麻酔科プラクティス　2　周術期の輸液・輸血療法　All in One

出版社： 文光堂
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発行日： 2020-07-03
分野： 臨床医学：外科  >  麻酔科学/ペイン
ISBN： 9784830628481
電子書籍版： 2020-07-03 （第1版第1刷）
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商品紹介

〈麻酔プラクティス〉シリーズ第2巻は，「周術期の輸液・輸血療法」を徹底解説．現在，周術期の循環動態の管理には様々なモニターが開発され，患者様の安全性は格段に向上し，輸液・輸血療法の考え方も変化してきている．また，特に輸血療法に関しては、最近多くのガイドラインが作成・改訂され，輸血療法の標準化が進んでいる．さらに，大量出血時の対応についても，ただ輸血するだけではなく，凝固機能のモニターを行いながら，適切な対応を行うことが求められている．このような大きな変革に対応できるような構成となっている．本書は周術期管理を念頭に置いた麻酔科医向けの内容を中心としつつ，輸液・輸血療法のエキスパートによる最新の輸血の知識も網羅．今後の麻酔科臨床の向上に必ず役立つ情報となる．

目次

  • I　総　論
    　１　体液の生理
    　　［K&P］“サードスペース” は，ない？
    　２　栄養
    　　1）経静脈栄養
    　　2）経腸栄養
    　３ 経口補水
    　　［T］ERASプロトコル
    　４　血液浄化と体液
    　５　血液凝固の基礎
    　　［T］水とグリコカリックス

    II　輸液製剤の概要と適応
    　１　目標指向型輸液療法
    　２　細胞外液系輸液剤
    　　1）総論
    　　2）乳酸リンゲル液
    　　3）酢酸リンゲル液
    　　4）生理食塩液
    　　5）フィジオ140 輸液（1％ブドウ糖加酢酸リンゲル液）
    　　6）糖を含んだ細胞外液系輸液剤
    　　7）重炭酸リンゲル液
    　　［B］輸液製剤中の乳酸・酢酸の役割
    　　［B］アニオンギャップ
    　３　維持輸液剤
    　　1）総論
    　　2）5％ブドウ糖液
    　　3）1号液（開始液）
    　　4）2号液（細胞内修復液/脱水補給液）
    　　5）3号液（維持液-1
    　　6）4号液（維持液-2/術後回復液）
    　４　膠質液（ボルベン）
    　５　脂肪乳剤
    　６　アミノ酸製剤
    　　［B］アミノ酸輸液と体温

    III　輸　血
    　１　輸血製剤
    　２　血漿製剤
    　　1）免疫グロブリン
    　　2）アルブミン製剤
    　　3）アンチトロンビン製剤
    　　4）凝固因子製剤
    　３　不規則抗体
    　　［OPA］交差適合試験が間に合わない時の対応

    IV 血液供給体制
    　１　血液供給の現状
    　２　災害時の血液供給体制
    　　［T］熊本地震時の血液供給体制
    　３　ヘモビジランス

    V　輸血ガイドライン
    　１　新しい赤血球製剤の使用ガイドライン
    　　［T］術前貧血補正と制限輸血（Bloodless Medicine）
    　２　大量出血症例に対する血液製剤の適正な使用のガイドライン
    　３　小児輸血のガイドライン
    　４　新しい新鮮凍結血漿使用ガイドラインと大量輸血における使い方
    　５　有害事象の予防と治療のガイドライン
    　６　アルブミン製剤の使用ガイドライン

    VI　輸血医療における止血戦略
    　１　自己血由来フィブリン糊と止血戦略
    　２　抗線溶療法と止血戦略─特にモニタリング方法と対処法─
    　　［B］クリオプレシピテート
    　　［B］濃縮フィブリノゲン製剤

    VII　周術期の輸血療法
    　１　Patient Blood Management（PBM）
    　２　麻酔科医から見た周術期の輸血療法
    　　［OPA］高カリウム血症時の輸血

    VIII　輸血関連合併症・感染症
    　１　Transfusion-Related Acute Lung Injury（TRALI）
    　２　Transfusion Associated Circulatory Overload（TACO）
    　３　血液製剤によるウイルス感染とその対策
    　　［T］E型肝炎
    　４　輸血と細菌感染症―特に血小板製剤による感染―
    　　［K&P］予期せぬ抗体とその対応
    　　［B］ハプトグロビンの適応と作用機序

