔（胸腺）原発大細胞型B細胞リンパ腫 <臨床と病理>
  • I 5-5 縦隔(胸腺)原発大細胞型B細胞リンパ腫の治療戦略
  • 5-6. 中枢神経系原発びまん性大細胞型B細胞リンパ腫 <臨床と病理>
  • I 5-6-(1) 悪性リンパ腫の二次性中枢神経浸潤
  • I 5-6-(2) 中枢神経系原発びまん性大細胞型B細胞リンパ腫の治療方針
  • I 5-6-(3) 治療関連神経毒性
  • 5-7. ALK陽性大細胞型B細胞リンパ腫 <臨床と病理>
  • I 5-7 Anapiastic lymphoma kinase陽性大細胞型B細胞リンパ腫の鑑別のポイント
  • 5-8. 慢性炎症を伴ったびまん性大細胞型B細胞リンパ腫 <臨床と病理>
  • 5-9. CD5陽性びまん性大細胞型B細胞リンパ腫 <臨床と病理>
  • I 5-9 CD5陽性びまん性大細胞型B細胞リンパ腫に特徴的な病態
  • 5-10. その他のびまん性大細胞型B細胞リンパ腫 <臨床と病理>
  • I 5-10-(1) びまん性大細胞型B細胞リンパ腫の細分類
  • I 5-10-(2) びまん性大細胞型B細胞リンパ腫とEBウイルス
  • I 5-10-(3) びまん性大細胞型B細胞リンパ腫亜型分類と核小体
  • 6-0. Burkittリンパ腫 <まとめ>
  • 6-1. Burkittリンパ腫 解説 <病理>
  • I 6-1 Fluorescence in situ hybridization（FISH）法でC-MYC遺伝子異常を検索するには
  • 6-2. Burkittリンパ腫 解説 <臨床>
  • I 6-2 びまん性大細胞型B細胞リンパ腫とBurkittリンパ腫との中間型の特徴をもつ分類不能B細胞リンパ腫
  • 7-0-1. 節外性B細胞リンパ腫アウトライン
  • I 7-0-1-(1) 原発性浸出液リンパ腫
  • I 7-0-1-(2) 節外性濾胞辺縁帯B細胞リンパ腫の染色体異常
  • 7-0-2. 節外性濾胞辺縁帯リンパ腫：粘膜関連リンパ組織（MALT）リンパ腫 解説 <病理>
  • I 7-0-2-(1) 濾胞辺縁帯リンパ腫とリンパ腫分類
  • I 7-0-2-(2) 節外性濾胞辺縁帯リンパ腫における染色体・遺伝子異常の解釈
  • 7-1. 消化管B細胞リンパ腫 <臨床と病理>
  • I 7-1-(1) Helicobacter pyloriの診断法
  • I 7-1-(2) 病期I期胃MALTリンパ腫の治療戦略
  • I 7-1-(3) Multiple lymphomatoid polyposisを呈するマントル細胞リンパ腫の病理組織像
  • 7-2. 甲状腺リンパ腫 <臨床と病理>
  • I 7-2 甲状腺びまん性大細胞型B細胞リンパ腫に対する手術および放射線療法
  • 7-3. 眼付属器リンパ腫 <臨床と病理>
  • I 7-3-(1) 眼付属器とは
  • I 7-3-(2) 放射線晩期障害
  • I 7-3-(3) 眼付属器IgG4関連疾患
  • 7-4. 乳腺リンパ腫 <臨床と病理>
  • 7-5. 精巣リンパ腫 <臨床と病理>
  • 7-6. 骨リンパ腫 <臨床と病理>
  • 7-7. 肺リンパ腫 <臨床と病理>
  • 7-8. 子宮・卵巣リンパ腫 <臨床と病理>
  • 7-9. 鼻腔・副鼻腔リンパ腫 <臨床と病理>
  • 8. 高齢者リンパ腫の治療 <臨床と病理>
  • Part II◆TおよびNK細胞腫瘍
  • 1-0. TおよびNK細胞腫瘍アウトライン
  • II 1-0 T / NK細胞か? NK / T細胞か?
  • 1-1. Tリンパ芽球性白血病 / リンパ腫 <臨床と病理>
  • II 1-1-(1) Tリンパ芽球性リンパ腫におけるcytarabine大量療法と中枢神経系浸潤予防
  • II 1-1-(2) 臨床医はリンパ腫を診断することはできないか?細胞表面形質と臨床病態から臨床医が推測する病理組織型
  • 2-0. 未分化大細胞型リンパ腫 <まとめ>
  • 2-1. 未分化大細胞型リンパ腫 解説 <病理>
  • 2-2. 未分化大細胞型リンパ腫 解説 <臨床>
  • II 2-2 皮膚原発未分化大細胞型リンパ腫
  • 3-0. 血管免疫芽球性T細胞リンパ腫 <まとめ>
  • 3-1. 血管免疫芽球性T細胞リンパ腫 解説 <病理>
  • 3-2. 血管免疫芽球性T細胞リンパ腫 解説 <臨床>
  • II 3-2-(1) 血管免疫芽球性T細胞リンパ腫の“歴史”
  • II 3-2-(2) 細胞表面nm23について
  • 4-0. 末梢性T細胞リンパ腫,非特異群 <まとめ>
  • 4-1. 末梢性T細胞リンパ腫,非特異群 解説 <病理>
  • 4-2. 末梢性T細胞リンパ腫,非特異群 解説 <臨床>
  • II 4-2-(1) 末梢性T細胞リンパ腫に対する新薬
  • II 4-2-(2) 高齢者再発あるいは難治性末梢性T細胞リンパ腫に対するCMD療法
  • 5-0. 節外性NK / T細胞リンパ腫,鼻型 <まとめ>
  • 5-1. 節外性NK / T細胞リンパ腫,鼻型 解説 <病理>
  • 5-2. 節外性NK / T細胞リンパ腫,鼻型 解説 <臨床>
  • 6-0. 成人T細胞白血病 / リンパ腫 <まとめ>
  • 6-1. 成人T細胞白血病 / リンパ腫 解説 <病理>
  • 6-2. 成人T細胞白血病 / リンパ腫 解説 <臨床>
  • 7-1. その他の末梢性T細胞リンパ腫 <臨床と病理>
  • Part III◆Hodgkinリンパ腫
  • 1-0. Hodgkinリンパ腫 <まとめ>
  • 1-1. Hodgkinリンパ腫 解説 <病理>
  • III 1-1 びまん性大細胞型B細胞リンパ腫と古典的Hodgkinリンパ腫との中間型の特徴をもつ分類不能B細胞リンパ腫
  • 1-2. Hodgkinリンパ腫 解説 <臨床>
  • III 1-2 Hodgkinリンパ腫治療後の長期にわたる致命的な心筋梗塞のリスク
  • Part IV◆免疫不全症関連リンパ増殖性疾患
  • 1-1. 免疫不全症関連リンパ増殖性疾患-MTX関連を中心に- <臨床と病理>
  • 1-2. 免疫不全症関連リンパ増殖性疾患-MTX関連以外- <臨床と病理>
  • IV 1-2 悪性リンパ腫診断と抗HIV抗体測定
  • 索引
  • 奥付

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総論

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各論

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