臨床医・RI技師のための脳　SPECTパーフェクトガイド

出版社： メディカ出版
著者：
発行日： 2018-04-05
分野： 臨床医学：外科  >  脳神経外科学
ISBN： 9784840464918
電子書籍版： 2018-04-05 （電子書籍版）
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一般臨床病院に広く普及しているSPECTについて、臨床で活躍する医師、RI技師の視点で作成した、現場で使える本邦初の解説書。脳血管障害、てんかん、脳腫瘍、認知症、神経変性疾患、頭部外傷、髄液循環障害、精神疾患の診断・鑑別に必須の脳SPECTについて疾患別に詳しく解説。

目次

  • 【１章 総　論】
    ◆A SPECTの仕組みと意義
    ◆B 他のモダリティ（特にMRI）との比較（脳循環）
    ◆C 他のモダリティ（特にMRI）による脳腫瘍の評価

    【２章 疾患別：SPECTの特徴と使い方】
    ◆A 脳血管障害
    （1）脳虚血総論
    （2）CEA術前後評価
    （3）CAS，PTA術前後評価
    （4）バイパス術前後評価
    （5）もやもや病
    （6）脳静脈血栓症（CVT）
    （7）硬膜動静脈瘻（dAVF）
    ◆B 認知症
    （1）アルツハイマー病（AD）
    （2）レビー小体型認知症（DLB）
    （3）血管性認知症（VaD）
    （4）運動ニューロン疾患を伴う前頭側頭型認知症（FTD-MND）
    （5）行動障害型前頭側頭型認知症（bvFTD）
    （6）進行性非流暢性失語（PNFA）
    （7）意味性認知症（SD）
    （8）軽度認知障害（MCI）
    ◆C 神経変性疾患
    （1）パーキンソン病（PD）
    （2）進行性核上性麻痺（PSP）
    （3）多系統萎縮症（MSA）
    （4）大脳皮質基底核変性症（CBD）
    （5）脊髄小脳変性症（SCD）
    （6）ハンチントン病（HD）
    ◆D 脳腫瘍
    （1）201Tl SPECT
    （2）フリーソフトウエアによる201Tl SPECTとMRIの融合画像
    （3）99mTC-MIBI SPECTの臨床的有用性
    （4）123I-IMP SPECTによる悪性リンパ腫の診断
    （5）99mTC-TF，123I-IMTなど新しいトレーサーによる脳腫瘍のSPECT診断
    ◆E てんかん
    （1）診断，術前評価，焦点の同定法
    ◆F 頭部外傷
    （1）SPECTによる頭部外傷の機能的評価-1
    （2）SPECTによる頭部外傷の機能的評価-2
    ◆G 髄液循環障害
    （1）RI cisternographyによる髄液循環の評価
    （2）核医学検査による水頭症と低髄液圧症候群の評価
    ◆H 精神疾患
    （1）統合失調症（SZ）
    （2）気分障害（大うつ病性障害，双極性障害）
    （3）自閉症スペクトラム障害（ASD）（自閉症，発達障害)

    【３章 SPECT機器・核種・ソフトウエア】
    ◆A SPECT機器　
    （1）Symbia（Siemens Healthcare）
    （2）Discovery（GE Healthcare）
    （3）GCA-9300R（Canon Medical Systems）
    ◆B 核種，Isotope（脳血流シンチグラフィ）―123I-IMP，99mTc-HMPAO，99mTc-ECD
    ◆C 解析ソフトウエア
    （1）eZIS
    （2）3D-SSP
    ◆D 解析にあたり注意すべきポイント

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1章 総論

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2章 疾患別 : SPECTの特徴と使い方

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3章 SPECT機器・核種・ソフトウエア

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2) Matsuda H, Mizumura S, Soma T, et al : Conversion of brain SPECT images between different collimators and reconstruction processes for analysis using statistical parametric mapping. Nucl Med Commun 25 : 67-74, 2004
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3) Imabayashi E, Yokoyama K, Tsukamoto T, et al : The cingulate island sign within early Alzheimer's diseasespecific hypoperfusion volumes of interest is useful for differentiating Alzheimer's disease from dementia with Lewy bodies. EJNMMI Res 6 : 67, 2016
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4) Imabayashi E, Soma T, Sone D, et al : Validation of the cingulate island sign with optimized ratios for discriminating dementia with Lewy bodies from Alzheimer's disease using brain perfusion SPECT. Ann Nucl Med 31 : 536-43, 2017
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2) Mizumura S, Kumita S : Stereotactic statistical imaging analysis of the brain using the easy Z-score imaging system for sharing a normal database. Radiat Med 24 : 545-52, 2006
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3) 根本清貴, 田村昌士, 新井哲明, 他 : 健常後期高齢者のTc-99m ECD脳血流SPECT データベースの開発. Pharma Medical 32 : 62-3, 2014
 
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