    IX　自己血輸血
    　１　自己血輸血の実施指針
    　２　整形外科
    　３　婦人科
    　４　心臓血管外科

    X　各種手術の輸液・輸血戦略
    　１　術中大量出血時の循環動態の管理─特に輸血との関係─
    　２　産科領域の大量出血時の対応─特に止血戦略─
    　３　成人心臓外科手術
    　４　小児心臓外科手術
    　５　脳神経外科手術
    　６　肝移植・腎移植
    　７　小児手術
    　８　新生児手術
    　９　外傷手術
    　　［OPA］熱傷時の輸液・輸血管理2

    ［T］＝Topics
    ［B］＝Basic
    ［K&P］＝Knack & Pitfalls
    ［OPA］＝One Point Advice

この書籍の参考文献

参考文献のリンクは、リンク先の都合等により正しく表示されない場合がありますので、あらかじめご了承下さい。

本参考文献は電子書籍掲載内容を元にしております。

I 総論

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II 輸液製剤の概要と適応

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1) 仲村将高ほか : 輸液療法の基礎. 日医師会誌 132 : 19-22, 2004
 
2) 平井亮 : 輸液管理の基礎知識～「どこに, 何が, どれだけ」を考えながらモニタリングしよう～. 重症患者ケア 6 : 635-643, 2017
 
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1) 高折益彦 : 電解質製剤の分類, 名称. 体液代謝管理 34 : 23-29, 2018
 
2) 平井亮 : 輸液管理の基礎知識～「どこに, 何が, どれだけ」を考えながらモニタリングしよう～. 重症患者ケア 6 : 635-643, 2017
 
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1) Fettiplace MR, et al : The mechanisms underlying lipid resuscitation therapy. Reg Anesth Pain Med 43 : 138-149, 2018
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2) 日本麻酔科学会 : 局所麻酔薬中毒への対応プラクティカルガイド. https://anesth.or.jp/files/pdf/practical_localanesthesia.pdf
 
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5) Fettiplace MR, et al : Resuscitation with lipid emulsion : dose-dependent recovery from cardiac pharmacotoxicity requires a cardiotonic effect. Anesthesiology 120 : 915-925, 2014
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8) Fettiplace MR, et al : Insulin signaling in bupivacaine-induced cardiac toxicity : Sensitization during recovery and potentiation by lipid emulsion. Anesthesiology 124 : 428-442, 2016
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2) 外岡亨ほか : 非蛋白熱量/窒素 (NPC/N比) の設定とアミノ酸輸液製剤. 臨栄 126 : 838-843, 2015
 
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6) 溝部俊樹 : 輸液管理におけるserendipity. アミノ酸輸液とフルクトース輸液の新しい可能性. 日臨麻会誌 27 : 426-435, 2007
 
7) Umenai T, et al : Perioperative amino acid infusion improves recovery and shor tens the duration of hospitalization after off-pump coronary artery bypass grafting. Anesth Analg 103 : 1386-1393, 2006
 

III 輸血

P.103 掲載の参考文献
1) 金子祐次ほか : 複数回洗浄した洗浄赤血球製剤の品質. 日輸血細胞治療会誌 63 : 757-762, 2017
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2) 内藤祐ほか : 新鮮凍結血漿の融解後の使用期限. 日輸血細胞治療会誌 60 : 577-584, 2014
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3) 森純平ほか : 成分採血由来新鮮凍結血漿の融解後の品質. 日輸血細胞治療会誌 61 : 550-555, 2015
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7) 平山順一ほか : 自動血球洗浄装置 (ACP215) で調製した洗浄血小板の品質. 日輸血細胞治療会誌 62 : 705-710, 2016
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1) 正岡徹ほか : 重症感染症に対する抗菌薬との併用療法における静注用ヒト免疫グロブリンの効果. 日化療会誌 48 : 199-217, 2000
 
