心原性脳塞栓症と経口抗凝固薬

出版社： フジメディカル出版
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発行日： 2013-04-01
分野： 臨床医学：内科  >  血管
ISBN： 9784862700445
電子書籍版： 2013-04-01 （初版第2刷）
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新たな経口抗凝固薬，直接トロンビン阻害薬と活性化凝固第?因子阻害薬を，いかにして使いこなすか？　モニタリングは？　出血への対応は？　どう使い分けるのか？　臨床試験からは読み取れない課題への解決の糸口を示す，脳卒中医家必携の1冊！　いま知りたい疑問への答えを全4章18項目に凝縮されています。

目次

  • 心原性脳塞栓症と経口抗凝固薬

    ―目次―

    1．病態と治療の基礎知識
    　心房細動とその塞栓症リスク
    　心原性脳塞栓症の臨床像
    　凝固・線溶系の生理と病理
    　抗凝固療法・抗血小板療法とは何か

    2．経口抗凝固薬の特徴と臨床試験成績
    　ワルファリンはどんな薬か
    　ダビガトランはどんな薬か
    　リバーロキサバンはどんな薬か
    　アピキサバンはどんな薬か
    　エドキサバンはどんな薬か

    3．新規抗凝固薬の臨床応用
    　市販後の使用状況と市販後調査
    　新規抗凝固薬のモニタリング
    　新規抗凝固薬による出血事故と対応策
    　禁忌・副作用・相互作用

    4．脳卒中診療現場での新規抗凝固療法
    　脳梗塞急性期にどう使い始めるか
    　脳神経血管内治療患者にどのように用いるか
    　脳神経外科手術患者，周術期患者にどう管理するか
    　服用患者に急性期再開通治療は可能か
    　慢性期の再発予防にどのように用いるか

この書籍の参考文献

参考文献のリンクは、リンク先の都合等により正しく表示されない場合がありますので、あらかじめご了承下さい。

本参考文献は電子書籍掲載内容を元にしております。

1. 病態と治療の基礎知識

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2. 経口抗凝固薬の特徴と臨床試験成績

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P.63 掲載の参考文献
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2) Hori M et al:Rivaroxaban vs. warfarin in Japanese patients with atrial fibrillation-the J-ROCKET AF study-. Circ J 76:2104-2111, 2012
 
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P.71 掲載の参考文献
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3. 新規抗凝固薬の臨床応用

P.87 掲載の参考文献
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2) Patel MR et al; ROCKET AF Investigators:Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med 365:883-891, 2011
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P.112 掲載の参考文献
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2) Patel MR et al:Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med 365:883-891, 2011
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3) Hori M et al:Rivaroxaban vs. warfarin in Japanese patients with atrial fibrillation-the J-ROCKET AF study-. Circ J 76:2104-2111, 2012
 
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5) Granger CB et al:Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med 365:981-992, 2011
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6) Fox KA et al:Prevention of stroke and systemic embolism with rivaroxaban compared with warfarin in patients with non-valvular atrial fibrillation and moderate renal impairment. Eur Heart J 32:2387-2394, 2011
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4. 脳卒中診療現場での新規抗凝固療法

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10) Granger CB et al:Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med 365(11):981-992, 2011
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11) Ruff CT et al:Evaluation of the novel factor Xa inhibitor edoxaban compared with warfarin in patients with atrial fibrillation:design and rationale for the Effective aNticoaGulation with factor xA next GEneration in Atrial Fibrillation-Thrombolysis In Myocardial Infarction study 48 (ENGAGE AF-TIMI 48). Am Heart J 160(4):635-641, 2010
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