2) 西田修ほか : 日本版敗血症診療ガイドライン2016作成委員会 : 日本版敗血症診療ガイドライン 2016, 91-97, 2017
 
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4) Stiehm ER : Adverse effects of human immunoglobulin therapy. Transfuse Med Rev 27 : 171-178, 2013
 
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1) Boldt J : Use of albumin : an update. Brit Anaesthesia 104 : 276-284, 2010
 
2) 本田義輝ほか : 人血清アルブミン製剤の国内製品と輸入製品に関する品質比較. 新薬と臨床 59 : 1834-1844, 2010
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3) 安村敏ほか : 科学的根拠に基づいたアルブミン製剤の使用ガイドライン (第2版). 日輸血細胞治療会誌 64 : 700-717, 2018
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2) 山本晃士 : 播種性血管内凝固症. とことんわかる血栓症, 中外医学社, 東京, 52-55, 2018
 
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3) Tanaka KA, et al : Role of prothrombin complex concentrate in perioperative coagulation therapy. J Intensive Care 2 : 60, 2014
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4) Cappabianca G, et al : Safety and efficacy of prothrombin complex concentrate as first-line treatment in bleeding after cardiac surgery. Crit Care 20 : 5, 2016
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5) Zeeshan M, et al : Four-factor prothrombin complex concentrate is associated with improved sur vival in trauma-related hemorrhage : A nationwide propensity-matched analysis. J Trauma Acute Care Surg 87 : 274-281, 2019
 
6) Ahonen J : The role of recombinant activated factor VII in obstetric hemorrhage. Curr Opin Anaesthesiol 25 : 309-314, 2012
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7) Zindovic I, et al : Recombinant factor VIIa use in acute type A aortic dissection repair : A multicenter propensity-score-matched report from the Nordic Consortium for Acute Type A Aortic Dissection. J Thorac Cardiovasc Surg 154 : 1852-1859, 2017
 
P.121 掲載の参考文献
1) 藤原晴美ほか : 輸血後の赤血球不規則抗体発現に関する前方向性研究-パイロット試験の結果-. 日輸血細胞治療会誌 65 : 810-816, 2019
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2) 藤井フサ子ほか : 九州大学医学部附属病院における不規則抗体陽性率の実際-10年間の調査-. 日輸血会誌 43 : 364-368, 1997
 
3) 石丸健ほか : 不規則抗体スクリーニング検査の種類・手順・注意点. Medical Technology 39 : 1395-1401, 2011
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4) 厚生労働省医薬食品局血液対策課 : 『輸血療法の実施に関する指針. 平成17年9月 (平成26年11月一部改正)
 
5) 厚生労働省医薬・生活衛生局血液対策課 : 『血液製剤の使用指針 (改定版) 』平成31年3月
 
6) 日本輸血・細胞治療学会 : 赤血球型検査 (赤血球系検査) ガイドライン (改訂2版). 日輸血細胞治療会誌 62 : 651-663, 2016
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7) 国分寺晃 : 不規則抗体の臨床的意義. スタンダード輸血検査テキスト (第3版), 認定輸血検査技師制度協議会カリキュラム委員会編集, 医歯薬出版, 90, 2020
 
8) Janatpour KA, et al : Clinical outcomes of ABO-incompatible RBC transfusions. Am J Clin Pathol 129 : 276-281, 2008
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9) 石田萠子 : パネルディスカッション. 話題提供 : 溶血性輸血反応に関連して. 日輸血細胞治療会誌 37 : 682-686, 1991
 
10) 澤部孝昭ほか : 遅発性溶血性輸血副作用の検討-過去10年間の検討. 日輸血細胞治療会誌 39 : 974-978, 1993
 
11) 山口富子ほか : 複数抗体 (抗C, 抗e, 抗Jka, 抗P1抗体) により短期間に2回連続して発症した遅発性溶血性輸血副作用. 日輸血細胞治療会誌 43 : 896-900, 1997
 
12) 佐久間志津枝ほか : 抗Dia, 抗Jkb, 抗E抗体により3回の遅発性溶血性輸血副作用を呈した血友病Bと. 病院内輸血システムの改善. 医学検査 49 : 1198-1201, 2000
 
13) 北沢淳一ほか : 携帯「不規則抗体カード」が輸血副作用防止に有効だった1例. 日輸血細胞治療会誌 54 : 503-506, 2008
 
14) 日本麻酔科学会, 日本輸血・細胞治療学会 : 危機的出血への対応ガイドライン, 2007年11月改訂
 
15) 日本産科婦人科学会, 日本産婦人科医会, 日本周産期・新生児医学会, 日本麻酔科学会, 日本輸血・細胞治療学会 : 産科危機的出血への対応指針, 2017
 
P.123 掲載の参考文献
1) 厚生労働省医薬食品局血液対策課 : 輸血療法の実施に関する指針. 2005年9月 (2014年11月一部改正)
 
2) 厚生労働省医薬・生活衛生局血液対策課 : 血液製剤の使用指針 (改定版), 2019年3月
 
3) 日本輸血・細胞治療学会 : 赤血球型検査 (赤血球系検査) ガイドライン (改訂2版). 日輸血細胞治療会誌 62 : 651-663, 2016
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4) 日本輸血・細胞治療学会 : 輸血検査技術 輸血のための検査マニュアル Ver.1.3.1
 
5) 日本麻酔科学会, 日本輸血・細胞治療学会 : 危機的出血への対応ガイドライン, 2007年11月改訂
 
6) 日本産科婦人科学会, 日本産婦人科医会, 日本周産期・新生児医学会, 日本麻酔科学会, 日本輸血・細胞治療学会 : 産科危機的出血への対応指針, 2017
 

IV 血液供給体制

P.131 掲載の参考文献
1) Kano C : Estimate of future blood demand in Japan and the number of blood donations required. ISBT Science Series 13 : 405-411, 2018
 
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1) 田所憲治 : 血液事業の広域化～現状と課題. 医学のあゆみ 247 : 231-235, 2013
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2) 静岡県健康福祉部 : 静岡県医療救護計画, 2019
 
3) 熊本県健康福祉部 : 熊本県災害時医療救護マニュアル, 2018
 
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1) 続隆文ほか : 平成28年熊本地震における輸血用血液製剤の供給状況. 日血栓止血会誌 28 : 708-713, 2017
 
P.143 掲載の参考文献
1) 藤井康彦ほか : 診療科別輸血製剤副作用発生率の調査. 日輸血細胞治療会誌 62 : 451-458, 2016
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2) Odaka C, et al : Online reporting system for transfusion-related adverse events to enhance recipient haemovigilance in Japan : a pilot study. Transfusion and Apheresis Science 48 : 95-102, 2013
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3) 岩尾憲明ほか : 輸血副作用サーベイランスにおけるunderreporting. 日輸細治会誌 61 : 561-566, 2015
 
4) 松岡佐保子ほか : 輸血医療におけるトレーサビリティ確保-医療施設で収集すべきチェック項目の設定-. 日輸血細胞治療会誌, 印刷中
 
5) Chapman CE, et al : Ten years of hemovigilance reports of transfusion-related acute lung injury in the United Kingdom and the impact of preferential use of male donor plasma. Transfusion 49 : 440-452, 2009
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6) 岡崎仁 : TRALI/TACOの病態と診断. 日輸血細胞治療会誌 59 : 21-29, 2013
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V 輸血ガイドライン

P.151 掲載の参考文献
1) 米村雄士ほか : 科学的根拠に基づいた赤血球製剤の使用ガイドライン. 日輸血細胞治療会誌 62 : 641-650, 2016
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2) 福井次矢ほか : Minds診療ガイドライン作成の手引き 2014, 医学書院, 東京, 2014
 
3) 「難治性貧血の診療ガイド」編集委員会 : 難治性貧血の診療ガイド : 特発性造血障害の病態・診断・治療の最新動向, 南江堂, 東京, 2011
 
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6) 研究代表者 : 小澤敬也, 厚生労働科学研究費補助金難治性疾患克服研究事業特発性造血障害に関する調査研究 (平成20年度) 輸血後鉄過剰症の診療ガイド, 2008
 
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VI 輸血医療における止血戦略

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VII 周術期の輸血療法

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VIII 輸血関連合併症・感染症

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IX 自己血輸血

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X 各種手術の輸液・輸血戦略

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